[1]潘 玲,刘玲玲,苏卫东.常规凝血功能指标与血栓弹力图在患者凝血功能检测中的对比研究[J].医学信息,2022,35(17):141-143.[doi:10.3969/j.issn.1006-1959.2022.17.039]
　PAN Ling,LIU Ling-ling,SU Wei-dong.Comparison of Thromboelastography and Conventional Coagulation in the Detection of Coagulation Function in Patients[J].Journal of Medical Information,2022,35(17):141-143.[doi:10.3969/j.issn.1006-1959.2022.17.039]
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常规凝血功能指标与血栓弹力图在患者凝血功能检测中的对比研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年17期
页码:
141-143
栏目:
诊疗技术
出版日期:
2022-09-01

文章信息/Info

Title:
Comparison of Thromboelastography and Conventional Coagulation in the Detection of Coagulation Function in Patients
文章编号:
1006-1959（2022）17-0141-03
作者:
潘 玲; 刘玲玲; 苏卫东
（天津第四中心医院检验科，天津 300142）
Author(s):
PAN Ling; LIU Ling-ling; SU Wei-dong
(Department of Clinical Laboratory,Tianjin Fourth Central Hospital,Tianjin 300142,China)
关键词:
血栓弹力图; 常规凝血三项; 凝血功能
Keywords:
Thromboelastogram; Three tests of routine coagulation; Coagulation function
分类号:
R446.11
DOI:
10.3969/j.issn.1006-1959.2022.17.039
文献标志码:
A
摘要:
目的 分析血栓弹力图（TEG）和常规凝血三项[凝血酶原时间（APTT）、凝血酶原时间（PT）、纤维蛋白原（FBG）]在患者凝血功能检测中的价值。方法 选取2020年5月-2021年5月在我院在进行凝血功能检测的70例患者为研究对象，分别进行血栓弹力和常规凝血三项检测，观察血栓弹力图检测指标[凝血活酶生成时间（R）、血凝块形成时间（K）、最大振幅（MA）、α角度（Angle）、常规凝血三项指标（APTT、PT、FBG）、TEG 与常规凝血三项试验的相关性、出血和血栓患者TEG与常规凝血三项检测灵敏度。结果 TEG的R值与PT、APTT均有直线相关性，TEG的K值、Angle、MA与FBG均有直线相关性（P＜0.05）；出血患者TEG的R值检测灵敏度高于PT、APTT，K值、Angle、MA检测的灵敏度均高于FBG（P＜0.05）；血栓患者TEG的R值检测灵敏度高于PT、APTT，Angle的检测灵敏度高于FBG，而K值和MA的检测灵敏度均低于FBG。结论 血栓弹力图和常规凝血三项在患者凝血功能检测中具有一定相关性，但是两种方法检测血栓和出血检测灵敏度均较低，一致性相对较弱。但是相对而言血栓弹力图灵敏度优于常规凝血三项检测，可更好的反应患者凝血过程。
Abstract:
Objective To analyze the value of thrombelastogram (TEG) and conventional coagulation parameters [prothrombin time (APTT), prothrombin time (PT), fibrinogen (FBG)] in the detection of coagulation function in patients.Methods A total of 70 patients who underwent coagulation function testing in our hospital from May 2020 to May 2021 were selected as the research objects, and three tests of thrombelelastic and conventional coagulation were performed, respectively. Thrombelastogram detection indexes [thrombin generation time (R), blood clot formation time (K), maximum amplitude (MA), α angle (Angle), conventional coagulation three indexes (APTT, PT, FBG), correlation between TEG and conventional coagulation three tests, and sensitivity of TEG and conventional coagulation three tests in patients with hemorrhage and thrombosis were observed.Results R value of TEG had linear correlation with PT and APTT, K value, Angle and MA of TEG had linear correlation with FBG (P<0.05). The sensitivity of R value of TEG in patients with hemorrhage was higher than that of PT and APTT, and the sensitivity of K value, Angle and MA was higher than that of FBG (P<0.05). The detection sensitivity of R value of TEG in patients with thrombosis was higher than that of PT and APTT, and the detection sensitivity of Angle was higher than that of FBG, while the detection sensitivity of K value and MA was lower than that of FBG.Conclusion Thrombelastogram and conventional coagulation have a certain correlation in the detection of coagulation function in patients, but the sensitivity of the two methods for detecting thrombosis and bleeding is low, and the consistency is relatively weak.However, the sensitivity of thromboelastography is relatively better than that of three tests of conventional coagulation, which can better reflect the coagulation process of patients.

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更新日期/Last Update: 1900-01-01