[1]油文静,朱 锋,汪 漩,等.不同机械通气模式对呼吸机相关性膈肌功能障碍的影响[J].医学信息,2020,33(16):110-111.[doi:10.3969/j.issn.1006-1959.2020.16.033]
　YOU Wen-jing,ZHU Feng,WANG Xuan,et al.Effects of Different Mechanical Ventilation Modes on Ventilator-related Diaphragmatic Muscle Dysfunction[J].Medical Information,2020,33(16):110-111.[doi:10.3969/j.issn.1006-1959.2020.16.033]
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不同机械通气模式对呼吸机相关性膈肌功能障碍的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年16期
页码:
110-111
栏目:
临床研究
出版日期:
2020-08-15

文章信息/Info

Title:
Effects of Different Mechanical Ventilation Modes on Ventilator-related Diaphragmatic Muscle Dysfunction
文章编号:
1006-1959（2020）16-0110-02
作者:
油文静; 朱 锋; 汪 漩; 等
（上海市杨浦区中心医院重症医学科，上海 200090）
Author(s):
YOU Wen-jing; ZHU Feng; WANG Xuan; et al
(Department of Critical Care Medicine,Shanghai Yangpu District Central Hospital,Shanghai 200090,China)
关键词:
机械通气; 呼吸机相关性膈肌功能障碍; ICU; 丙二醛
Keywords:
Mechanical ventilation; Ventilator-related diaphragmatic dysfunction; ICU; Malondialdehyde
分类号:
R56
DOI:
10.3969/j.issn.1006-1959.2020.16.033
文献标志码:
A
摘要:
目的 比较不同机械通气模式对下腹部外科手术后患者呼吸机相关性膈肌功能障碍的影响。方法 选取2017年3月~2019年6月我院ICU收治的接受有创机械通气治疗的下腹部外科手术患者120例作为研究对象，按照通气模式将其分为对照组（n=60）和观察组（n=60），对照组行定压控制通气，观察组行神经调节辅助通气，比较两组ICU入住时间、机械通气时间、治疗后氧化应激指标水平以及人机同步性指标水平。结果 观察组ICU入住时间、机械通气时间均短于对照组，差异有统计学意义（P＜0.05）；观察组超氧化物歧化酶（SOD）、谷胱甘肽（GSH）水平高于对照组，差异有统计学意义（P＜0.05）；观察组丙二醛（MDA）低于对照组，差异有统计学意义（P＜0.05）；观察组人机同步性各项评价指标水平均低于对照组，差异有统计学意义（P＜0.05）。结论 对下腹部外科术后患者行神经调节辅助通气可促使患者人机同步性提升，减少氧化应激反应、ICU入住时间以及机械通气时间，减少呼吸机相关性膈肌功能障碍的发生。
Abstract:
Objective To compare the effects of different mechanical ventilation modes on patients with ventilator-related diaphragmatic dysfunction after lower abdominal surgery.Methods A total of 120 patients undergoing invasive mechanical ventilation in the lower abdomen surgery who were admitted to the ICU of our hospital from March 2017 to June 2019 were selected as the research objects. According to the ventilation mode, they were divided into a control group (n=60) and an observation group (n=60), the control group received constant pressure controlled ventilation, and the observation group received neuromodulation assisted ventilation. The two groups were compared with ICU stay time, mechanical ventilation time, oxidative stress index level after treatment, and man-machine synchronization index level.Results The ICU stay time and mechanical ventilation time of the observation group were shorter than those of the control group,the difference was statistically significant (P＜0.05); the levels of superoxide dismutase (SOD) and glutathione (GSH) in the observation group werehigher than the control group, the difference was statistically significant (P<0.05); The malondialdehyde (MDA) of the observation group was lower than that of the control group,the difference was statistically significant (P＜0.05); The evaluation index levels were lower than those of the control group,the difference was statistically significant (P<0.05).Conclusion Neuromodulation assisted ventilation for patients after lower abdominal surgery could improve the synchronization of patients and machines, reduce oxidative stress, ICU stay time and mechanical ventilation time, and reduce the occurrence of ventilator-related diaphragm dysfunction.

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更新日期/Last Update: 1900-01-01