[1]翟浩宇,扎西多吉.内镜下止血联合生长抑素治疗消化性溃疡出血的疗效及其对胃肠功能的影响[J].医学信息,2021,34(14):127-129.[doi:10.3969/j.issn.1006-1959.2021.14.034]
　ZHAI Hao-yu,ZHAXI Duo-ji.Efficacy of Endoscopic Hemostasis Combined with Somatostatin in the Treatment of Peptic Ulcer Bleeding and Its Influence on Gastrointestinal Function[J].Medical Information,2021,34(14):127-129.[doi:10.3969/j.issn.1006-1959.2021.14.034]
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内镜下止血联合生长抑素治疗消化性溃疡出血的疗效及其对胃肠功能的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年14期
页码:
127-129
栏目:
临床研究
出版日期:
2021-07-15

文章信息/Info

Title:
Efficacy of Endoscopic Hemostasis Combined with Somatostatin in the Treatment of Peptic Ulcer Bleeding and Its Influence on Gastrointestinal Function
文章编号:
1006-1959（2021）14-0127-03
作者:
翟浩宇; 扎西多吉
（1.天津医科大学第二医院消化内科，天津 300211； 2.西藏昌都市藏医院胃肠科，西藏 昌都 854000）
Author(s):
ZHAI Hao-yu; ZHAXI Duo-ji
(1.Department of Gastroenterology,Second Hospital of Tianjin Medical University,Tianjin 300211,China; 2.Department of Gastroenterology,Tibet Changdu Tibetan Hospital,Changdu 854000,Tibet,China)
关键词:
内镜止血; 生长抑素; 消化性溃疡出血; 胃肠功能
Keywords:
Endoscopic hemostasis; Somatostatin; Peptic ulcer bleeding; Gastrointestinal function
分类号:
R573.1
DOI:
10.3969/j.issn.1006-1959.2021.14.034
文献标志码:
A
摘要:
目的 研究内镜下止血联合生长抑素治疗消化性溃疡出血的疗效及其对胃肠功能的影响。方法 选取2019年6月~2020年6月我院接诊的96例消化性溃疡出血患者为研究对象，采用随机数字表法分为对照组和观察组，各48例。对照组采用生长抑素治疗，观察组在对照组基础上联合内镜止血，比较两组临床治疗总有效率、止血时间、输血量、空腹胃液pH、胃肠功能障碍评分、再出血发生率以及并发症发生率。结果 观察组治疗总有效率为95.83%，高于对照组的83.33%，差异有统计学意义（P＜0.05）；观察组空腹胃液pH值高于对照组，胃肠功能障碍评分低于对照组，差异有统计学意义（P＜0.05）；观察组平均止血时间、输血量均小于对照组，差异有统计学意义（P＜0.05）；观察组再出血发生率为4.16%，低于对照组的12.50%，差异有统计学意义（P＜0.05）；观察组并发症发生率为6.25%，与对照组的8.33%比较，差异无统计学意义（P＞0.05）。结论 内镜下止血联合生长抑素治疗消化性溃疡出血疗效确切，可缩短止血时间，减少输血量，降低空腹胃液pH值，有效改善患者胃肠功能，降低再出血发生率，且不会增加并发症发生几率。
Abstract:
Objective To study the efficacy of endoscopic hemostasis combined with somatostatin in the treatment of peptic ulcer bleeding and its influence on gastrointestinal function.Methods A total of 96 patients with peptic ulcer hemorrhage admitted to our hospital from June 2019 to June 2020 were selected as the research objects. They were divided into the control group and the observation group by random number table, with 48 cases in each group.The control group was treated with somatostatin,the observation group was combined with endoscopic hemostasis on the basis of the control group,the total effective rate of clinical treatment, hemostasis time, blood transfusion, fasting gastric juice pH, gastrointestinal dysfunction score, incidence of rebleeding, and incidence of complications were compared between the two groups.Results The total effective rate of treatment in the observation group was 95.83%, which was higher than 83.33% in the control group,the difference was statistically significant (P<0.05);The pH value of fasting gastric juice in the observation group was higher than that of the control group, and the gastrointestinal dysfunction score was lower than that of the control group, the difference was statistically significant (P<0.05);The average hemostasis time and blood transfusion volume of the observation group were less than those of the control group,the difference was statistically significant (P<0.05);The incidence of rebleeding in the observation group was 4.16%, which was lower than 12.50% in the control group,the difference was statistically significant (P<0.05);The complication rate in the observation group was 6.25%, which was not statistically significant compared with 8.33% in the control group (P>0.05).Conclusion Endoscopic hemostasis combined with somatostatin is effective in treating peptic ulcer bleeding.It can shorten the time of hemostasis, reduce the amount of blood transfusion, reduce the pH value of fasting gastric juice, effectively improve the patient’s gastrointestinal function, reduce the incidence of rebleeding, and will not increase the probability of complications.

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更新日期/Last Update: 1900-01-01