[1]吕艳丽.联合高压氧治疗在创面修复中的应用研究[J].医学信息,2021,34(14):32-35.[doi:10.3969/j.issn.1006-1959.2021.14.009]
　LYU Yan-li.Study on the Application of Combined Hyperbaric Oxygen Therapy in Wound Healing[J].Medical Information,2021,34(14):32-35.[doi:10.3969/j.issn.1006-1959.2021.14.009]
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联合高压氧治疗在创面修复中的应用研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年14期
页码:
32-35
栏目:
综述
出版日期:
2021-07-15

文章信息/Info

Title:
Study on the Application of Combined Hyperbaric Oxygen Therapy in Wound Healing
文章编号:
1006-1959（2021）14-0032-04
作者:
吕艳丽
（天津市宝坻区人民医院神经内科，天津 301800）
Author(s):
LYU Yan-li
(Department of Neurology,Tianjin Baodi Hospital,Tianjin 301800,China)
关键词:
高压氧; 创面修复; 炎症反应; 细胞增殖
Keywords:
Hyperbaric oxygen; Wound repair; Inflammatory response; Cell proliferation
分类号:
R62
DOI:
10.3969/j.issn.1006-1959.2021.14.009
文献标志码:
A
摘要:
创面修复是临床常见问题，通常是由于外伤或其他伤病造成组织缺损后，局部组织通过再生、修复、重建，进行修复的一系列病理生理过程。如果创面愈合困难，急性创面会转化为慢性创面，不仅增加治疗难度，而且严重影响患者生活质量，并且会造成一定的经济和精神负担。目前，临床创面修复方法种类繁多，高压氧治疗（HBOT）作为一种新型治疗方法在创面修复中获得一定效果。本文就高压氧治疗概述及联合高压氧治疗创面修复的有效性和安全性作一综述，以期为临床创面修复提供一定的理论参考依据。
Abstract:
Wound repair is a common clinical problem. It is usually a series of pathophysiological processes in which local tissues undergo regeneration, repair, and reconstruction after tissue defects caused by trauma or other injuries.If the wound is difficult to heal, the acute wound will be transformed into a chronic wound, which will not only increase the difficulty of treatment, but also seriously affect the quality of life of the patient, and will cause a certain economic and spiritual burden.At present, there are a wide variety of clinical wound repair methods, and hyperbaric oxygen (HBOT) therapy as a new type of treatment has achieved certain results in wound repair.This article reviews the overview of hyperbaric oxygen therapy and the effectiveness and safety of combined hyperbaric oxygen therapy for wound repair, in order to provide a certain theoretical reference for clinical wound repair.

参考文献/References:

[1]曾宪忠,刘氜,李毅.高压氧治疗糖尿病足的疗效评价及对患者血清VEGF、bFGF水平的影响[J].中国现代医学杂志,2016,26(19):110-113. [2]蔡洁云,林博杰,潘新元,等.天然水蛭素联合高压氧治疗对大鼠随意皮瓣成活的影响研究[J].中国修复重建外科杂志,2018,32(4):484-490. [3]朱江英,殷国前,庞进军,等.高压氧预处理超长皮瓣组织血管内皮生长因子、转化生长因子β的表达[J].中国组织工程研究,2016,20(11):1525-1531. [4]Rajpal N,Walters ET,Elmarsafi T,et al.Use of hyperbaric oxygen therapy for tissue ischemia after breast reconstruction[J].Undersea Hyperb Med,2019,46(4):461-465. [5]何继东,伍晓华,刘莉,等.高压氧辅助治疗糖尿病足溃疡的系统评价[J].中国循证医学杂志,2014,14(12):1476-1481. [6]白登彦,张文贤.高压氧联合神经生长因子局部注射对骨质疏松性骨折延迟愈合患者血清黏附因子及微循环指标表达的影响[J].中国骨质疏松杂志,2019,25(9):1206-1211. [7]Wilson DF,Matschinsky FM.Hyperbaric oxygen toxicity in brain: A case of hyperoxia induced hypoglycemic brain syndrome[J].Med Hypotheses,2019(132):109375. [8]冯伟,潘新.高压氧治疗中耳气压伤的防范[J].中国医药指南,2018,16(32):101-102. [9]Hakkarainen T,Koivuniemi R,Kosonen M,et al.Nanofibrillar cellulose wound dressing in skin graft donor site treatment[J].J Control Release,2016,244(Pt B):292-301. [10]柳尧花,谭贵萍,王丽华.高压氧联合硫辛酸治疗糖尿病周围神经病变疗效观察[J].中华航海医学与高气压医学杂志,2016,23(4):298-301. [11]Padaki A,Reddy AP,Lehnhardt K.The utility of hyperbaric oxygen therapy for human spaceflight - Past, present, and future[J].Acta Astronautica,2019(164):192-196. [12]李雅娟,刘雪华,梁芳,等.高压氧预处理对皮瓣移植术后大鼠白介素-23的影响[J].中华物理医学与康复杂志,2015,37(8):571-574. [13]Lin SS,Yuan LJ,Niu CC,et al.Hyperbaric oxygen inhibits the HMGB1/RAGE signaling pathway by upregulating Mir-107 expression in human osteoarthritic chondrocytes[J].Osteoarthritis Cartilage,2019,27(9):1372-1381. [14]柳尧花,谭贵萍,王丽华.高压氧联合硫辛酸治疗糖尿病周围神经病变疗效观察[J].中华航海医学与高气压医学杂志,2016,23(4):298-301. [15]张鑫,廖志君.高压氧与GM-1联合应用于新生儿缺血缺氧性脑病中的效果及对患儿血清NSE、Bcl-2与NF-κB的影响[J].新疆医学,2019,49(1):46-48. [16]吴旭红,潘实,黄培颖.高压氧治疗糖尿病足患者相关临床指标的影响[J].中国实用医刊,2016,43(2):44-46. [17]Zhao H,Ge B,Yuan Y,et al.Hyperbaric Oxygen Ameliorated Acute Pancreatitis in Rats via the Mitochondrial Pathway[J].Dig Dis Sci,2020,65(12):3558-3569. [18]张文浩,吴起,马军,等.负压封闭引流联合肝素溶液治疗四肢深Ⅱ度烧伤创面的临床效果[J].中华烧伤杂志,2017,33(8):497-500. [19]刘学辉,薛朝亚,杨凯,等.负压封闭引流联合高压氧治疗难愈性创面效果观察[J].临床误诊误治,2018,31(11):96-100. [20]覃慧悦,陈欢.高压氧联合负压封闭引流治疗四肢创伤后感染性难愈合创面的疗效观察[J].中国临床新医学,2019,12(8):50-53. [21]Tejada S,Batle JM,Ferrer MD,et al.Therapeutic Effects of Hyperbaric Oxygen in the Process of Wound Healing[J].Curr Pharm Des,2019,25(15):1682-1693. [22]汪涛,赵珺,于敏,等.负压吸引疗法通过减轻炎症反应促进糖尿病足溃疡愈合[J].上海交通大学学报(医学版),2016,36(8):1159-1164. [23]Yu J,Lu S,McLaren AM,et al.Topical oxygen therapy results in complete wound healing in diabetic foot ulcers[J].Wound Repair Regen,2016,24(6):1066-1072. [24]王丽敏,刘诗博,郭大志,等.早期介入高压氧提高寒冷应激下小鼠存活率并促进创面愈合的研究[J].生物技术进展,2020,10(5):534-540. [25]朱鸣镝,赵林霞,高永静.高压氧治疗对小鼠慢性炎症性疼痛和组织水肿的影响[J].南通大学学报(医学版),2020,40(3):14-18. [26]解放军总医院第六医学中心,中国康复医学会高压氧康复专业委员会.高压氧在创面治疗中的应用专家共识(2018年)[J].中华航海医学与高气压医学杂志,2019,26(5):381-390. [27]金晶,陈育群,朱慧芬.负压封闭引流技术在糖尿病足溃疡治疗中的应用研究[J].浙江创伤外科,2014,19(6):981-982. [28]李哲.高压氧对烧伤后感染创面治疗的疗效分析[J].山西医药杂志,2020,49(20):2818-2819. [29]梁芳,高春锦,刘雪华,等．高压氧预处理对皮瓣移植术后大鼠缺血再灌注损伤炎症反应的影响[J].中华航海医学与高气压医学杂志,2015,19(3):176-179.

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更新日期/Last Update: 1900-01-01