[1]李树贤,李 倩.宫腔镜手术麻醉中应用右美托咪定与瑞芬太尼复合依托咪酯的效果比较[J].医学信息,2022,35(11):114-117.[doi:10.3969/j.issn.1006-1959.2022.11.029]
　LI Shu-xian,LI Qian.Comparison of the Effect of Dexmedetomidine and Remifentanil Combined with Etomidate in Hysteroscopic Surgery Anesthesia[J].Medical Information,2022,35(11):114-117.[doi:10.3969/j.issn.1006-1959.2022.11.029]
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宫腔镜手术麻醉中应用右美托咪定与瑞芬太尼复合依托咪酯的效果比较()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年11期
页码:
114-117
栏目:
论著
出版日期:
2022-06-01

文章信息/Info

Title:
Comparison of the Effect of Dexmedetomidine and Remifentanil Combined with Etomidate in Hysteroscopic Surgery Anesthesia
文章编号:
1006-1959（2022）11-0114-04
作者:
李树贤; 李 倩
（天津市宝坻区中医医院麻醉科，天津 301800）
Author(s):
LI Shu-xian; LI Qian
(Department of Anesthesiology,Baodi District Hospital of Traditional Chinese Medicine,Tianjin 301800,China)
关键词:
宫腔镜手术; 麻醉; 右美托咪定; 瑞芬太尼; 依托咪酯; 血流动力学
Keywords:
Hysteroscopic surgery; Anesthesia; Dexmedetomidine; Remifentanil; Etomidate; Hemodynamics
分类号:
R614
DOI:
10.3969/j.issn.1006-1959.2022.11.029
文献标志码:
A
摘要:
目的 比较右美托咪定与瑞芬太尼复合依托咪酯在宫腔镜手术麻醉中的应用效果。方法 选择2019年10月-2021年5月天津市宝坻区中医医院收治的72例接受宫腔镜手术治疗的患者，根据住院号尾数的单双数分为右美托咪定组与瑞芬太尼组，每组36例。右美托咪定组给予右美托咪定复合依托咪酯麻醉，瑞芬太尼组给予瑞芬太尼复合依托咪酯麻醉，比较两组不同时间血流动力学、围术期麻醉指标、镇静镇痛效果及用药安全性。结果 两组T0、T1、T2、T3、T4动脉血氧分压（SpO2）比较，差异无统计学意义（P＞0.05）；右美托咪定组T1、T2、T3、T4时心率（HR）、平均动脉压（MAP）及脑电双频指数（BIS）均低于瑞芬太尼组，差异有统计学意义（P＜0.05）；右美托咪定组麻醉起效时间、麻醉苏醒时间、离室时间均短于瑞芬太尼组，差异有统计学意义（P＜0.05）；右美托咪定组A1、A3、A4时Ramsay镇静评分均低于瑞芬太尼组，差异有统计学意义（P＜0.05）；右美托咪定组B1、B2、B3、B4时VAS评分均低于瑞芬太尼组，差异有统计学意义（P＜0.05）；右美托咪定组麻醉不良反应发生率为11.11%，低于瑞芬太尼组的36.11%，差异有统计学意义（P＜0.05）。结论 右美托咪定与瑞芬太尼复合依托咪酯在宫腔镜手术中均有较理想的麻醉效果，但右美托咪定复合依托咪酯麻醉对血流动力学影响更小，镇静镇痛效果更明显，术后麻醉复苏效果更为理想，且用药安全性更高。
Abstract:
Objective To compare the application effect of dexmedetomidine and remifentanil combined with etomidate in hysteroscopic surgery anesthesia.Methods A total of 72 patients who underwent hysteroscopic surgery in Tianjin Baodi District Hospital of Traditional Chinese Medicine from October 2019 to May 2021 were selected and divided into dexmedetomidine group and remifentanil group according to the single and double number of hospitalization numbers, with 36 cases in each group. The dexmedetomidine group was given dexmedetomidine combined with etomidate anesthesia, and the remifentanil group was given remifentanil combined with etomidate anesthesia. The hemodynamics, perioperative anesthesia indexes, sedative and analgesic effects and medication safety of the two groups at different times were compared.Results There was no significant difference in arterial oxygen partial pressure (SpO2) at T0, T1, T2, T3 and T4 between the two groups (P>0.05). The heart rate (HR), mean arterial pressure (MAP) and bispectral index (BIS) at T1, T2, T3 and T4 in dexmedetomidine group were lower than those in remifentanil group, and the difference was statistically significant (P<0.05). The onset time of anesthesia, anesthesia recovery time and extubation time in dexmedetomidine group were shorter than those in remifentanil group, and the differences were statistically significant (P<0.05). Ramsay sedation scores at A1, A3 and A4 in dexmedetomidine group were lower than those in remifentanil group, and the difference was statistically significant (P<0.05). The VAS scores of dexmedetomidine group at B1, B2, B3 and B4 were lower than those of remifentanil group, and the difference was statistically significant (P<0.05). The incidence of adverse anesthesia reactions in dexmedetomidine group was 11.11%, which was lower than 36.11% in remifentanil group, and the difference was statistically significant (P<0.05).Conclusion Dexmedetomidine and remifentanil combined with etomidate have ideal anesthesia effect in hysteroscopic surgery. However, dexmedetomidine combined with etomidate anesthesia has less effect on hemodynamics, more obvious sedative and analgesic effect, more ideal postoperative anesthesia recovery effect, and higher medication safety.

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更新日期/Last Update: 1900-01-01