[1]殷海珍.南京地区小儿呼吸道感染的病原体检测结果分析[J].医学信息,2021,34(21):141-143.[doi:10.3969/j.issn.1006-1959.2021.21.039]
　YIN Hai-zhen.Analysis of Pathogen Detection Results of Respiratory Tract Infection in Children in Nanjing[J].Medical Information,2021,34(21):141-143.[doi:10.3969/j.issn.1006-1959.2021.21.039]
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南京地区小儿呼吸道感染的病原体检测结果分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年21期
页码:
141-143
栏目:
调查分析
出版日期:
2021-11-01

文章信息/Info

Title:
Analysis of Pathogen Detection Results of Respiratory Tract Infection in Children in Nanjing
文章编号:
1006-1959（2021）21-0141-03
作者:
殷海珍
（南京医科大学第四附属医院儿科，江苏 南京 210000）
Author(s):
YIN Hai-zhen
(Department of Pediatrics,the Fourth Affiliated Hospital of Nanjing Medical University,Nanjing 210000,Jiangsu,China)
关键词:
呼吸道病原体; 甲型流感病毒; 肺炎链球菌
Keywords:
Respiratory pathogens; Influenza A virus; Streptococcus pneumoniae
分类号:
R725.6
DOI:
10.3969/j.issn.1006-1959.2021.21.039
文献标志码:
A
摘要:
目的 分析南京地区小儿呼吸道感染的病原体检测结果。方法 选取我院2019年11月-2020年10月共937例呼吸道疾病住院患儿作为研究对象，所有患儿均接受呼吸道病原体核酸检测，分析上呼吸道及下呼吸道疾病病原体核酸检测结果，并对不同性别、年龄患儿阳性率进行比较。结果 上呼吸道疾病共121例，检测阳性102例，阳性率为84.30%；上呼吸道疾病病原体核酸检测阳性率最高的病原体为甲型流感病毒，其次分别为呼吸道合胞病毒、肺炎支原体、乙型流感病毒、副流感病毒、腺病毒以及肺炎衣原体。下呼吸道疾病共816例，检测阳性728例，阳性率为89.22%；下呼吸道疾病病原体核酸检测阳性率最高的病原体为肺炎链球菌，其次分别为呼吸道合胞病毒、流感嗜血杆菌、肺炎克雷伯菌、肺炎支原体、副流感病毒、卡他莫拉菌、百日咳杆菌、肺炎衣原体、鼻病毒以及人博卡病毒。不同性别患儿阳性率比较，差异无统计学意义（P>0.05）。1岁以下患儿阳性率高于1~5岁、6~10岁患儿，差异有统计学意义（P＜0.05）；而1~5岁和6~10岁患儿阳性率比较，差异无统计学意义（P＞0.05）。结论 小儿上呼吸道疾病病原体中甲型流感病毒检测阳性率最高，下呼吸道疾病病原体中肺炎链球菌检测阳性率最高，且1岁以下患儿最容易受到呼吸道病原体的侵袭，临床中通过呼吸道病原体核酸检测的方式，能够明确患儿的病原体，为临床治疗提供参考。
Abstract:
Objective To analyze the pathogen detection results of respiratory tract infection in children in Nanjing.Methods A total of 937 hospitalized children with respiratory diseases in our hospital from November 2019 to October 2020 were selected as subjects. All children received nucleic acid detection of respiratory pathogens. The nucleic acid detection results of upper respiratory tract and lower respiratory tract diseases were analyzed, and the positive rates of children with different genders and ages were compared.Results Of 121 cases of upper respiratory diseases, 102 were positive, the positive rate was 84.30%. Influenza A virus had the highest positive rate of nucleic acid detection for pathogens of upper respiratory diseases, followed by respiratory syncytial virus, mycoplasma pneumoniae, influenza B virus, parainfluenza virus, adenovirus and chlamydia pneumoniae. Of 816 cases of lower respiratory tract diseases, 728 were positive, the positive rate of 89.22%. Streptococcus pneumoniae had the highest positive rate of nucleic acid detection for pathogens of lower respiratory tract diseases, followed by respiratory syncytial virus, Haemophilus influenzae, Klebsiella pneumoniae, Mycoplasma pneumoniae, parainfluenza virus, Moraxella catarrhiae, Bacillus perpersis, Chlamydia pneumoniae, rhinovirus and human boca virus. There was no significant difference in the positive rate of children with different genders (P>0.05). The positive rate of children under 1 year old was higher than that of children aged 1-5 years old and 6-10 years old, and the difference was statistically significant (P<0.05); while there was no significant difference in the positive rate between 1–5 years old and 6–10 years old children (P>0.05).Conclusion The positive rate of influenza A virus is the highest in the pathogens of upper respiratory tract diseases in children, and the positive rate of Streptococcus pneumoniae is the highest in the pathogens of lower respiratory tract diseases. Children under 1 year old are most vulnerable to the invasion of respiratory pathogens. In clinical practice, nucleic acid detection of respiratory pathogens can identify the pathogens of children and provide reference for clinical treatment.

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更新日期/Last Update: 1900-01-01