[1]江启煜,何晓华,刘秀峰,等.中药生物分子信息文献系统的研发与应用[J].医学信息,2019,32(15):10-13.[doi:10.3969/j.issn.1006-1959.2019.15.004]
　JIANG Qi-yu,HE Xiao-hua,LIU Xiu-feng,et al.Development and Application of Traditional Chinese Medicine Biomolecular Information Document System[J].Journal of Medical Information,2019,32(15):10-13.[doi:10.3969/j.issn.1006-1959.2019.15.004]
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中药生物分子信息文献系统的研发与应用()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年15期
页码:
10-13
栏目:
出版日期:
2019-08-01

文章信息/Info

Title:
Development and Application of Traditional Chinese Medicine Biomolecular Information Document System
文章编号:
1006-1959（2019）15-0010-04
作者:
江启煜; 何晓华; 刘秀峰; 刘慧玲; 王庆香
广州中医药大学，广东 广州 510405
Author(s):
JIANG Qi-yu; HE Xiao-hua; LIU Xiu-feng; LIU Hui-ling; WANG Qing-xiang
Guangzhou University of Traditional Chinese Medicine,Guangzhou 510405,Guangdong,China
关键词:
中药; 生物信息; 文献系统; 大数据
Keywords:
Key words：Traditional Chinese medicine; Biological information; Literature system; Big data
分类号:
R285
DOI:
10.3969/j.issn.1006-1959.2019.15.004
文献标志码:
A
摘要:
随着中医药药理实验和生命科学研究的不断发展，中药从宏观到微观层次已经积累了大量的实验数据以及文献信息，通过整合这些大数据，研发中药生物分子信息文献系统，具有重要意义。中药生物分子信息文献系统可以实现“中药-化学成份-靶蛋白-生物通路-文献信息”的多层次信息检索功能，并且具有蛋白基因关联知识推理发现功能，能够方便研究人员获取中药的所有相关化学成份、靶点、以及生物通路等数据信息，从而有助于分析中药对疾病的分子作用机制，而且系统的推理功能能够分析出两个或多个靶点之间的相互作用关联路径，使研究人员进一步探索多靶点之间的机制作用途径。
Abstract:
Abstract：With the continuous development of traditional Chinese medicine pharmacology experiments and life science research, Chinese medicine has accumulated a large amount of experimental data and literature information from the macro to the micro level. It is of great significance to integrate the big data and develop the biomolecular information literature system of traditional Chinese medicine. The traditional Chinese medicine biomolecular information literature system can realize the multi-level information retrieval function of "Chinese medicine-chemical composition-target protein-biological pathway-document information", and has the function of protein gene-related knowledge reasoning and discovery, which can facilitate researchers to obtain all relevant chemistry of traditional Chinese medicine. Data information such as components, targets, and biological pathways, which help to analyze the molecular mechanism of Chinese medicine on disease, and the system's reasoning function can analyze the interaction path between two or more targets, making research The personnel further explored the mechanism of action between multiple targets.

参考文献/References:

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更新日期/Last Update: 2019-08-01