[1]贾海英,黄睿,王玲玲,等.多发性骨髓瘤患者淋巴细胞亚群变化对免疫功能的影响研究[J].医学信息,2018,31(01):147-148.[doi:10.3969/j.issn.1006-1959.2018.01.057]
 JIA Hai-ying,HUANG Rui,WANG Ling-ling,et al.The Effect of Lymphocyte Subgroup Changes on Immune Function in Patients with Multiple Myeloma[J].Journal of Medical Information,2018,31(01):147-148.[doi:10.3969/j.issn.1006-1959.2018.01.057]
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多发性骨髓瘤患者淋巴细胞亚群变化对免疫功能的影响研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年01期
页码:
147-148
栏目:
诊疗技术
出版日期:
2018-01-01

文章信息/Info

Title:
The Effect of Lymphocyte Subgroup Changes on Immune Function in Patients with Multiple Myeloma
文章编号:
1006-1959(2018)01-0147-02
作者:
贾海英1黄睿1王玲玲1黄国虹1杨丽玮1余亮2王昌敏1
新疆维吾尔自治区人民医院临床检验中心1,儿科2,新疆乌鲁木齐830001
Author(s):
JIA Hai-ying1HUANG Rui1WANG Ling-ling1HUANG Guo-hong1YANG Li-wei1YU Liang2WANG Chang-min1
Clinical Laboratory 1, Pediatrics 2, People's Hospital of Xinjiang Uygur Autonomous Region,Urumqi830001,Xinjiang,China
关键词:
多发性骨髓瘤淋巴细胞亚群流式细胞术
Keywords:
Key words:Multiple myelomaLymphocyte subgroupFlow cytometry
分类号:
R733.3
DOI:
10.3969/j.issn.1006-1959.2018.01.057
文献标志码:
A
摘要:
目的分析多发性骨髓瘤(MM)患者外周血T 淋巴细胞尧B 淋巴细胞和自然杀伤(NK)细胞的变化遥方法收集69 例 MM 患者及52 例健康体检人员的抗凝血,用流式细胞仪检测外周血淋巴细胞总数(Lym)尧CD3+ T 淋巴细胞尧CD19+ B 淋巴细 胞及CD16+56+NK细胞数量遥结果与对照组比较,MM 组Lym尧CD3+尧CD4+尧CD8+尧CD4+/CD8+尧CD19+等6个项目差异均有 统计学意义(约0.05),CD16+56+差异无统计学意义(跃0.05)遥结论MM患者在疾病进程中与T淋巴细胞亚群及B淋巴细胞尧 Lym 密切相关,对评价MM 患者的免疫状况尧疾病进展和疗效等方面具有重要作用遥
Abstract:
Abstract:Objective To analyze the multiple myeloma (MM)in peripheral blood of patients with T lymphocytes,B lymphocytes and natural killer (NK) cell changes.Methods Anticoagulated blood were collected from 69 MM patients and 52 cases of healthy people, with the total number of flow cytometry in peripheral blood lymphocytes(Lym),CD3+T lymphocytes,CD19+B lymphocytes and CD16+56+ NK cells.Results Compared with the control group,MM group,Lym,CD3+ ,CD4+ ,CD8+ ,CD4+/CD8+ ,CD19+and other 6 projects,the differences were statistically significant ( <0.05),there was no significant difference between CD16+56+( >0.05).Conclusion The MM patients in disease progression and T lymphocyte subsets and B lymphocytes, closely related to Lym to evaluate the immune status of patients with MM,and has an important role in disease progression and therapeutic effect

参考文献/References:

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更新日期/Last Update: 2018-01-22