[1]胡雪瑞,戢艳琼.1例PCI术后盐酸替罗非班诱导的极重度血小板减少的护理[J].医学信息,2018,31(14):183-185.[doi:10.3969/j.issn.1006-1959.2018.14.058]
　HU Xue-rui,JI Yan-qiong.Nursing Care of a Case of Extremely Severe Thrombocytopenia Induced by Tirofiban Hydrochloride after PCI[J].Journal of Medical Information,2018,31(14):183-185.[doi:10.3969/j.issn.1006-1959.2018.14.058]
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1例PCI术后盐酸替罗非班诱导的极重度血小板减少的护理()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年14期
页码:
183-185
栏目:
护理研究
出版日期:
2018-07-15

文章信息/Info

Title:
Nursing Care of a Case of Extremely Severe Thrombocytopenia Induced by Tirofiban Hydrochloride after PCI
文章编号:
1006-1959（2018）14-0183-03
作者:
胡雪瑞; 戢艳琼
十堰市太和医院湖北医药学院附属医院心血管内科，湖北 十堰 442000
Author(s):
HU Xue-rui; JI Yan-qiong
Affiliated Hospital of Hubei Institute of Medicine,Shiyan Taihe Hospital,Shiyan 442000,Hubei,China
关键词:
盐酸替罗非班; 血小板糖蛋白GPⅡb/Ⅲa受体拮抗剂; 血小板减少症
Keywords:
Key words：Tirofiban hydrochloride; Platelet glycoprotein GPⅡb/Ⅲa receptor antagonist; Thrombocytopenia
分类号:
R473.5
DOI:
10.3969/j.issn.1006-1959.2018.14.058
文献标志码:
A
摘要:
目的 探讨冠状动脉介入术后患者盐酸替罗非班诱发的极重度血小板减少症的临床特点及护理情况，为替罗非班诱导的血小板减少症患者护理提供临床参考。方法 2017年11月我院收治1例急性冠状动脉综合征患者，PCI术后应用盐酸替罗非班致极重度GIT的临床资料及护理情况进行报告。结果 患者PCI术前血小板计数正常，术后应用盐酸替罗非班6 h后出现全身多处瘀斑，血小板计数严重下降至0×109/L，立即停用替罗非班、阿司匹林、氯吡咯雷，并输注血小板、冷冻血浆及使用糖皮质激素治疗，做好防出血护理、用药护理、生活护理、心理干预，血小板计数逐渐升高，约84 h恢复正常。结论 PCI患者应用盐酸替罗非班有诱导的GIT发生风险，积极监测患者血小板变化，加强防出血护理及心理干预，能促进病情恢复。
Abstract:
Abstract：Objective To explore the clinical characteristics and nursing of tirofiban hydrochloride induced thrombocytopenia in patients after coronary intervention,and to provide clinical reference for the nursing of tirofiban hydrochloride induced thrombocytopenia.Methods 1 patient with acute coronary syndrome were treated in our hospital in November 2017.The clinical data and nursing care of patients with severe GIT after tirofiban hydrochloride after PCI were reported.Results The platelet count was normal before PCI.After 6 h of administration of tirofiban hydrochloride,there were many ecchymosis in the whole body.The platelet count decreased to 0×109/L.Immediately discontinue tirofiban,aspirin,clopidogrel,and infusion of platelets,frozen plasma and treatment with glucocorticoids,anti-bleeding care,medication care,life care,psychological intervention,platelet count gradually increased,about 84 h returned to normal.Conclusion PCI patients with tirofiban hydrochloride induced risk of GIT,actively monitor patients with platelet changes,strengthen anti-bleeding care and psychological intervention,can promote the recovery of the disease.

参考文献/References:

[1]中华医学会心血管病学分会,中华心血管病杂志编辑委员会.非ST段抬高急性冠脉综合征诊断和治疗指南[J].中华心血管病杂志,2012,40(5):353-367. [2]Aster RH.Immune thrombocytopenia caused by glycoprotein Ⅱb/Ⅲa inhibitors[J].Chest,2005,127(2 Suppl):53-59. [3]Said SM,Hahn J,Scheleyer E,et al.Glcoprotein Ⅱb/Ⅲa induced thrombocytopenia:diagnosis and treatment[J].Clin Res Cardiol,2007,96(2):61-69.

更新日期/Last Update: 2018-07-15