[1]王 瑶.高压氧辅助治疗脑动脉硬化症患者的疗效[J].医学信息,2021,34(06):139-141.[doi:10.3969/j.issn.1006-1959.2021.06.036]
　WANG Yao.Efficacy of Hyperbaric Oxygen in the Treatment of Cerebral Arteriosclerosis Patients[J].Medical Information,2021,34(06):139-141.[doi:10.3969/j.issn.1006-1959.2021.06.036]
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高压氧辅助治疗脑动脉硬化症患者的疗效()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年06期
页码:
139-141
栏目:
临床研究
出版日期:
2021-03-15

文章信息/Info

Title:
Efficacy of Hyperbaric Oxygen in the Treatment of Cerebral Arteriosclerosis Patients
文章编号:
1006-1959（2021）06-0139-03
作者:
王 瑶
（天津市宝坻区人民医院神经内科，天津 301800）
Author(s):
WANG Yao
(Department of Neurology,People’s Hospital of Baodi District,Tianjin 301800,China)
关键词:
高压氧; 脑动脉硬化症; 血浆黏度
Keywords:
Hyperbaric oxygen; Cerebral arteriosclerosis; Plasma viscosity
分类号:
R743.1
DOI:
10.3969/j.issn.1006-1959.2021.06.036
文献标志码:
A
摘要:
目的 观察高压氧辅助治疗脑动脉硬化症患者的临床疗效。方法 选取2019年10月~2020年10月我院诊治的82例脑动脉硬化症患者为研究对象，采用随机数字表法分为对照组和观察组，各41例。对照组采用常规治疗，观察组在对照组基础上采用高压氧辅助治疗，比较两组临床治疗总有效率、临床症状评分、大脑动脉血流速度、血液流变学指标以及临床不良反应发生情况。结果 观察组治疗总有效率为92.68%，高于对照组的80.48%，差异有统计学意义（P＜0.05）。治疗后，观察组临床头痛、眩晕、失眠、记忆力下降评分均低于对照组，差异有统计学意义（P＜0.05）；两组大脑动脉血流速度均高于治疗前，且观察组高于对照组，差异有统计学意义（P＜0.05）；两组血浆黏度、全血高切黏度、全血低切黏度均低于治疗前，且观察组低于对照组，差异有统计学意义（P＜0.05）。观察组临床不良反应发生率为9.75%，与对照组的7.31%比较，差异无统计学意义（P＞0.05）。结论 高压氧辅助治疗脑动脉硬化症效果确切，可改善患者临床症状、降低血浆黏度、提高大脑动脉血流速度，且临床不良反应少，具有临床应用有效性和安全性。
Abstract:
Objective To observe the clinical curative effect of hyperbaric oxygen adjuvant therapy for patients with cerebral arteriosclerosis.Methods A total of 82 patients with cerebral arteriosclerosis who were diagnosed and treated in our hospital from October 2019 to October 2020 were selected as the research objects. They were divided into control group and observation group by random number table method, with 41 cases in each group.The control group was treated with conventional treatment, and the observation group was treated with hyperbaric oxygen adjuvant treatment on the basis of the control group. The total effective rate of clinical treatment, clinical symptom score, cerebral artery blood flow velocity, blood rheology index and occurrence of clinical adverse reactions were compared between the two groups.Results The total effective rate of treatment in the observation group was 92.68%, which was higher than 80.48% in the control group,the difference was statistically significant (P<0.05).After treatment, the scores of clinical headache, dizziness, insomnia, and memory decline in the observation group were lower than those in the control group,the difference was statistically significant (P<0.05);The cerebral arterial blood flow velocity of the two groups was higher than before treatment, and the observation group was higher than the control group, the difference was statistically significant (P<0.05);The two groups of plasma viscosity, whole blood high shear viscosity, whole blood low shear viscosity were lower than before treatment, and the observation group was lower than the control group, the difference was statistically significant (P<0.05).The incidence of clinical adverse reactions in the observation group was 9.75%, compared with 7.31% in the control group, the difference was not statistically significant (P>0.05).Conclusion The effect of hyperbaric oxygen in adjuvant treatment of cerebral arteriosclerosis is definite. It can improve patients’ clinical symptoms, reduce plasma viscosity, increase cerebral arterial blood flow velocity, and have fewer clinical adverse reactions. It has clinical application effectiveness and safety.

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更新日期/Last Update: 1900-01-01