[1]李京洲.巴曲酶联合单次蛛网膜下腔麻醉在血小板减少产妇中的应用效果[J].医学信息,2021,34(16):163-165,168.[doi:10.3969/j.issn.1006-1959.2021.16.046]
　LI Jing-zhou.The Effect of Batroxobin Combined with A Single Subarachnoid Anesthesia in Thrombocytopenic Parturients[J].Medical Information,2021,34(16):163-165,168.[doi:10.3969/j.issn.1006-1959.2021.16.046]
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巴曲酶联合单次蛛网膜下腔麻醉在血小板减少产妇中的应用效果()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年16期
页码:
163-165,168
栏目:
药物与临床
出版日期:
2021-08-15

文章信息/Info

Title:
The Effect of Batroxobin Combined with A Single Subarachnoid Anesthesia in Thrombocytopenic Parturients
文章编号:
1006-1959（2021）16-0163-04
作者:
李京洲
（佳木斯市中心医院麻醉科，黑龙江 佳木斯 154002）
Author(s):
LI Jing-zhou
(Department of Anesthesiology,the Central Hospital of Jiamusi City,Jiamusi 154002,Heilongjiang,China)
关键词:
巴曲酶; 单次蛛网膜下腔麻醉; 剖宫产; Apgar评分; 血流动力学
Keywords:
Batroxobin; Single subarachnoid anesthesia; Cesarean section; Apgar score; Hemodynamic
分类号:
R614
DOI:
10.3969/j.issn.1006-1959.2021.16.046
文献标志码:
A
摘要:
目的 探讨巴曲酶联合单次蛛网膜下腔麻醉在血小板减少产妇中应用效果。方法 选取2018年6月~2020年6月我院收治的80例血小板减少产妇作为研究对象，应用随机数字表法将患者分为观察组与对照组，每组40例。对照组使用单次蛛网膜下腔麻醉，观察组在对照组基础上联合使用巴曲酶，比较两组产妇麻醉前（T0）、麻醉后（T1）、胎儿娩出时（T2）的血流动力学变化，手术指标及血小板变化指标、新生儿Apgar评分以及术后不良反应情况。结果 T0时点，两组产妇SVV、SVI、CI、MAP、HR比较，差异无统计学意义（P＞0.05）；T1时点，观察组SVI、MAP高于对照组，差异有统计学意义（P＜0.05），而两组SVV、CI、HR比较，差异无统计学意义（P＞0.05）；T2时点，观察组HR高于对照组，差异有统计学意义（P＜0.05），而两组SVV、SVI、CI、MAP比较，差异无统计学意义（P＞0.05）。两组手术时间比较，差异无统计学意义（P＞0.05），观察组术后血小板计数高于对照组，术中出血量低于对照组，差异有统计学意义（P＜0.05）。观察组新生儿出生后1、5、10 min Apgar评分高于对照组，差异有统计学意义（P＜0.05）。研究组不良反应总发生率低于对照组，差异有统计学意义（P＜0.05）。结论 巴曲酶联合单次蛛网膜下腔麻醉能够减少产妇血流动力学指标变化，增加术后血小板计数，减少产妇术中出血量，提高新生儿Apgar评分，应用安全有效。
Abstract:
Objective To investigate the effect of batroxobin combined with a single subarachnoid anesthesia in the thrombocytopenic parturients.Methods 80 cases of thrombocytopenic parturients admitted to our hospital from June 2018 to June 2020 were selected as the research objects.The patients were divided into observation group and control group by random number table method, with 40 cases in each group.The control group was given a single subarachnoid anesthesia, and the observation group was combined with Batroxobin on the basis of the control group.The hemodynamic changes before anesthesia (T0), after anesthesia (T1), and fetus delivery (T2), changes in surgical and platelet indexes, Apgar scores of newborns, and postoperative adverse reactions were compared between the two groups.Results At T0, there was no significant difference in SVV, SVI, CI, MAP, HR between the two groups of parturients (P>0.05);At T1, the SVI and MAP of the observation group were higher than those of the control group,the difference was statistically significant(P＜0.05).There was no statistically significant difference in SVV, CI, HR between the two groups (P>0.05);At T2, the HR of the observation group was higher than that of the control group,the difference was statistically significant(P＜0.05).There was no statistically significant difference between the two groups of SVV, SVI, CI, MAP (P>0.05).There was no statistically significant difference in operation time between the two groups (P>0.05).The postoperative platelet count of the study group was higher than that of the control group, and the intraoperative blood loss was lower than that of the control group,the difference was statistically significant(P<0.05).The Apgar scores of newborns in the study group were higher than those in the control group at 1, 5, and 10 min after birth,the difference was statistically significant(P<0.05).The total incidence of adverse reactions in the study group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion Batroxobin combined with a single subarachnoid anesthesia can reduce maternal hemodynamic changes, increase postoperative platelet count, reduce maternal blood loss during surgery, and increase neonatal Apgar score. The application is safe and effective.

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更新日期/Last Update: 1900-01-01