[1]刘可文,周 浩.经脐单孔腹腔镜手术治疗急性胆囊炎患者的有效性及对血清淀粉酶水平的影响[J].医学信息,2020,33(24):93-96.[doi:10.3969/j.issn.1006-1959.2020.24.025]
　LIU Ke-wen,ZHOU Hao.The Effectiveness of Transumbilical Single Port Laparoscopic Surgery in Patients with Acute Cholecystitis and Its Effect on Serum Amylase Levels[J].Medical Information,2020,33(24):93-96.[doi:10.3969/j.issn.1006-1959.2020.24.025]
点击复制

经脐单孔腹腔镜手术治疗急性胆囊炎患者的有效性及对血清淀粉酶水平的影响()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年24期
页码:
93-96
栏目:
论著
出版日期:
2020-12-15

文章信息/Info

Title:
The Effectiveness of Transumbilical Single Port Laparoscopic Surgery in Patients with Acute Cholecystitis and Its Effect on Serum Amylase Levels
文章编号:
1006-1959（2020）24-0093-04
作者:
刘可文; 周 浩
上海市东方医院吉安医院普外科，江西 吉安 343000
Author(s):
LIU Ke-wen; ZHOU Hao
General Surgery,Shanghai East Hospital Ji’an Hospital,Ji’an 343000,Jiangxi,China
关键词:
经脐单孔腹腔镜手术; 急性胆囊炎; 血清淀粉酶
Keywords:
Transumbilical single-port laparoscopic surgery; Acute cholecystitis; Serum amylase
分类号:
R657.4+1
DOI:
10.3969/j.issn.1006-1959.2020.24.025
文献标志码:
A
摘要:
目的 探讨经脐单孔腹腔镜手术治疗急性胆囊炎患者的有效性及对血清淀粉酶水平的影响。方法 选取2018年1月~2019年11月我院收治的80例急性胆囊炎患者作为研究对象，按手术方法不同分为研究组和对照组，每组40例。对照组予以腹腔镜胆囊切除术治疗，研究组予以经脐单孔腹腔镜手术治疗，比较两组手术情况、血清淀粉酶（AMY）和血清脂多糖（LPS）水平、健康调查简表评分、术后并发症发生率、肝功能指标以及炎症反应指标。结果 研究组术中失血量、手术用时、术后疼痛时间、住院时间均少于对照组，下床活动时间早于对照组，差异有统计学意义（P＜0.05）；研究组AMY、LPS水平低于对照组，差异有统计学意义（P＜0.05）；研究组并发症总发生率为7.50%，低于对照组的27.50%，差异有统计学意义（P＜0.05）。研究组SF-36躯体疼痛、躯体功能、生命活力、精神健康评分高于对照组，差异有统计学意义（P＜0.05）；研究组术后C反应蛋白、白细胞计数、碱性磷酸酶、门冬氨酸氨基转移酶、谷丙转氨酶均优于对照组，差异有统计学意义（P＜0.05）。结论 经脐单孔腹腔镜手术治疗急性胆囊炎可有效减少患者术中失血量，缩短手术用时、术后疼痛时间、住院时间，降低血清淀粉酶、脂多糖水平及并发症发生率，提高患者的生活质量，保护患者肝功能。
Abstract:
Objective To investigate the effectiveness of transumbilical single port laparoscopic surgery in the treatment of patients with acute cholecystitis and its effect on serum amylase levels.Methods A total of 80 patients with acute cholecystitis admitted to our hospital from January 2018 to November 2019 were selected as the research objects. They were divided into study group and control group according to different surgical methods, with 40 cases in each group. The control group was treated with laparoscopic cholecystectomy, and the study group was treated with transumbilical single-port laparoscopic surgery. The operation conditions, serum amylase (AMY) and serum lipopolysaccharide (LPS) levels, health survey scores, and surgery were compared between the two groups. The incidence of post-complication, liver function indicators and inflammatory response indicators.Results Intraoperative blood loss, operation time, postoperative pain time, and hospital stay in the study group were less than those in the control group, and the time to get out of bed was earlier than the control group, the difference was statistically significant (P<0.05); the study group had low levels of AMY and LPS in control group, the difference was statistically significant (P<0.05); the total incidence of complications in the study group was 7.50%, which was lower than 27.50% in the control group,the difference was statistically significant (P<0.05). The scores of SF-36 physical pain, physical function, vitality, and mental health of the study group were higher than those of the control group,the difference was statistically significant (P<0.05); the study group had C-reactive protein, white blood cell count, alkaline phosphatase, gate both aspartate aminotransferase and alanine aminotransferase were better than the control group,the difference was statistically significant (P<0.05).Conclusion Transumbilical single port laparoscopic surgery for acute cholecystitis can effectively reduce intraoperative blood loss, shorten the operation time, postoperative pain, and hospital stay, reduce serum amylase, lipopolysaccharide levels and complication rates, and improve patients’ health Quality of life, protect the liver function of patients.

参考文献/References:

[1]张君,高洁,高东.腹腔镜胆囊切除术对患者胃肠功能与炎性指标的影响研究[J].贵州医药,2019,10(5):722-723. [2]王青峰,张明,汪源,等.腹腔镜下三孔法胆囊切除术治疗急性胆囊炎患者的临床疗效及手术指标观察[J].贵州医药,2018,17(9):152-153. [3]崔彭华,王会民,张玉娟,等.腹腔镜与开腹手术治疗对早期子宫内膜癌患者血清肿瘤标志物、凝血功能及免疫功能的影响[J].海南医学院学报,2017,23(15):2109-2112. [4]程廷涛,丁钧.PTCD联合腹腔镜胆囊切除术治疗急性胆囊炎患者的疗效分析[J].重庆医学,2019,14(6):1058-1061. [5]Zhang WF,Li ZT,Fang JJ,et al.Expression and clinical significance of rhubarb on serum amylase and TNF-alpha of rat model of acute pancreatitis[J].J Biol Regul Homeost Agents,2017,31(3):753-760. [6]杨青松,张文俊.腹腔镜胆囊切除术治疗急性胆囊炎中转为开腹手术的危险因素分析[J].安徽医学,2018,40(7):196-197. [7]杨海宁,冶秀花.腹腔镜手术治疗急性胆囊炎的疗效及对血清细胞间黏附分子-1,人基质金属蛋白酶-9和血管内皮生长因子的影响[J].临床外科杂志,2018,26(10):780-782. [8]王新宁,卜震.应用腹腔镜治疗急性胆囊炎的手术时机及其对临床疗效的影响[J].江苏医药,2018,15(5):129-130. [9]刘超,孙艳军,刘莉.腹腔镜胆囊切除术治疗胆囊颈部结石嵌顿合并急性胆囊炎的临床研究[J].安徽医药,2017,21(10):1823-1825. [10]Zhang H,Liu W,Han X,et al.Effect of Laparoscopic Roux-en-Y Gastric Bypass Surgery on Thyroid Hormone Levels in Chinese Patients, Could It Be a Risk for Thyroid Nodules[J].Obesity Surgery,2017,27(1):2619-2627. [11]李泉,张程鹏.老年急性胆囊炎经不同时机腹腔镜胆囊切除术治疗的临床疗效观察[J].贵州医药,2019,43(5):263-264. [12]周健,高淳,唐学典.腹腔镜胆囊切除术治疗老年急性坏疽性胆囊炎对机体免疫功能的影响[J].河北医药,2016,38(23):285-286. [13]沈学艺,陈宇峰,李政,等.经皮经肝胆囊穿刺置管引流术后胆囊不同切除时机对急性胆囊炎手术效果的影响[J].现代消化及介入诊疗,2019(A02):2362-2362. [14]许良,许明友,杨先芬.老年急性胆囊炎开腹胆囊切除与腹腔镜胆囊切除术的治疗效果对比及对患者肠道功能影响分析[J].安徽医药,2018,22(4):721-724. [15]陶平,吴向阳,张磊.超声引导经皮经肝胆囊穿刺引流术治疗老年急性胆囊炎的效果分析[J].临床肝胆病杂志,2016,32(10):1929-1931.

相似文献/References:

[1]陈晓东,乔阳波,周 伟.腹腔镜胆囊切除术治疗急性胆囊炎并发胆结石患者的效果[J].医学信息,2023,36(06):139.[doi:10.3969/j.issn.1006-1959.2023.06.030]
　CHEN Xiao-dong,QIAO Yang-bo,ZHOU Wei.Effect of Laparoscopic Cholecystectomy on Patients with Acute Cholecystitis Complicated with Gallstones[J].Medical Information,2023,36(24):139.[doi:10.3969/j.issn.1006-1959.2023.06.030]

更新日期/Last Update: 1900-01-01