[1]郑小娟,阮建波.东莞虎门地区泌尿生殖道支原体感染及对四环素类药物耐药变化分析[J].医学信息,2020,33(13):145-147.[doi:10.3969/j.issn.1006-1959.2020.13.043]
　ZHENG Xiao-juan,RUAN Jian-bo.Analysis of Urogenital Mycoplasma Infection and Resistance to Tetracycline in Humen Area of Dongguan[J].Medical Information,2020,33(13):145-147.[doi:10.3969/j.issn.1006-1959.2020.13.043]
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东莞虎门地区泌尿生殖道支原体感染及对四环素类药物耐药变化分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年13期
页码:
145-147
栏目:
调查分析
出版日期:
2020-07-01

文章信息/Info

Title:
Analysis of Urogenital Mycoplasma Infection and Resistance to Tetracycline in Humen Area of Dongguan
文章编号:
1006-1959（2020）13-0145-03
作者:
郑小娟; 阮建波
（暨南大学附属东莞医院皮肤科，广东 东莞 523905）
Author(s):
ZHENG Xiao-juan; RUAN Jian-bo
(Department of Dermatology,Dongguan Hospital Affiliated to Jinan University,Dongguan 523905,Guangdong,China)
关键词:
支原体感染; 四环素类; 耐药性; 泌尿生殖道
Keywords:
Mycoplasma infection; Tetracyclines; Drug resistance; Urogenital tract
分类号:
R714.258
DOI:
10.3969/j.issn.1006-1959.2020.13.043
文献标志码:
A
摘要:
目的 了解东莞虎门地区泌尿生殖道支原体感染及对四环素类抗菌药物的耐药变化情况，为临床用药和防治提供参考。方法 选取2011年、2015年及2018年暨南大学附属东莞医院50074例支原体感染和药敏结果进行回顾性统计分析。结果 50074份患者标本中，支原体阳性标本22511份，总检出率为44.96%；不同年份支原体总检出率、解脲脲原体（Uu）检出率、人型支原体（Mh）检出率、Uu+Mh检出率比较，差异有统计学意义（P＜0.05）。其中支原体感染以单纯Uu感染为主，其次为Uu+Mh感染、Mh感染。22511例阳性标本中女性20177份，男性2334份，女性总检出率高于男性总检出率，差异有统计学意义（P＜0.05）；男性与女性不同年份支原体检出率比较，差异有统计学意义（P＜0.05），送检的阳性标本中年龄主要集中于21~30岁，以女性居多。2011年、2015年和2018年四环素类药物药敏结果显示，多西环素耐药率分别为5.59%、3.50%和3.20%，米诺环素耐药率分别为4.89%、2.60%和1.20%，均呈下降趋势（P＜0.05）。结论 东莞虎门地区泌尿生殖道支原体感染检出率呈下降趋势，对四环素药物耐药率低，可作为本地区支原体感染的首选药物。
Abstract:
Objective To understand the infection of urogenital mycoplasma and resistance to tetracycline antibiotics in Humen area of Dongguan, and to provide reference for clinical medication and prevention.Methods Retrospective statistical analysis was performed on 50074 cases of mycoplasma infection and drug sensitivity in Dongguan Hospital Affiliated to Jinan University in 2011, 2015 and 2018.Results Of the 50074 patient samples, 22511 were positive for Mycoplasma, with a total detection rate of 44.96%; the total detection rate of Mycoplasma in different years, the detection rate of Ureaplasma urealyticum (Uu), the detection rate of Mycoplasma hominis (Mh), Uu+Mh detection rate comparison, the difference was statistically significant (P<0.05). Mycoplasma infection is mainly Uu infection, followed by Uu+Mh infection and Mh infection. Among 22,511 positive specimens, there were 20177 females and 2334 males. The total detection rate of females was higher than that of males,the difference was statistically significant (P<0.05); The detection rate of mycoplasma in males and females in different years was statistically significant (P<0.05). The age of the positive specimens sent to the test was mainly 21 to 30 years old, and most of them were females. The susceptibility results of tetracycline drugs in 2011, 2015 and 2018 showed that the resistance rates of doxycycline were 5.59%, 3.50% and 3.20%, respectively, and the resistance rates of minocycline were 4.89%, 2.60% and 1.20%,respectively,showing a downward trend (P<0.05).Conclusion The detection rate of urogenital mycoplasma infection in Humen area of Dongguan is declining, and the drug resistance rate to tetracycline is low. It can be used as the first choice for mycoplasma infection in this area.

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更新日期/Last Update: 1900-01-01