[1]王 蕊,陈金萍.基于指南的急诊依替米星使用合理性分析[J].医学信息,2018,31(21):125-128.[doi:10.3969/j.issn.1006-1959.2018.21.035]
　WANG Rui,CHEN Jin-ping.Analysis on Rational Use of Etimicin from the Emergency Department Based on Guideline[J].Journal of Medical Information,2018,31(21):125-128.[doi:10.3969/j.issn.1006-1959.2018.21.035]
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基于指南的急诊依替米星使用合理性分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年21期
页码:
125-128
栏目:
调查分析
出版日期:
2018-11-01

文章信息/Info

Title:
Analysis on Rational Use of Etimicin from the Emergency Department Based on Guideline
文章编号:
1006-1959（2018）21-0125-04
作者:
王 蕊; 陈金萍
首都医科大学石景山教学医院药剂科，北京 100043
Author(s):
WANG Rui; CHEN Jin-ping
Department of Pharmacy,Shijingshan Teaching Hospital,Beijing 100043,China
关键词:
依替米星; 抗生素使用; 治疗指南
Keywords:
Etimicin; Antibiotic use; Treatment guideline
分类号:
R978
DOI:
10.3969/j.issn.1006-1959.2018.21.035
文献标志码:
B
摘要:
目的 对我院急诊依替米星处方合理性进行分析，为抗菌药物的合理应用提供参考依据。方法 调阅2017年1月1日~12月31日首都医科大学石景山教学医院急诊科依替米星处方共2599张，依据疾病的治疗指南对处方的合理性进行分析。结果 依替米星使用率排名前三位的诊断为腹腔感染（59.87%）、皮肤软组织感染（58.91%）、泌尿系感染（55.91%），将依替米星作为该诊断的经验性用药与指南推荐的一线用药不符。依替米星用于年龄较轻、无基础疾病青壮年的呼吸道感染治疗亦为不合理用药。结论 我院依替米星使用存在一定的不合理现象。抗感染药物的选择应遵循疾病的治疗指南并结合病原学及药物的药代动力学特点，建议不要将依替米星作为经验性治疗的常规推荐。
Abstract:
Objective Analysis on rational use of Etimicin from the emergency department in hospital to provide referential significance of rational administration of antibiotic. Methods A total of 2599 Etimicin prescriptions of emergency department was collected from January 1，2017 to December 31，2017. Analysis the prescriptions reasonableness based on the guidelines of the treatment of disease. Results The top three diagnosis of using Etimicin were abdominal infection（59.87%）、skin and soft tissues infection（58.91%）、urinary tract infection（55.91%）,empirical use of Eitmicin in this diagnosis is inconsistent with the guidelines recommended first-line medication. The use of etimicin for the treatment of respiratory infections in younger, younger age-free diseases is also an irrational use. Conclusion There was certain irrational use of Eitmicin in our emergency department. The choice of antibiotics should depend on guidelines of treatment、pathogen and pharmacokinetics. It is not recommended to use Etimicin as a routine recommendation for empiric therapy.

参考文献/References:

[1]盛瑞媛,徐小薇,李大魁.治疗指南:抗生素分册[M].北京:化学工业出版社,2018:492-502. [2]Mazuski JE,Sawyer RG,Nathens AB,et al.The Surgical Infection Society guidelines on antimicrobial therapy for intra-abdominal infections: An executive summary[J].Surgical Infections,2002,3(3)：161-173 [3]Mazuski JE,Tessier JM,May AK,et al.The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection[J].Surg Infect(Larchmt),2017,18(1):1-76. [4]约翰·霍普金斯.感染性疾病的诊断与治疗[M].北京:科学技术文献出版社,2012:85-106. [5]Solomkin JS,Mazuski JE,Bradley JS,et al.Diagnosis and management of complicated intra-abdominal infection in adults and children:guidelines by the Surgical Infection Society and the Infectious Diseases Society of America[J].Clinical Infectious Disease,2010,50(2): 133-164. [6]Sartelli M,Malangoni MA,May AK,et al.World Society of Emergency Surgery(WSES)guidelines for management of skin and soft tissue infections[J].World J Emerg Surg,2014,9(1):57. [7]国家卫生计生委办公厅,国家中医药管理局办公室,解放军总后勤部卫生部药品器材局.抗菌药物临床应用指导原则(2015年版)[Z].国卫办医发[2015]43号. [8]中华医学会呼吸病学分会.中国成人社区获得性肺炎诊断和治疗指南(2016年版)[J].中华结核和呼吸杂志,2016,39(4):1-27. [9]缪晓辉,冉陆,张文宏,等.成人急性感染性腹泻诊疗专家共识[J].中华消化杂志，2013,33(12):793-802 [10]Andi L. Shane MD et al. 2017 Infectious Disease Society of America Clinical Practice Guideline for the Diagnosis and Management of Infectious Diarrhea[J].Clinical Infectious Diseases,2017,65 (12):1963-1973. [11]彭小林,范亚新,张亮,等.氨基糖苷类抗生素治疗药物浓度监测的研究进展[J].中国感染与化疗杂志,2017,17(1):104-109.

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更新日期/Last Update: 2018-11-20