[1]陶仲宾,王 洁,杨亚玲.宝乐安辅助治疗儿童反复呼吸道感染继发性腹泻的临床疗效[J].医学信息,2021,34(05):158-160.[doi:10.3969/j.issn.1006-1959.2021.05.045]
　TAO Zhong-bin,WANG Jie,YANG Ya-ling.The Clinical Efficacy of Baolean in Adjuvant Treatment of Diarrhea Secondary to RecurrentRespiratory Infections in Children[J].Medical Information,2021,34(05):158-160.[doi:10.3969/j.issn.1006-1959.2021.05.045]
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宝乐安辅助治疗儿童反复呼吸道感染继发性腹泻的临床疗效()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年05期
页码:
158-160
栏目:
药物与临床
出版日期:
2021-03-01

文章信息/Info

Title:
The Clinical Efficacy of Baolean in Adjuvant Treatment of Diarrhea Secondary to RecurrentRespiratory Infections in Children
文章编号:
1006-1959（2021）05-0158-03
作者:
陶仲宾; 王 洁; 杨亚玲
（1.兰州大学第一医院儿科，甘肃 兰州 730000； 2.兰州市妇幼保健院新生儿科，甘肃 兰州 730030）
Author(s):
TAO Zhong-bin; WANG Jie; YANG Ya-ling
(1.Department of Pediatrics,the First Hospital of Lanzhou University,Lanzhou 730000,Gansu,China; 2.Department of Neonatology,Lanzhou Maternal and Child Health Hospital,Lanzhou 730030,Gansu,China)
关键词:
宝乐安; 儿童反复呼吸道感染; 继发性腹泻; 蒙脱石散
Keywords:
Baolean; Children with recurrent respiratory infections; Secondary diarrhea;  Montmorillonite powder
分类号:
R725.6
DOI:
10.3969/j.issn.1006-1959.2021.05.045
文献标志码:
A
摘要:
目的 探讨宝乐安辅助治疗儿童反复呼吸道感染继发性腹泻的临床效果。方法 选择2018年3月~2020年2月兰州大学第一医院儿科收治的120例反复呼吸道感染继发性腹泻患儿作为研究对象，随机分为研究组和对照组，各60例。对照组使用蒙脱石散治疗，研究组在此基础上加用宝乐安治疗，比较两组排便次数恢复正常时间、大便性状恢复正常时间、粪便实验室指标恢复正常时间、住院时间、退热时间、咽部充血缓解时间、流涕缓解时间、咳嗽缓解时间、C反应蛋白降至正常时间及治疗总有效率。结果 研究组排便次数恢复正常时间、大便性状恢复正常时间、粪便实验室指标恢复正常时间及住院时间、退热时间、咽部充血缓解时间、流涕缓解时间、咳嗽缓解时间以及C反应蛋白降至正常时间均少于对照组，差异有统计学意义（P＜0.05）；研究组治疗总有效率为93.33%，高于对照组的78.33%，差异有统计学意义（P＜0.05）。结论 宝乐安可改善反复呼吸道感染继发性腹泻患儿的腹泻及呼吸道感染症状，同时可提高反复呼吸道感染的治疗效果，值得临床应用。
Abstract:
Objective To explore the clinical effect of Baolean in adjuvant treatment of diarrhea secondary to recurrent respiratory infections in children.Methods From March 2018 to February 2020, 120 children with recurrent respiratory infections and secondary diarrhea admitted to the Department of Pediatrics of the First Hospital of Lanzhou University were selected as the research objects, and they were randomly divided into a study group and a control group, with 60 cases in each group.The control group was treated with montmorillonite powder, and the study group was treated with Baolean on this basis. The two groups were compared with the time when the number of bowel movements returned to normal.Stool traits return to normal time, stool laboratory indicators return to normal time, hospitalization time, antipyretic time, pharyngeal congestion remission time, runny nose remission time, cough remission time, C-reactive protein to normal time and the total effective rate of treatment.Results The time for the number of bowel movements in the study group to return to normal, the time to return to normal stool characteristics, the time to return to normal stool laboratory indicators and the length of hospital stay, the time to reduce fever, the time to relieve throat congestion,runny nose relief time, cough relief time, and C-reactive protein remission time were less than those of the control group,the difference was statistically significant (P<0.05);The total effective rate of treatment in the study group was 93.33%, which was higher than 78.33% in the control group,the difference was statistically significant (P<0.05).Conclusion Baolean can improve the symptoms of diarrhea and respiratory tract infection in children with recurrent respiratory tract infections and secondary diarrhea, and at the same time can improve the treatment effect of recurrent respiratory tract infections. It is worthy of clinical application.

参考文献/References:

[1]陈晓君,郭瑞娟,曾丽森.影响3~6岁儿童反复发生上呼吸道感染的相关因素分析[J].中国儿童保健杂志,2018,26(11):1244-1247. [2]戴毅华,叶明勇.酪酸梭菌二联活菌散治疗小儿肺炎继发性腹泻的效果分析[J].吉林医学,2019,40(2):257-258. [3]廖汇昌,赵珊珊,吴幼萍.口服酪酸梭菌二联活菌散剂和蒙脱石散剂联合治疗小儿肺炎继发性腹泻的临床疗效分析[J].中国现代药物应用,2015,9(14):126-127. [4]郑玲玲.中西医结合治疗小儿反复呼吸道感染疗效观察[J].中医临床研究,2019,11(21): 21-22. [5]李玲飞,童夏生,冯利平.中西医结合治疗小儿反复呼吸道感染30例[J].中国中医药科技,2019,26(3):395-396. [6]陈雪.益生菌对新生儿肺炎继发性腹泻的防治效果及其对胃肠功能的影响[J].实用心脑肺血管病杂志,2018,26(2):118-120. [7]曹亚男,丰立娟,王玉明.益生菌辅助治疗肠易激综合征的机制研究进展[J].中华消化杂志,2018(4):283-285. [8]熊祖明,袁杰利.酪酸梭菌的研究与应用进展[J].中国微生态学杂志,2011,23(12):1143-1145. [9]贺会学.小儿肺炎继发性腹泻的因素分析及其微生态制剂的预防作用研究[J].北方药学,2019,16(2):191-192. [10]Zeng J,Li TQ,Zuo XL,et al.Clinical trial:effect ofactive lactic acid bacteria on mucosal barrier function in patients with diarrhea predominant irritable bowel syndrome[J].Aliment Pharmaeol Ther,2008,28(9):994-1002. [11]周霁云.口服酪酸梭菌活菌散剂治疗儿童反复呼吸道感染疗效观察[J].实用中西医结合临床,2019,19(9):87-88. [12]季伟,赵德育,沈照波,等.酪酸梭菌588预防婴幼儿反复呼吸道感染多中心随机对照研究[J].儿科药学杂志,2015(4):13-17.

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更新日期/Last Update: 1900-01-01