[1]万玉峰.超声引导下射频消融术对甲状腺微小乳头状癌的疗效及术后应激的影响[J].医学信息,2023,36(08):112-115.[doi:10.3969/j.issn.1006-1959.2023.08.023]
　WAN Yu-feng.Effect of Ultrasound-guided Radiofrequency Ablation on Papillary Thyroid Microcarcinoma and Postoperative Stress[J].Journal of Medical Information,2023,36(08):112-115.[doi:10.3969/j.issn.1006-1959.2023.08.023]
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超声引导下射频消融术对甲状腺微小乳头状癌的疗效及术后应激的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年08期
页码:
112-115
栏目:
论著
出版日期:
2023-04-15

文章信息/Info

Title:
Effect of Ultrasound-guided Radiofrequency Ablation on Papillary Thyroid Microcarcinoma and Postoperative Stress
文章编号:
1006-1959（2023）08-0112-04
作者:
万玉峰
（佳木斯市中心医院普外一科，黑龙江 佳木斯 154003）
Author(s):
WAN Yu-feng
(The First Department of General Surgery,Jiamusi Central Hospital,Jiamusi 154003,Heilongjiang,China)
关键词:
超声引导; 射频消融术; 甲状腺微小乳头状癌; 应激反应
Keywords:
Ultrasound-guided; Radiofrequency ablation; Papillary thyroid carcinoma; Stress response
分类号:
R736.1
DOI:
10.3969/j.issn.1006-1959.2023.08.023
文献标志码:
A
摘要:
目的 研究超声引导下射频消融术对甲状腺微小乳头状癌的疗效及患者术后应激的影响。方法 选择2019年5月-2021年6月我院收治的84例甲状腺微小乳头状癌患者为研究对象，采用随机数字表法分为对照组（42例）和观察组（42例）。对照组采用常规手术切除治疗，观察组采用超声引导下射频消融术治疗，比较两组手术指标、甲状腺激素水平、肿瘤体积、术后应激反应指标、并发症发生率及复发率。结果 观察组手术时间、术中出血量、疼痛消失时间均小于对照组（P＜0.05）；观察组术后三碘甲状腺原氨酸（FT3）、游离甲状腺激素（FT4）、高敏感促甲状腺激素（TSH）水平与术前比较，差异无统计学意义（P＞0.05）；对照组术后FT3、FT4低于术前，TSH高于术前（P＜0.05）；观察组FT3、FT4均高于对照组，TSH低于对照组（P＜0.05）；两组术后肿瘤体积比较，差异无统计学意义（P＞0.05）；两组肿瘤坏死因子-α（TNF-α）、白细胞介素-6（IL-6）均高于术前，但观察组低于对照组（P＜0.05）；观察组并发症发生率低于对照组（P＜0.05）；随访3个月，两组复发率比较，差异无统计学意义（P＞0.05）。结论 超声引导下射频消融术和常规手术切除均可缩小甲状腺微小乳头状癌病灶体积，相对而言超声引导下射频消融术可缩短手术时间，减轻创伤，缩短疼痛时间，减小对患者甲状腺功能、术后应激反应的影响，降低并发症发生率，且不会增加复发率，具有良好的安全性。
Abstract:
Objective To study the effect of ultrasound-guided radiofrequency ablation on papillary thyroid microcarcinoma and its effect on postoperative stress.Methods A total of 84 patients with papillary thyroid microcarcinoma admitted to our hospital from May 2019 to June 2021 were selected as the research objects. They were divided into control group (42 cases) and observation group (42 cases) by random number table method. The control group was treated with conventional surgical resection, and the observation group was treated with ultrasound-guided radiofrequency ablation. The surgical indexes, thyroid hormone levels, tumor volume, postoperative stress response indexes, complication rate and recurrence rate were compared between the two groups.Methods The operation time, intraoperative blood loss and pain disappearance time of the observation group were less than those of the control group (P<0.05). There was no significant difference in the levels of triiodothyronine (FT3), free thyroid hormone (FT4) and high sensitive thyroid stimulating hormone (TSH) between the observation group and the preoperative group (P>0.05). FT3 and FT4 were lower than those before operation, and TSH was higher than that before operation in the control group (P<0.05). FT3 and FT4 in the observation group were higher than those in the control group, and TSH was lower than that in the control group (P<0.05). There was no significant difference in postoperative tumor volume between the two groups (P>0.05). The levels of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in the two groups were higher than those before operation, but those in the observation group were lower than the control group (P<0.05). The incidence of complications in the observation group was lower than that in the control group (P<0.05). After 3 months of follow-up, there was no significant difference in recurrence rate between the two groups (P>0.05).Conclusion Ultrasound-guided radiofrequency ablation and conventional surgical resection can reduce the volume of thyroid micropapillary carcinoma lesions. Relatively, ultrasound-guided radiofrequency ablation can shorten the operation time, reduce trauma, shorten the pain time, reduce the impact on thyroid function and postoperative stress response, reduce the incidence of complications, and will not increase the recurrence rate, with good safety.

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更新日期/Last Update: 1900-01-01