[1]孔丹青,邱 波,曾 灵,等.磁共振扩散峰度成像在乳腺良恶性病变鉴别诊断中的价值[J].医学信息,2022,35(02):175-177.[doi:10.3969/j.issn.1006-1959.2022.02.046]
　KONG Dan-qing,QIU Bo,ZENG Ling,et al.The Value of Diffusion Kurtosis Imaging in the Differential Diagnosis of Benign andMalignant Breast Lesions[J].Medical Information,2022,35(02):175-177.[doi:10.3969/j.issn.1006-1959.2022.02.046]
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磁共振扩散峰度成像在乳腺良恶性病变鉴别诊断中的价值()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年02期
页码:
175-177
栏目:
诊疗技术
出版日期:
2022-01-15

文章信息/Info

Title:
The Value of Diffusion Kurtosis Imaging in the Differential Diagnosis of Benign andMalignant Breast Lesions
文章编号:
1006-1959（2022）02-0175-03
作者:
孔丹青; 邱 波; 曾 灵; 陈翠美; 唐湘雍; 王新正
深圳市龙华区人民医院医学影像科，广东 深圳 518109
Author(s):
KONG Dan-qing; QIU Bo; ZENG Ling; CHEN Cui-mei; TANG Xiang-yong; WANG Xin-zheng
Department of Medical Imaging,Shenzhen Longhua District People’s Hospital,Shenzhen 518109,Guangdong,China
关键词:
磁共振成像; 扩散峰度成像; 乳腺良恶性病变
Keywords:
Magnetic resonance imaging; Diffusion kurtosis imaging; Breast benign and malignant diseases
分类号:
R737.9
DOI:
10.3969/j.issn.1006-1959.2022.02.046
文献标志码:
A
摘要:
目的 研究磁共振扩散峰度成像（DKI）在乳腺良恶性病变鉴别诊断中的价值。方法 选取2020年4月-2021年4月我院诊治的43例乳腺病变患者，均进行双侧乳腺的常规磁共振成像（MRI）检查和DKI检查，分析平均扩散峰度（MK）、径向峰度（RK）、轴向峰度（AK）、平均扩散率（MD）、各向异性分数（FA）和径向扩散率（RD）参数值对乳腺良恶性疾病的诊断效能。结果 经手术病理证实共48个病灶，其中良性26个，恶性22个。恶性病灶MK、AK、RK、FA值均高于良性病灶，MD值低于良性病灶，差异有统计学意义（P＜0.05）；恶性病灶与良性病灶RD值比较，差异无统计学意义（P＞0.05）。ROC曲线分析显示，MK、AK、RK、FA、MD值敏感度分别为95.60%、86.43%、90.92%、82.93%、89.40%，特异度分别为88.58%、89.67%、66.78%、64.59%、87.45%，其中MK值敏感度高于AK、RK、FA、MD值，AK值特异度高于MK、RK、FA、MD值。结论 DKI在乳腺良恶性病变鉴别诊断中具有重要的价值，且MK、AK、MD参数值具有较高的敏感度、特异度，可作为乳腺良恶性病变鉴别诊断的重要参考指标。
Abstract:
Objective To investigate the value of diffusion kurtosis imaging (DKI) in the differential diagnosis of benign and malignant breast lesions.Methods A total of 43 patients with breast lesions diagnosed and treated in our hospital from April 2020 to April 2021 were selected for routine magnetic resonance imaging (MRI) and DKI scanning of bilateral breasts. The diagnostic efficacy of mean diffusion kurtosis (MK), radial kurtosis (RK), axial kurtosis (AK), mean diffusion rate (MD), anisotropic fraction (FA) and radial diffusion rate (RD) parameters on benign and malignant breast diseases was analyzed.Results A total of 48 lesions were confirmed by operation and pathology, including 26 benign and 22 malignant. The MK, AK, RK and FA values of malignant lesions were higher than those of benign lesions, and the MD value was lower than that of benign lesions, the difference was statistically significant (P<0.05). There was no significant difference in RD value between malignant lesions and benign lesions (P>0.05). ROC curve analysis showed that the sensitivity of MK, AK, RK, FA and MD was 95.60%, 86.43%, 90.92%, 82.93% and 89.40%, respectively, and the specificity was 88.58%, 89.67%, 66.78%, 64.59% and 87.45%, respectively. The sensitivity of MK was higher than that of AK, RK, FA and MD, and the specificity of AK was higher than that of MK, RK, FA and MD.Conclusion DKI has important value in the differential diagnosis of benign and malignant breast lesions, and MK, AK and MD parameters have high sensitivity and specificity, which can be used as an important reference index for the differential diagnosis of benign and malignant breast lesions.

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更新日期/Last Update: 1900-01-01