[1]祖 赛,窦志杰,卢丹丹,等.非急性脑卒中患者脑白质疏松程度与 血尿酸水平的相关性研究[J].医学信息,2018,31(05):101-102.[doi:10.3969/j.issn.1006-1959.2018.05.033]
　ZU Sai,DOU Zhi-jie,LU Dan-dan,et al.Study on the Correlation between the Degree of Leukoaraiosis and the Level of Blood Uric Acid in Patients with non Acute Stroke[J].Journal of Medical Information,2018,31(05):101-102.[doi:10.3969/j.issn.1006-1959.2018.05.033]
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非急性脑卒中患者脑白质疏松程度与 血尿酸水平的相关性研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年05期
页码:
101-102
栏目:
临床研究
出版日期:
2018-03-01

文章信息/Info

Title:
Study on the Correlation between the Degree of Leukoaraiosis and the Level of Blood Uric Acid in Patients with non Acute Stroke
文章编号:
1006-1959（2018）05-0101-03
作者:
祖 赛1; 窦志杰2; 卢丹丹3; 宋冰冰1; 王 佩3
1.承德医学院，河北 承德 067000；2.承德医学院附属医院神经内科，河北 承德 067000； 3.保定市第一中心医院，河北 保定 071000
Author(s):
ZU Sai1; DOU Zhi-jie2; LU Dan-dan3; SONG Bing-bing1; WANG Pei3
1.Chengde Medical College,Chengde 067000,Hebei,China; 2.Department of Neurology,Affiliated Hospital of Chengde Medical College,Chengde 067000,Hebei,China; 3.Baoding First Central Hospital,Baoding 071000,Hebei,China
关键词:
尿酸; 脑白质疏松; 脑血管病
Keywords:
Key words：Uric acid; Leukoaraiosis; Cerebrovascular disease
分类号:
R743
DOI:
10.3969/j.issn.1006-1959.2018.05.033
文献标志码:
A
摘要:
目的 探讨非急性脑卒中患者的血尿酸水平与脑白质疏松程度之间的相关性。方法 选择2016年4月~2017年3月在承德医学院附属医院神经内科住院的存在脑白质疏松的患者123例，上述患者均为非急性脑卒中患者，收集所有患者临床资料，包括：Aharon-peretz量表评分、尿酸及其它实验室化验指标，并进行统计学分析。结果 无-轻度脑白质疏松组与中-重度脑白质疏松组患者的尿酸水平存在显著差异（P＜0.05）。经多因素Logistic回归分析，尿酸是脑白质疏松的独立危险因素[OR值1.007，95%可信区间1.002-1.012，P=0.004]。结论 在非急性脑卒中患者中，脑白质疏松程度越高，其体内尿酸水平也越高。
Abstract:
Abstract：Objective To investigate the correlation between serum uric acid level and the degree of leukoaraiosis in non-acute stroke patients.Methods 123 patients with leukoaraiosis were selected from April 2016 to March 2017 in Department of Neurology, Chengde medical college affiliated hospital.All of the above patients were non-acute stroke patients.All the clinical data were collected,including the score of the:Aharon-peretz scale,uric acid and other laboratory indexes and the statistical analysis was carried out.Results There was significant difference in uric acid level between non-mild leukoaraiosis group and moderate to severe leukoaraiosis group(P<0.05).By multivariate Logistic regression analysis,uric acid was an independent risk factor for leukoaraiosis[OR value 1.007,95% confidence interval 1.002-1.012,P=0.004].Conclusion n patients with non-acute stroke,the higher the degree of white matter degeneration,the higher the uric acid level in the body.

参考文献/References:

[1]Hachinski VC,Potter P,Merskey H.Leuko-araiosis.Arch Neurol[J].1987,44(1):21-23. [2]中华医学会神经病学分会,中华医学会神经病学分会脑血管病学组.中国脑小血管病诊治共识[J].中华神经科杂志,2015,48(10):838-844. [3]许寅宏,徐恩,林清原,等.脑梗死患者血清尿酸水平与颈动脉粥样硬化斑块危险因素的关系[J].中华老年心脑血管病杂志,2014,16(11):1124-1126.

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更新日期/Last Update: 2018-03-01