[1]廖镜清.腹腔镜胆囊切除术对急性胆源性胰腺炎患者的治疗效果及对血清淀粉酶水平的影响[J].医学信息,2025,38(18):83-86,90.[doi:10.3969/j.issn.1006-1959.2025.18.018]
　LIAO Jingqing.Therapeutic Effect of Laparoscopic Cholecystectomy on Patients with Acute Biliary Pancreatitisand its Effect on Serum Amylase Level[J].Journal of Medical Information,2025,38(18):83-86,90.[doi:10.3969/j.issn.1006-1959.2025.18.018]
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腹腔镜胆囊切除术对急性胆源性胰腺炎患者的治疗效果及对血清淀粉酶水平的影响()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
38卷
期数:
2025年18期
页码:
83-86,90
栏目:
论著
出版日期:
2025-09-15

文章信息/Info

Title:
Therapeutic Effect of Laparoscopic Cholecystectomy on Patients with Acute Biliary Pancreatitisand its Effect on Serum Amylase Level
文章编号:
1006-1959（2025）18-0083-05
作者:
廖镜清
安远县人民医院胃肠肝胆外科，江西 安远 342100
Author(s):
LIAO Jingqing
Department of Gastroenterology and Hepatobiliary Surgery, Anyuan County People’s Hospital, Anyuan 342100, Jiangxi, China
关键词:
腹腔镜胆囊切除术; 急性胆源性胰腺炎; 血清淀粉酶; 炎性因子
Keywords:
Laparoscopic cholecystectomy;  Acute biliary pancreatitis;  Serum amylase;  Inflammatory factors
分类号:
R657.5+1
DOI:
10.3969/j.issn.1006-1959.2025.18.018
文献标志码:
A
摘要:
目的 观察腹腔镜胆囊切除术治疗急性胆源性胰腺炎的临床效果，分析该方案对患者血清淀粉酶水平的影响。方法 将安远县人民医院2022年1月-2023年12月收治的100例急性胆源性胰腺炎患者按照随机数字表法分为对照组50例和研究组50例。对照组患者采用开放性胆囊切除术进行治疗，研究组患者采用腹腔镜胆囊切除术治疗。比较两组患者的治疗效果、临床手术指标（手术时间、术中出血量、下床活动时间、肠胃功能恢复时间、住院时间）、血清淀粉酶水平、血清炎性因子[C-反应蛋白（CRP）、白介素-6（IL-6）、肿瘤坏死因子-α（TNF-α）]及术后并发症情况。结果 研究组治疗总有效率高于对照组（P＜0.05）。研究组手术时间、术中出血量、下床活动时间、肠胃功能恢复时间、住院时间均低于对照组（P＜0.05）。治疗后，研究组血清淀粉酶水平低于对照组（P＜0.05）。研究组血清炎性因子水平均低于对照组（P＜0.05）。研究组术后并发症发生率低于对照组（P＜0.05）。结论 采用腹腔镜胆囊切除术治疗急性胆源性胰腺炎患者的效果良好，能够优化临床指标水平，改善患者血清淀粉酶以及炎性因子水平，且安全性较高，值得临床应用。
Abstract:
Objective To investigate the therapeutic effect of laparoscopic cholecystectomy on patients with acute biliary pancreatitis and its effect on serum amylase level. Methods A total of 100 patients with acute biliary pancreatitis admitted to Anyuan County People’s Hospital from January 2022 to December 2023 were selected as the research objects. According to the random number table method, they were divided into control group and study group, with 50 patients in each group. The control group was treated with open cholecystectomy, and the study group was treated with laparoscopic cholecystectomy. The therapeutic effect, clinical surgical indexes (operation time, intraoperative blood loss, ambulation time, gastrointestinal function recovery time, hospitalization time), serum amylase level, serum inflammatory factors [C reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α)], and incidence of postoperative complications were compared between the two groups. Results The total effective rate of treatment in the study group was higher than that in the control group (P<0.05). The operation time, intraoperative blood loss, ambulation time, gastrointestinal function recovery time and hospitalization time of the study group were lower than those of the control group (P<0.05). After treatment, the serum amylase level in the study group was lower than that in the control group (P<0.05). The levels of serum inflammatory factors in the study group were lower than those in the control group (P<0.05). The incidence of postoperative complications in the study group was lower than that in the control group (P<0.05). Conclusion Laparoscopic cholecystectomy is effective in the treatment of patients with acute biliary pancreatitis, which can optimize the level of clinical indicators, improve the level of serum amylase and inflammatory factors, and has high safety. It is worthy of clinical application.

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更新日期/Last Update: 1900-01-01