[1]黄康凯.解毒通腑汤加减治疗对阑尾炎患者术后免疫功能及胃肠功能恢复的影响[J].医学信息,2025,38(12):144-147.[doi:10.3969/j.issn.1006-1959.2025.12.031]
　HUANG Kangkai.Effect of Modified Jiedu Tongfu Decoction on Postoperative Immune Function and Gastrointestinal Function Recovery in Patients with Appendicitis[J].Journal of Medical Information,2025,38(12):144-147.[doi:10.3969/j.issn.1006-1959.2025.12.031]
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解毒通腑汤加减治疗对阑尾炎患者术后免疫功能及胃肠功能恢复的影响()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
38卷
期数:
2025年12期
页码:
144-147
栏目:
论著
出版日期:
2025-06-15

文章信息/Info

Title:
Effect of Modified Jiedu Tongfu Decoction on Postoperative Immune Function and Gastrointestinal Function Recovery in Patients with Appendicitis
文章编号:
1006-1959（2025）12-0144-04
作者:
黄康凯
铅山县中医院外一科，江西 铅山 334500
Author(s):
HUANG Kangkai
The First Department of Surgery, Yanshan County Hospital of Traditional Chinese Medicine, Yanshan 334500, Jiangxi, China
关键词:
阑尾炎; 解毒通腑汤; 胃肠功能恢复; 免疫功能; 术后疼痛
Keywords:
Appendicitis;  Jiedu Tongfu decoction;  Gastrointestinal function recovery;  Immune function;  Postoperative pain
分类号:
R574.61
DOI:
10.3969/j.issn.1006-1959.2025.12.031
文献标志码:
A
摘要:
目的 研究解毒通腑汤加减治疗对阑尾炎患者术后免疫功能及胃肠功能恢复的影响。方法 以2020年1月-2023年12月铅山县中医院行阑尾切除术治疗的63例患者为研究对象，经随机数字表法将患者分为对照组（31例）与观察组（32例）。对照组行常规术后抗感染治疗，观察组在其基础上联合解毒通腑汤加减治疗，比较两组术后胃肠功能恢复时间（肠鸣音恢复时间、肛门排气时间、首次排便时间）、术后疼痛程度[视觉模拟评分（VAS）]、术后免疫功能[白介素（IL）-1β、IL-6]、术后并发症。结果 与对照组比较，观察组术后肠鸣音恢复时间、肛门排气时间、首次排便时间缩短（P＜0.05）；与对照组比较，观察组术后12、24 h的VAS评分降低（P＜0.05）；两组术后 72 h的IL-1β、IL-6指标均低于术后5 h，且与对照组比较，观察组术后 72 h的IL-1β、IL-6指标降低（P＜0.05）；与对照组比较，观察组术后并发症发生率为6.25%，对照组术后并发症发生率为19.35%，组间比较，差异有统计学意义（P＜0.05）。结论 解毒通腑汤加减治疗可加快阑尾炎患者术后胃肠功能恢复，减轻其术后疼痛程度，改善患者免疫功能，降低相关并发症的发生风险。
Abstract:
Objective To study the effect of modified Jiedu Tongfu decoction on postoperative immune function and gastrointestinal function recovery in patients with appendicitis. Methods Using the random number table method, 63 patients who underwent appendectomy in Yanshan County Hospital of Traditional Chinese Medicine from January 2020 to December 2023 were divided into control group (31 patients) and observation group (32 patients). The control group was treated with routine postoperative anti-infection treatment, and the observation group was treated with modified Jiedu Tongfu decoction on the basis of the control group. The postoperative gastrointestinal function recovery time (bowel sound recovery time, anal exhaust time, first defecation time), postoperative pain degree [Visual Analogue Scale (VAS)], postoperative immune function [interleukin (IL)-1β, IL-6], postoperative complications were compared between the two groups. Results Compared with the control group, the recovery time of bowel sounds, anal exhaust time and first defecation time in the observation group were shortened (P<0.05). Compared with the control group, the VAS score of the observation group at 12 and 24 h after operation was decreased (P<0.05). The levels of IL-1β and IL-6 at 72 h after operation in the two groups were lower than those at 5 h after operation, and the levels of IL-1β and IL-6 at 72 h after operation in the observation group were lower than those in the control group (P<0.05). Compared with the control group, the incidence of postoperative complications in the observation group was 6.25%, and the incidence of postoperative complications in the control group was 19.35%, the difference between the two groups was statistically significant (P<0.05). Conclusion Modified Jiedu Tongfu decoction can accelerate the recovery of gastrointestinal function in patients with appendicitis, reduce the degree of postoperative pain, improve the immune function of patients, and reduce the risk of related complications.

参考文献/References:

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更新日期/Last Update: 1900-01-01