[1]曾 庆,陆嘉惠,周永明.地西他滨治疗骨髓增生异常综合征研究进展[J].医学信息,2019,32(09):32-34.[doi:10.3969/j.issn.1006-1959.2019.09.011]
 ZENG Qing,LU Jia-hui,ZHOU Yong-ming.Progress in the Study of Decitabine in the Treatment of Myelodysplastic Syndrome[J].Journal of Medical Information,2019,32(09):32-34.[doi:10.3969/j.issn.1006-1959.2019.09.011]
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地西他滨治疗骨髓增生异常综合征研究进展()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年09期
页码:
32-34
栏目:
综述
出版日期:
2019-05-01

文章信息/Info

Title:
Progress in the Study of Decitabine in the Treatment of Myelodysplastic Syndrome
文章编号:
10.3969/j.issn.1006-1959.2019.09.032
作者:
曾 庆1陆嘉惠2周永明1
(1.上海中医药大学附属岳阳中西医结合医院血液内科,上海 200437;2. 上海中医药大学附属市中医医院,上海 200071)
Author(s):
ZENG Qing1LU Jia-hui2ZHOU Yong-ming1
(1.Department of Hematology,Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 200437,China;2.Chinese Medicine Hospital Affiliated to Shanghai University of Traditional Chin
关键词:
骨髓增生异常综合征地西他滨去甲基化治疗
Keywords:
Myelodysplastic syndromeDecitabineDemethylation therapy
分类号:
R733.7;R551.3
DOI:
10.3969/j.issn.1006-1959.2019.09.011
文献标志码:
A
摘要:
目前去甲基化药物地西他滨(DAC)治疗骨髓增生异常综合征(MDS)的疗效已得到普遍认可且已广泛应用于临床。本文简述其治疗作用机制及近年DAC对不同分型MDS治疗及其剂量、联合用药、分子学标志物预测、不良反应,总结现有临床及实验研究资料,为今后的精准用药治疗提供经验及参考。
Abstract:
The efficacy of the demethylating drug decitabine (DAC) in the treatment of myelodysplastic syndrome (MDS) has been widely recognized and widely used in clinical practice. This article briefly describes its therapeutic mechanism and recent DAC treatment of different types of MDS and its dose, combination, molecular marker prediction, adverse reactions, summarizing existing clinical and experimental research data, providing experience for future accurate drug treatment and reference.

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更新日期/Last Update: 2019-05-01