[1]苗艳茹.甲巯咪唑与糖皮质激素联合治疗甲状腺功能亢进症合并症的效果分析[J].医学信息,2018,31(05):136-137.[doi:10.3969/j.issn.1006-1959.2018.05.048]
　MIAO Yan-ru.Analysis of Effects of Methimazole and Glucocorticoids on Complications of Hyperthyroidism[J].Journal of Medical Information,2018,31(05):136-137.[doi:10.3969/j.issn.1006-1959.2018.05.048]
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甲巯咪唑与糖皮质激素联合治疗甲状腺功能亢进症合并症的效果分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年05期
页码:
136-137
栏目:
药物与临床
出版日期:
2018-03-01

文章信息/Info

Title:
Analysis of Effects of Methimazole and Glucocorticoids on Complications of Hyperthyroidism
文章编号:
1006-1959（2018）05-0136-02
作者:
苗艳茹
辽宁省绥中县医院内分泌科，辽宁 绥中 125200
Author(s):
MIAO Yan-ru
Department of Endocrinology,Suizhong County Hospital,Suizhong 125200,Liaoning,China
关键词:
甲状腺功能亢进症合并症; 甲巯咪唑; 糖皮质激素
Keywords:
Key words：Hyperthyroidism complication; Methimazole; Glucocorticoid
分类号:
R581.1
DOI:
10.3969/j.issn.1006-1959.2018.05.048
文献标志码:
A
摘要:
目的 分析甲巯咪唑与糖皮质激素联合治疗甲状腺功能亢进症合并症的临床效果。方法 收集我院2016年3月~2017年3月收治的130例甲状腺功能亢进症合并症患者作为研究对象，随机分为A组和B组，每组65例，A组采用甲巯咪唑治疗，B组采用甲巯咪唑与糖皮质激素联合治疗。对比两组患者临床疗效以及肝功能情况。结果 B组患者治疗总有效率53.85%高于A组患者的35.38%， 差异有统计学意义（P＜0.05）。治疗后两组患者丙氨酸氮基转氨酶和天门冬氨酸基转氨低于治疗前，差异有统计学意义（P＜0.05）。B组患者治疗后丙氨酸氮基转氨酶和天门冬氨酸基转氨低于A组，差异有统计学意义（P＜0.05）。结论 甲巯咪唑与糖皮质激素联合治疗甲状腺功能亢进症合并症效果良好，能促进患者肝功能改善，加速患者恢复，因此可进行临床推广应用。
Abstract:
Abstract：Objective To analyze the clinical effect of methimazole and glucocorticoids in the treatment of hyperthyroidism complications.Methods A total of 130 cases of hyperthyroidism comorbidities treated in our hospital from March 2016 to March 2017 were collected and randomly divided into group A and group B,with 65 cases in each group.Group A was treated with methimazole. Group B was treated with methimazole and glucocorticoids.The clinical efficacy and liver function of the two groups were compared. Results The total effective rate of treatment in group B was 53.85%,which was higher than that in group A 35.38%,the difference was statistically significant(P<0.05).After treatment,alanine aminotransferase and aspartate aminotransferase were lower than before treatment in the two groups,the difference was statistically significant(P<0.05).Group B of patients after treatment of alanine aminotransferase and aspartate amino transaminase is lower than the group A,the difference was statistically significant(P<0.05). Conclusion Methimazole combined with glucocorticoids in the treatment of hyperthyroidism complications with good effect,can promote liver function improvement,accelerate the recovery of patients,it can be carried out in clinical application.

参考文献/References:

[1]李党生.甲巯咪唑联合比索洛尔治疗甲状腺功能亢进症的临床效果分析[J].中国当代医药,2013,24(3):97-98. [2]曲欣旭.甲巯咪唑联合心得安治疗120例甲状腺功能亢进症的临床疗效评价[J].航空航天医学杂志,2015,12(2):1514-1515. [3]王璐璐.甲巯咪唑联合左甲状腺素治疗儿童甲状腺功能亢进症的临床效果分析[J].中国现代药物应用,2016,7(5):110-111. [4]廖萍.小剂量甲巯咪唑联合普萘洛尔治疗甲状腺功能亢进症的疗效分析[J].海峡药学,2015, 27(12):208-209.

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更新日期/Last Update: 2018-03-01