[1]王红娟,胡 雯,赵 娟,等.新疆地区单纯疱疹病毒Ⅱ型抗体检测结果分析[J].医学信息,2021,34(10):156-157.[doi:10.3969/j.issn.1006-1959.2021.10.045]
　WANG Hong-juan,HU Wen,ZHAO Juan,et al.Analysis of Detection Results of Herpes Simplex Virus-type Ⅱ Antibody in Xinjiang[J].Medical Information,2021,34(10):156-157.[doi:10.3969/j.issn.1006-1959.2021.10.045]
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新疆地区单纯疱疹病毒Ⅱ型抗体检测结果分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年10期
页码:
156-157
栏目:
调查分析
出版日期:
2021-05-15

文章信息/Info

Title:
Analysis of Detection Results of Herpes Simplex Virus-type Ⅱ Antibody in Xinjiang
文章编号:
1006-1959（2021）10-0156-02
作者:
王红娟; 胡 雯; 赵 娟; 等
（新疆维吾尔自治区人民医院皮肤性病科/新疆皮肤病研究重点实验室，新疆 乌鲁木齐 830001）
Author(s):
WANG Hong-juan; HU Wen; ZHAO Juan; et al.
(Department of Dermatology and Venereology,People’s Hospital of Xinjiang Uygur Autonomous Region/Key Laboratory of Dermatology Research in Xinjiang,Urumqi 830001,Xinjiang,China)
关键词:
生殖器疱疹; 单纯疱疹Ⅱ型; 酶联免疫吸附法
Keywords:
Genital herpes; Herpes simplex virus-type Ⅱ; Enzyme linked immunosorbent assay
分类号:
R752.1+1
DOI:
10.3969/j.issn.1006-1959.2021.10.045
文献标志码:
A
摘要:
目的 了解本地区疑似生殖器疱疹（GH）患者单纯疱疹病毒Ⅱ型抗体感染情况（HSV-Ⅱ）。方法 选取2018年5月~2019年7月在我院皮肤性病科门诊就诊，疑似GH的患者1036例，用酶联免疫吸附法（ELISA）检测疑似生殖器疱疹不同性别、不同年龄段患者血清中的HSV-Ⅱ IgG及IgM抗体。结果 1036例疑似GH患者中 HSV-Ⅱ抗体总阳性率33.11%,其中IgG抗体的阳性率高于IgM抗体的阳性率，差异有统计学意义（P＜0.05）；男性患者HSV-Ⅱ抗体阳性率29.52%，低于女性患者的37.04%，差异有统计学意义（P＜0.05）；不同性别患者HSV-ⅡIgG抗体阳性率均高于IgM抗体阳性率，差异有统计学意义（P＜0.05）。＜20岁、20~40岁、41~60岁、＞60岁各年龄段HSV-Ⅱ抗体阳性率依次为9.26%,35.93%,36.61%,26.94%，不同年龄段HSV-Ⅱ抗体阳性率比较，差异有统计学意义（P＜0.05）。结论 本地区HSV-Ⅱ总体感染率较高，主要以HSV-ⅡIgG抗体感染为主，有性别差异，有呈向高龄化发展的趋势，加强高危人群HSV-Ⅱ抗体的检测对生殖器疱疹的防控和诊断具有重要的临床意义。
Abstract:
Objective To understand the infection status of herpes simplex virus-type Ⅱ antibody (HSV-Ⅱ) in patients with suspected genital herpes (GH) in this area.Methods A total of 1,036 patients with suspected GH were selected from May 2018 to July 2019 in the outpatient department of the Department of Dermatology and Venereology of our hospital.Enzyme-linked immunosorbent assay (ELISA) was used to detect HSV-Ⅱ IgG and IgM antibodies in the serum of suspected genital herpes patients of different genders and different ages.Results The total positive rate of HSV-Ⅱ antibody in 1036 suspected GH patients was 33.11%. The positive rate of IgG antibody was higher than that of IgM antibody,the difference was statistically significant (P＜0.05);The positive rate of HSV-Ⅱ antibody in male patients was 29.52%, which was lower than 37.04% in female patients,the difference was statistically significant (P＜0.05);The positive rate of HSV-ⅡIgG antibody in patients of different genders was higher than that of IgM antibody,the difference was statistically significant (P＜0.05).The positive rate of HSV-Ⅱ antibody in each age group of ＜20 years old, 20~40 years old, 41~60 years old,> 60 years old was 9.26%, 35.93%, 36.61%, and 26.94%. Comparison of HSV-Ⅱ antibody positive rates in different age groups,the difference was statistically significant (P＜0.05).Conclusion The overall HSV-Ⅱ infection rate in this area is relatively high, mainly HSV-ⅡIgG antibody infection, with gender differences, and a trend toward aging. Strengthen the detection of HSV-Ⅱ antibodies in high-risk populations to prevent and control genital herpes And diagnosis has important clinical significance.

参考文献/References:

[1]Groves MJ.Genital Herpes:A Review[J].American Family Physician,2016,93(11):928-934.[2]Nardone R,Versace V,Brigo F,et al.Herpes Simplex Virus Type 2 Myelitis: Case Report and Review of the Literature[J].Frontiers in Neurology,2017(8):199.[3]Arun V,Michael BD,Probasco JC,et al.Acute encephalitis in immunocompetent adults[J].Acute Encephalitis in Immunocompetent Adults,2019,393(10172):702-716.[4]谢春,朱海东,马红英,等.感染2型单纯疱疹病毒对人宫颈上皮细胞自噬活性及 IFN-β、IL-6 表达的影响[J].山东医药,2018,58(4):45-47. [5]王耀斐,朱参胜,贺琪,等.2013-2016年性病门诊单纯疱疹病毒血清学检测结果分析[J].陕西医学杂志,2018,47(3):398-400.[6]朱劲涛,高东花,欧阳红艳,等.性病患者血清HSV-2抗体检测研究[J].中国现代药物应用,2019,13(12):75-76.[7]杨勇,孙伟,吴保华.475例单纯疱疹病毒2型基因检测结果分析[J].中国医药科学,2014(14):34-36.

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更新日期/Last Update: 1900-01-01