[1]冯宏达.磷酸奥司他韦联合蓝芩口服液治疗儿童流感的疗效[J].医学信息,2021,34(11):161-163.[doi:10.3969/j.issn.1006-1959.2021.11.045]
　FENG Hong-da.Efficacy of Oseltamivirphosphate Combined with LanQinKouFuYe in Treating Children’s Influenza[J].Medical Information,2021,34(11):161-163.[doi:10.3969/j.issn.1006-1959.2021.11.045]
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磷酸奥司他韦联合蓝芩口服液治疗儿童流感的疗效()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年11期
页码:
161-163
栏目:
药物与临床
出版日期:
2021-06-01

文章信息/Info

Title:
Efficacy of Oseltamivirphosphate Combined with LanQinKouFuYe in Treating Children’s Influenza
文章编号:
1006-1959（2021）11-0161-03
作者:
冯宏达
（佳木斯市中心医院儿内科，黑龙江 佳木斯 154007）
Author(s):
FENG Hong-da
(Department of Pediatrics,Jiamusi Central Hospital,Jiamusi 154007,Heilongjiang,China)
关键词:
磷酸奥司他韦; 蓝芩口服液; 儿童流感
Keywords:
Oseltamivirphosphate; LanQinKouFuYe; Children influenza
分类号:
R725
DOI:
10.3969/j.issn.1006-1959.2021.11.045
文献标志码:
A
摘要:
目的 观察磷酸奥司他韦联合蓝芩口服液治疗儿童流感的疗效。方法 选取2019年10月~2020年10月我院诊治的74例儿童流感患儿为研究对象，采用随机数字表法分为对照组和观察组，各37例。对照组采用磷酸奥司他韦治疗，观察组在对照组基础上联合蓝芩口服液治疗，比较两组临床治疗疗效、临床症状消退时间、临床症状评分、免疫功能指标以及临床不良反应发生情况。结果 观察组治疗总有效率为97.29%，高于对照组的83.78%，差异有统计学意义（P＜0.05）；观察组临床发热、咳嗽、流鼻涕、鼻塞症状消退时间均短于对照组，差异有统计学意义（P＜0.05）；观察组发热、鼻塞、咳嗽、流鼻涕症状评分均低于对照组，差异有统计学意义（P＜0.05）；观察组血清IgA、IgG、IgM水平均高于对照组，差异有统计学意义（P＜0.05）；观察组治疗不良反应发生率为8.11%，与对照组的5.41%比较，差异无统计学意义（P＞0.05）。结论 磷酸奥司他韦联合蓝芩口服液治疗儿童流感效果理想，可提高治疗总有效率，减轻患儿临床症状，缩短症状消退时间，提高自身免疫力，且临床不良反应少。
Abstract:
Objective To observe the efficacy of Oseltamivirphosphate combined with LanQinKouFuYe in the treatment of children with influenza.Methods A total of 74 children with influenza who were diagnosed and treated in our hospital from October 2019 to October 2020 were selected as the research objects. They were divided into control group and observation group by random number table method, with 37 cases in each group.The control group was treated with Oseltamivirphosphate, and the observation group was treated with LanQinKouFuYe on the basis of the control group. The two groups were compared with clinical treatment efficacy, clinical symptom resolution time, clinical symptom score, immune function index and clinical adverse reactions.Results The total effective rate of treatment in the observation group was 97.29%, which was higher than 83.78% in the control group,the difference was statistically significant (P<0.05);The time for clinical fever, cough, runny nose, and nasal congestion in the observation group to resolve was shorter than that in the control group,the difference was statistically significant (P<0.05);The scores of fever, nasal congestion, cough, and runny nose in the observation group were lower than those in the control group,the difference was statistically significant (P<0.05);The levels of serum IgA, IgG, and IgM in the observation group were higher than those in the control group,the difference was statistically significant(P<0.05);The incidence of adverse reactions in the observation group was 8.11%, and that in the control group was 5.41%,the difference was not statistically significant (P>0.05).Conclusion Oseltamivirphosphate combined with LanQinKouFuYe has an ideal effect in the treatment of children with influenza. It can improve the total effective rate of treatment, reduce the clinical symptoms of children, shorten the time of symptom resolution, improve autoimmunity, and have fewer clinical adverse reactions.

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更新日期/Last Update: 1900-01-01