[1]林 苗,余怡红.宫腔镜电切术联合左炔诺孕酮宫内缓释系统的临床疗效分析[J].医学信息,2022,35(22):121-123.[doi:10.3969/j.issn.1006-1959.2022.22.027]
　LIN Miao,YU Yi-hong.Analysis of Clinical Efficacy of Transcervical Resection Of Endometrialpolyps Combined with Levonorgestrel Intrauterine Sustained Release System[J].Journal of Medical Information,2022,35(22):121-123.[doi:10.3969/j.issn.1006-1959.2022.22.027]
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宫腔镜电切术联合左炔诺孕酮宫内缓释系统的临床疗效分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年22期
页码:
121-123
栏目:
临床研究
出版日期:
2022-11-15

文章信息/Info

Title:
Analysis of Clinical Efficacy of Transcervical Resection Of Endometrialpolyps Combined with Levonorgestrel Intrauterine Sustained Release System
文章编号:
1006-1959（2022）22-0121-03
作者:
林 苗; 余怡红
（上饶市广信区人民医院妇产科，江西 上饶 334000）
Author(s):
LIN Miao; YU Yi-hong
(Department of Obstetrics and Gynecology,Shangrao Guangxin District People’s Hospital,Shangrao 334000,Jiangxi,China)
关键词:
子宫内膜息肉; 宫腔镜电切术; 左炔诺孕酮宫内缓释系统; 生殖激素
Keywords:
Endometrial polyps; Transcervical resection of endometrialpolyps; Levonorgestrel-releasing intrauterine system; Reproductive hormones
分类号:
R713.4
DOI:
10.3969/j.issn.1006-1959.2022.22.027
文献标志码:
A
摘要:
目的 分析宫腔镜电切术（TCRP）联合左炔诺孕酮宫内缓释系统（LNG-IUS）治疗子宫内膜息肉（EP）的临床疗效。方法 选取2019年6月-2021年4月上饶市广信区人民医院收治的78例EP患者为研究对象，采用随机数字表法分为对照组与观察组，各39例。对照组给予TCRP治疗，观察组给予TCRP联合LNG-IUS治疗，比较两组子宫内膜厚度、生殖激素水平[血清卵泡刺激素（FSH）、雌二醇（E2）、孕酮（P）]、经期视觉模拟评分（VAS）、血红蛋白水平、不良反应及复发情况。结果 两组治疗后子宫内膜厚度均有所减小，且观察组治疗后3个月及6个月的子宫内膜厚度小于对照组（P＜0.05）；两组治疗后FSH、E2、P水平变化比较，差异无统计学意义（P＞0.05）；两组治疗后3个月经期VAS评分低于治疗前，血红蛋白水平高于治疗前，且观察组经期VAS评分低于对照组，血红蛋白水平高于对照组（P＜0.05）；两组不良反应发生率比较，差异无统计学意义（P＞0.05）；观察组复发率小于对照组（P＜0.05）。结论 TCRP联合LNG-IUS应用于EP治疗中，可有效减小患者子宫内膜厚度，改善其痛经症状，提升血红蛋白水平，且不影响患者的血清孕激素指标，安全性高，不易复发。
Abstract:
Objective To analyze the clinical efficacy of transcervical resection of endometrialpolyps (TCRP) combined with levonorgestrel-releasing intrauterine system (LNG-IUS) in the treatment of endometrial polyps (EP).Methods A total of 78 EP patients admitted to Guangxin District People’s Hospital of Shangrao City from June 2019 to April 2021 were selected as the research objects. They were divided into control group and observation group by random number table method, with 39 cases in each group. The control group was treated with TCRP, and the observation group was treated with TCRP combined with LNG-IUS. The endometrial thickness, reproductive hormone levels [serum follicle stimulating hormone (FSH), estradiol (E2), progesterone (P)], menstrual visual analogue scale (VAS), hemoglobin level, adverse reactions and recurrence were compared between the two groups.Results The endometrial thickness of the two groups decreased after treatment, and the endometrial thickness of the observation group was smaller than that of the control group at 3 months and 6 months after treatment (P<0.05). There was no significant difference in the levels of FSH, E2 and P between the two groups after treatment (P>0.05). The VAS score of the two groups at 3 months after treatment was lower than that before treatment, and the hemoglobin level was higher than that before treatment, while the VAS score of the observation group was lower than that of the control group, and the hemoglobin level was higher than that of the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). The recurrence rate of the observation group was lower than that of the control group (P<0.05).Conclusion TCRP combined with LNG-IUS can effectively reduce the endometrial thickness of patients, improve the symptoms of dysmenorrhea, increase the level of hemoglobin, and does not affect the serum progesterone indexes of patients, with high safety and less recurrence.

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更新日期/Last Update: 1900-01-01