[1]卓明词,周柳红,易保连.静脉输注瑞芬太尼对剖宫产术中卡前列素氨丁三醇不良反应的影响[J].医学信息,2021,34(06):160-162.[doi:10.3969/j.issn.1006-1959.2021.06.042]
　ZHUO Ming-ci,ZHOU Liu-hong,YI Bao-lian.Effect of Intravenous Infusion of Remifentanil on Adverse Reactions of Carboprost Tromethamine During Cesarean Section[J].Medical Information,2021,34(06):160-162.[doi:10.3969/j.issn.1006-1959.2021.06.042]
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静脉输注瑞芬太尼对剖宫产术中卡前列素氨丁三醇不良反应的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年06期
页码:
160-162
栏目:
药物与临床
出版日期:
2021-03-15

文章信息/Info

Title:
Effect of Intravenous Infusion of Remifentanil on Adverse Reactions of Carboprost Tromethamine During Cesarean Section
文章编号:
1006-1959（2021）06-0160-03
作者:
卓明词; 周柳红; 易保连
（1.雷州市人民医院麻醉科，广东 雷州 524200； 2.广东省农垦中心医院麻醉科，广东 湛江 524002）
Author(s):
ZHUO Ming-ci; ZHOU Liu-hong; YI Bao-lian
(1.Department of Anesthesiology,Leizhou People’s Hospital,Leizhou 524200,Guangdong,China； 2.Department of Anesthesiology, Guangdong Agricultural Reclamation Central Hospital,Zhanjiang,524002, Guangdong,China)
关键词:
瑞芬太尼; 卡前列素氨丁三醇; 子宫下段剖宫产术; 不良反应
Keywords:
Remifentanil; Carprost tromethamine; Lower uterine cesarean section; Adverse reactions
分类号:
R614.4；R719.8
DOI:
10.3969/j.issn.1006-1959.2021.06.042
文献标志码:
A
摘要:
目的 探讨静脉输注瑞芬太尼对剖宫产术中卡前列素氨丁三醇不良反应的影响。方法 选择2018年1月~2020年5月在我院择期行子宫下段剖宫产术患者60例，采用随机数字表法分为实验组和对照组，每组30例。两组均采用腰硬联合麻醉，在胎儿娩出后子宫体注射卡前列素氨丁三醇。实验组在胎儿娩出后立即静脉输注瑞芬太尼，对照组不给药。比较两组子宫体注射卡前列素氨丁三醇后恶心呕吐、胸闷、血压升高发生情况，两组入室（T0）、注射卡前列素氨丁三醇10 min后（T1）、术毕（T2）时平均动脉压、心率及需要静脉注射昂丹司琼、地佐辛补救情况。结果 实验组恶心呕吐、胸闷、血压升高发生率低于对照组（P＜0.05）；实验组T1时MAP、HR低于对照组（P＜0.05）；两组T0、T2时MAP、HR比较，差异均无统计学意义（P＞0.05）；实验组需要静脉注射昂丹司琼或地佐辛补救发生率低于对照组（P＜0.05）。结论 静脉输注瑞芬太尼能有效降低子宫下段剖宫产术中应用卡前列素氨丁三醇所致的不良反应，维持血流动力学稳定，减少补救性药物使用。
Abstract:
Objective To explore the effect of intravenous infusion of remifentanil on the adverse reactions of carboprost tromethamine during cesarean section.Methods From January 2018 to May 2020, 60 patients undergoing selective lower uterine cesarean section in our hospital were selected and divided into experimental group and control group by random number table method, with 30 cases in each group.Both groups underwent combined spinal-epidural anesthesia, and carboprost tromethamine was injected into the uterus after the fetus was delivered.The experimental group received intravenous infusion of remifentanil immediately after the fetus was delivered, and the control group did not receive it.To compare the occurrence of nausea and vomiting, chest tightness, and elevated blood pressure after carboprost tromethamine injection in the uterus of the two groups. The two groups were admitted to the room (T0), 10 min after carprost tromethamine injection (T1), and the operation was completed (T2) Hourly mean arterial pressure, heart rate, and need for intravenous ondansetron and dezocine remedial conditions.Results The incidence of nausea, vomiting, chest tightness, and elevated blood pressure in the experimental group was lower than that in the control group (P＜0.05);The MAP and HR of the experimental group at T1 were lower than those of the control group (P＜0.05);There was no statistically significant difference in MAP and HR between the two groups at T0 and T2 (P＞0.05);The incidence of salvage in the experimental group requiring intravenous injection of ondansetron or dezocine was lower than that of the control group (P＜0.05).Conclusion Intravenous infusion of remifentanil can effectively reduce the adverse reactions caused by carboprost tromethamine during lower uterine cesarean section, maintain hemodynamic stability, and reduce the use of salvage drugs.

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更新日期/Last Update: 1900-01-01