[1]尚子祥,李 锐.老年胃肠道手术患者术后谵妄的危险因素分析[J].医学信息,2021,34(05):107-110.[doi:10.3969/j.issn.1006-1959.2021.05.030]
 SHANG Zi-xiang,LI Rui.Analysis of Risk Factors for Postoperative Delirium in Elderly Patients Undergoing Gastrointestinal Surgery[J].Medical Information,2021,34(05):107-110.[doi:10.3969/j.issn.1006-1959.2021.05.030]
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老年胃肠道手术患者术后谵妄的危险因素分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年05期
页码:
107-110
栏目:
论著
出版日期:
2021-03-01

文章信息/Info

Title:
Analysis of Risk Factors for Postoperative Delirium in Elderly Patients Undergoing Gastrointestinal Surgery
文章编号:
1006-1959(2021)05-0107-04
作者:
尚子祥李 锐
(1.安徽医科大学第二附属医院麻醉与围术期医学科,安徽 合肥 230601; 2.安徽医科大学麻醉与围术期医学安徽普通高校重点实验室,安徽 合肥 230601)
Author(s):
SHANG Zi-xiangLI Rui
(1.Department of Anesthesia and Perioperative Medicine,the Second Affiliated Hospital of Anhui Medical University, Hefei 230601,Anhui,China; 2.Key Laboratory of Anesthesia and Perioperative Medicine of Anhui Higher Education Institutes,Anhui Medical Unive
关键词:
胃肠道手术术后谵妄老年患者危险因素
Keywords:
Gastrointestinal surgeryPostoperative deliriumElderly patientsRisk factors
分类号:
R61
DOI:
10.3969/j.issn.1006-1959.2021.05.030
文献标志码:
A
摘要:
目的 研究老年胃肠道手术患者术后谵妄(POD)相关的危险因素。方法 前瞻性观察我院2018年9月~2019年12月在全身麻醉下接受胃肠道手术的老年患者230例,术后根据中文修订版谵妄诊断量表(CAM-CR)评估结果,将患者分为POD组(52例)和非POD组(178例)。比较两组患者的围术期资料,分析患者发生POD的相关危险因素。结果 两组患者性别、BMI、ASA分级(Ⅱ级、Ⅲ级)、平均动脉压、吸烟史、高血压、糖尿病、心脏病、手术麻醉史、BIS最低值、输液量、尿量、失血量、术中输血比较,差异无统计学意义(P>0.05);两组患者年龄、MMSE评分、脑卒中史、术中低血压、手术时间、麻醉时间、入恢复室VAS评分比较,差异有统计学意义(P<0.05);多因素logistic回归分析结果显示,年龄、脑卒中史、术中低血压、麻醉时间和术后VAS评分是老年胃肠道手术患者术后发生谵妄的独立危险因素(P<0.05)。结论 高龄、脑卒中史、术中低血压、麻醉时间长和术后疼痛是老年胃肠道手术患者发生术后谵妄的独立危险因素。
Abstract:
Objective To study the risk factors of postoperative delirium (POD) in elderly patients undergoing gastrointestinal surgery.Methods Prospectively observe 230 elderly patients who underwent gastrointestinal surgery under general anesthesia in our hospital from September 2018 to December 2019.After the operation, the patients were divided into POD group (52 cases) and non-POD group (178 cases) according to the evaluation results of the Chinese revised version of the Diagnostic Scale for Delirium (CAM-CR).The perioperative data of the two groups of patients were compared, and the relevant risk factors for POD were analyzed.Results The two groups of patients were gender, BMI, ASA classification (Class II, Class III), mean arterial pressure, history of smoking, hypertension, diabetes, heart disease, history of surgical anesthesia, minimum BIS, volume of infusion, volume of urine, volume of blood loss,there was no significant difference in intraoperative blood transfusion (P>0.05);There was a statistically significant difference between the two groups of patients’ age, MMSE score, stroke history, intraoperative hypotension, operation time, anesthesia time, and VAS score in the recovery room (P<0.05);Multivariate logistic regression analysis showed that age, stroke history, intraoperative hypotension, anesthesia time, and postoperative VAS score were independent risk factors for delirium in elderly patients undergoing gastrointestinal surgery (P<0.05).Conclusion Old age, history of stroke, intraoperative hypotension, long anesthesia time, and postoperative pain are independent risk factors for postoperative delirium in elderly patients undergoing gastrointestinal surgery.

参考文献/References:

[1]Hebert C.Evidence-Based Practice in Perianesthesia Nursing:Application of the American Geriatrics Society Clinical Practice Guideline for Postoperative Delirium in Older Adults[J].J Perianesth Nurs,2018,33(3):253-264. [2]Bannon L,Mcgaughey J,Verghis R,et al.The effectiveness of non-pharmacological interventions in reducing the incidence and duration of delirium in critically ill patients:a systematic review and meta-analysis[J].Intensive Care Med,2019,45(1):1-12. [3]Rudolph JL,Marcantonio ER.Review articles:postoperative delirium: acute change with long-term implications[J].Anesth Analg,2011,112(5):1202-1211. [4]Scholz AF,Oldroyd C,Mccarthy K,et al.Systematic review and meta-analysis of risk factors for postoperative delirium among older patients undergoing gastrointestinal surgery[J].Br J Surg,2016,103(2):e21-e28. [5]Daiello LA,Racine AM,Yun GR,et al.Postoperative Delirium and Postoperative Cognitive Dysfunction:Overlap and Divergence[J].Anesthesiology,2019,131(3):477-491. [6]Marcantonio ER.Delirium in Hospitalized Older Adults[J].N Engl J Med,2018,378(1):96-97. [7]Chen YL,Lin HC,Lin KH,et al.Low hemoglobin level is associated with the development of delirium after hepatectomy for hepatocellular carcinoma patients[J].PLoS One,2015,10(3):e0119199. [8]Janssen TL,Steyerberg EW,Faes MC,et al.Risk factors for postoperative delirium after elective major abdominal surgery in elderly patients:A cohort study[J].Int J Surg,2019(71):29-35. [9]Neuro VI.Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION):a prospective cohort study[J].Lancet,2019,394(10203):1022-1029. [10]Hachinski V.Dementia:new vistas and opportunities[J].Neurol Sci,2019,40(4):763-767. [11]Eertmans W,Dedeyne C,Genbrugge C,et al.Association between postoperative delirium and postoperative cerebral oxygen desaturation in older patients after cardiac surgery[J].Br J Anaesth,2020,124(2):146-153. [12]郝亚楠,罗婷,吴安石.神经心理学测试在评价术后认知功能障碍中的应用进展[J].国际麻醉学与复苏杂志,2018,39(5):463-467. [13]Futier E,Lefrant JY,Guinot PG,et al.Effect of Individualized vs Standard Blood Pressure Management Strategies on Postoperative Organ Dysfunction Among High-Risk Patients Undergoing Major Surgery:A Randomized Clinical Trial[J].JAMA,2017,318(14):1346-1357. [14]Xu X,Hu X,Wu Y,et al.Effects of different BP management strategies on postoperative delirium in elderly patients undergoing hip replacement:A single center randomized controlled trial[J].J Clin Anesth,2020,(62):109730. [15]Maheshwari K,Ahuja S,Khanna AK,et al.Association Between Perioperative Hypotension and Delirium in Postoperative Critically Ill Patients:A Retrospective Cohort Analysis[J].Anesth Analg,2020,130(3):636-643. [16]Liu X,Yu Y,Zhu S.Inflammatory markers in postoperative delirium(POD)and cognitive dysfunction(POCD):A meta-analysis of observational studies[J].PLoS One,2018,13(4):e0195659. [17]Kawano T,Yamanaka D,Aoyama B,et al.Involvement of acute neuroinflammation in postoperative delirium-like cognitive deficits in rats[J].J Anesth,2018,32(4):506-517. [18]Chen W,Ke X,Wang X,et al.Prevalence and risk factors for postoperative delirium in total joint arthroplasty patients:A prospective study[J].Gen Hosp Psychiatry,2017(46):55-61.

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更新日期/Last Update: 1900-01-01