[1]董洪克,卢雨蓓.基于CiteSpace国内肝癌细胞自噬相关文献的可视化分析[J].医学信息,2024,37(03):26-32.[doi:10.3969/j.issn.1006-1959.2024.03.005]
　DONG Hong-ke,LU Yu-bei.Visual Analysis of Domestic Literatures Related to Autophagy of Hepatoma Cells Based on CiteSpace[J].Journal of Medical Information,2024,37(03):26-32.[doi:10.3969/j.issn.1006-1959.2024.03.005]
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基于CiteSpace国内肝癌细胞自噬相关文献的可视化分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
37卷
期数:
2024年03期
页码:
26-32
栏目:
医学数据科学
出版日期:
2024-02-01

文章信息/Info

Title:
Visual Analysis of Domestic Literatures Related to Autophagy of Hepatoma Cells Based on CiteSpace
文章编号:
1006-1959（2024）03-0026-07
作者:
董洪克; 卢雨蓓
（1.甘肃中医药大学中医临床学院，甘肃 兰州 730000；2.甘肃省中医院肝病科，甘肃 兰州 730050）
Author(s):
DONG Hong-ke; LU Yu-bei
(1.Clinical Medicine of Traditional Chinese Medicine,Gansu University of Traditional Chinese Medicine,Lanzhou 730000,Gansu,China;2.Department of Hepatology,Gansu Hospital of Traditional Chinese Medicine,Lanzhou 730050,Gansu,China)
关键词:
肝癌; 细胞自噬; CiteSpace; 可视化分析; 文献计量学
Keywords:
Hepatocarcinoma; Cell autophagy; CiteSpace; Visual analysis; Bibliometrics
分类号:
R575；G353.1
DOI:
10.3969/j.issn.1006-1959.2024.03.005
文献标志码:
A
摘要:
目的 筛选、整理近20年国内肝癌细胞自噬相关文献并进行知识图谱可视化分析，揭示该领域的研究热点、历史演进及未来的发展趋势。方法 检索中国知网、万方、维普数据库中2001年1月-2023年2月肝癌细胞自噬的相关文献，利用CiteSpace 6.1.R6软件对符合纳入标准、排除标准的文献进行文献数量发布趋势、作者合作、机构合作、关键词和时间知识图谱可视化分析。结果 共纳入495篇文献。该领域文献数量发布量整体呈上升趋势，涉及的作者462位，研究机构为287所，作者发文量最高产的是邱伟华、刘凯。存在6个合作较密切的团队，其中以邱伟华团队合作最紧密，发文量最多的机构是上海交通大学医学院附属瑞金医院。近5年的热点关键词主要集中在机制、预后、抗肿瘤、耐药性。关键词形成9个聚类标签，主要概括为肝癌细胞自噬的细胞机制、药物治疗、文献研究。结论 该领域研究热点主要集中于细胞机制和治疗。该领域机构内部合作较多，机构间尚未形成稳定的研究团队，今后需要加强机构间合作，增加学术交流的机会和平台，以进一步指导临床。
Abstract:
Objective To screen and sort out the literature related to autophagy of hepatoma cells in China in the past 20 years and conduct visual analysis of knowledge map, so as to reveal the research hotspots, historical evolution and future development trends in this field.Methods The related literatures on autophagy of hepatoma cells from January 2001 to February 2023 in China National Knowledge Infrastructure (CNKI), Wanfang and VIP database were searched. CiteSpace 6.1.R6 software was used to analyze the trend of literature number, author cooperation, institutional cooperation, keywords and time knowledge map visualization of the literatures that met the inclusion criteria and exclusion criteria.Results A total of 495 articles were included, the number of papers published in this field showed an overall upward trend, involving 462 authors and 287 research institutions. QIU Wei-hua and LIU Kai were the most productive authors, and there were six teams with close cooperation. Among them, QIU Wei-hua works most closely, and the institution with the largest volume of publication was Ruijin Hospital, Shanghai Jiao Tong University School of Medicine. In the past 5 years, the hot keywords mainly focused on mechanism, prognosis, anti-tumor and drug resistance; the key words formed 9 cluster tags, which were mainly summarized as the cellular mechanism of autophagy of hepatoma cells, drug therapy and literature research.Conclusion The research hotspots in this field are mainly focused on cellular mechanism and therapy, and there are many internal cooperation in this field, but a stable research team has not yet been formed among institutions. In the future, it is necessary to strengthen inter-agency cooperation and increase the opportunities and platforms for academic exchanges to further guide clinical practice.

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更新日期/Last Update: 1900-01-01