[1]王 蕊,陈金萍.2016~2017年脊柱手术预防用药及术后感染情况分析[J].医学信息,2018,31(24):112-114.[doi:10.3969/j.issn.1006-1959.2018.24.032]
　WANG Rui,CHEN Jin-ping.Analysis of Orophylactic Medication and Postoperative Infection in Spinal Surgery from 2016 to 2017[J].Journal of Medical Information,2018,31(24):112-114.[doi:10.3969/j.issn.1006-1959.2018.24.032]
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2016~2017年脊柱手术预防用药及术后感染情况分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年24期
页码:
112-114
栏目:
调查分析
出版日期:
2018-12-15

文章信息/Info

Title:
Analysis of Orophylactic Medication and Postoperative Infection in Spinal Surgery from 2016 to 2017
文章编号:
1006-1959（2018）24-0112-03
作者:
王 蕊; 陈金萍
首都医科大学石景山教学医院药剂科，北京 100043
Author(s):
WANG Rui; CHEN Jin-ping
Department of Pharmacy,Shijingshan Teaching Hospital,Capital Medical University,Beijing 100043,China
关键词:
抗菌药物; 预防用药; 感染; 脊柱手术
Keywords:
Antibacterial agent Prophylactic antibiotics Infection
分类号:
R473.6
DOI:
10.3969/j.issn.1006-1959.2018.24.032
文献标志码:
A
摘要:
目的 分析我院脊柱手术抗菌药物预防使用情况，为临床合理用药提供依据。方法 选择2016年1月~2017年12月在我院进行脊柱手术的患者100例，根据预防用药时间分为观察组63例和对照组37例，记录切口大小、手术时间、术中出血量、住院天数、术后CRP、PCT及感染诊断。结果 观察组手术平均预防用药时间为（6.11±2.96）d。观察组与对照组的切口大小、术中出血量比较，差异无统计学意义（P＞0.05）；手术时间、住院天数观察组高于住院组，差异有统计学意义（P＜0.05）；两组手术感染率比较，差异无统计学意义（P＞0.05）。结论 延长抗菌药物预防用药时间对于降低术后感染的发生并没有更多优势；可通过监测CRP、PCT及综合评估是否发生术后感染。
Abstract:
Objective To analyze the prophylactic use of antimicrobial agents in spinal surgery in our hospital and to provide evidence for rational use of antibiotics in clinic.Methods 100 patients undergoing spinal surgery in our hospital from January 2016 to December 2017 were selected.According to whether the time of prophylactic medication was longer than 24 h,they were divided into observation group (n=63) and control group (n=37). The incision size, operation time, intraoperative bleeding, hospital stay, postoperative CRP,PCT and infection diagnosis were recorded.Results The average prophylaxis time of the observation group was (6.11±2.96)d. There was no significant difference in the size of incision and intraoperative blood loss between the observation group and the control group (P>0.05). The operation time and hospitalization days were higher in the observation group than in the inpatient group, and the difference was statistically significant(P<0.05). There was no significant difference in the surgical infection rate between the two groups(P>0.05). Conclusion Prolonging the time of antibiotic prophylaxis has no more advantages in reducing the incidence of postoperative infection. It can be evaluated by monitoring CRP, PCT and comprehensively to determine whether postoperative infection has occurred.

参考文献/References:

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更新日期/Last Update: 2019-01-09