[1]万久琴,戴 澄.2020年江都区疑似预防接种异常反应发生情况分析[J].医学信息,2021,34(21):144-146.[doi:10.3969/j.issn.1006-1959.2021.21.040]
　WAN Jiu-qin,DAI Cheng.Analysis on Incidence of Suspected Immunization Abnormal Reaction in Jiangdu District in 2020[J].Medical Information,2021,34(21):144-146.[doi:10.3969/j.issn.1006-1959.2021.21.040]
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2020年江都区疑似预防接种异常反应发生情况分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年21期
页码:
144-146
栏目:
调查分析
出版日期:
2021-11-01

文章信息/Info

Title:
Analysis on Incidence of Suspected Immunization Abnormal Reaction in Jiangdu District in 2020
文章编号:
1006-1959（2021）21-0144-03
作者:
万久琴; 戴 澄
（扬州市江都区疾病预防控制中心传染病防治与免疫规划科，江苏 扬州 225200）
Author(s):
WAN Jiu-qin; DAI Cheng
(Department of Infectious Disease Control and Immunization Planning,Jiangdu District Center for Disease Control and Prevention,Yangzhou 225200,Jiangsu,China)
关键词:
预防接种; 异常反应; 疫苗; 发热; 皮疹
Keywords:
Vaccination; Abnormal reaction; Vaccine; Fever; Skin rash
分类号:
R186
DOI:
10.3969/j.issn.1006-1959.2021.21.040
文献标志码:
A
摘要:
目的 分析江都区2020年疑似预防接种异常反应发生情况。方法 收集2020年1月-12月江都区167例疑似预防接种异常反应者临床资料，其中138例一般反应，29例异常反应，观察预防接种异常反应发生情况，分析预防接种异常反应者流行病学分布特点、异常反应发生时间间隔、临床异常反应诊断分布特点、不同疫苗异常反应发生情况。结果 疑似预防接种异常反应中男性发生率高于女性，且男女性别比为1.25∶1，一般反应中1~6岁比例（58.69%）最高，异常反应中＜1岁比例（51.72%）最高，第一季度发生率均低于其他三个季度；疑似预防接种异常反应主要发生在接种后＜1 d，占58.08%，临床一般反应主要以发热、局部红肿、硬结为主，占72.16%，异常反应以过敏性皮疹和荨麻疹为主，分别占68.96%和20.68%；吸附无细胞百白破灭活脊髓灰质和b型流感嗜血杆菌联合疫苗疑似预防接种异常反应发生率最高，麻疹风疹联合减毒活疫苗、13价肺炎球菌多糖结合疫苗次之，其中一般反应以吸附无细胞百白破灭活脊髓灰质和b型流感嗜血杆菌联合疫苗最高，异常反应以麻疹风疹联合减毒活疫苗发生最高。结论 江都区疑似预防接种异常反应男性发生率较高，多发生于＜1岁接种者，且多数发生于接种后1 d，以一般异常反应为主，异常反应率较低，且异常反应均在正常范围内。
Abstract:
Objective To analyze the occurrence of suspected immunization abnormal reaction in Jiangdu District district in 2020.Methods Clinical data of 167 cases of suspected abnormal reaction to immunization in Jiangdu District from January 2020 to December 2020 were collected, including 138 cases of general reaction and 29 cases of abnormal reaction. The occurrence of abnormal reaction to immunization was observed, and the epidemiological distribution characteristics, time interval of abnormal reaction, diagnostic distribution characteristics of clinical abnormal reaction and occurrence of abnormal reaction to different vaccines were analyzed.Results The incidence of male was higher than that of female in the abnormal reaction of suspected vaccination, and the gender ratio was 1.25:1. The proportion of 1-6 years old (58.69%) was the highest in the general reaction, and the proportion of <1 years old (51.72%) was the highest in the abnormal reaction. The incidence in the first quarter was lower than that in the other three quarters. The abnormal reactions of suspected vaccination mainly occurred <1 d after vaccination, accounting for 58.08%. The clinical general reactions were mainly fever, local redness and swelling, and sclerosis, accounting for 72.16%. The abnormal reactions were mainly allergic rash and urticaria, accounting for 68.96% and 20.68%, respectively. The incidence of abnormal vaccination reaction was the highest in the combined vaccine of cell-free pertussis inactivated spinal cord gray matter and Haemophilus influenzae type b, followed by measles rubella combined attenuated live vaccine and 13-valent pneumococcal polysaccharide combined vaccine. The general reaction was the highest in the combined vaccine of cell-free pertussis inactivated spinal cord gray matter and Haemophilus influenzae type b, and the abnormal reaction was the highest in measles rubella combined attenuated live vaccine.Conclusion The incidence of suspected vaccination abnormal reaction in males in Jiangdu District is higher, which mostly occurs in people under 1 year old, and most of them occur at 1 day after inoculation. The general abnormal reaction is the main, and the abnormal reaction rate is low, and the abnormal reactions are within the normal range.

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更新日期/Last Update: 1900-01-01