[1]解艳欢,阎丽娜,徐 祯.尿毒清联合金水宝对慢性肾功能不全患者电解质水平及蛋白代谢的影响[J].医学信息,2022,35(24):133-135.[doi:10.3969/j.issn.1006-1959.2022.24.027]
　XIE Yan-huan,YAN Li-na,XU Zhen.Effect of Niaoduqing Combined with Jinshuibao on Electrolyte Level and Protein Metabolism in Patients with Chronic Renal Insufficiency[J].Journal of Medical Information,2022,35(24):133-135.[doi:10.3969/j.issn.1006-1959.2022.24.027]
点击复制

尿毒清联合金水宝对慢性肾功能不全患者电解质水平及蛋白代谢的影响()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年24期
页码:
133-135
栏目:
药物与临床
出版日期:
2022-12-15

文章信息/Info

Title:
Effect of Niaoduqing Combined with Jinshuibao on Electrolyte Level and Protein Metabolism in Patients with Chronic Renal Insufficiency
文章编号:
1006-1959（2022）24-0133-03
作者:
解艳欢; 阎丽娜; 徐 祯
（天津市西青医院肾内科，天津 300380）
Author(s):
XIE Yan-huan; YAN Li-na; XU Zhen
(Department of Nephrology,Tianjin Xiqing Hospital,Tianjin 300380,China)
关键词:
肾功能不全; 电解质; 蛋白代谢; 尿酸
Keywords:
Renal insufficiency; Electrolyte; Protein metabolism; Uric acid
分类号:
R692
DOI:
10.3969/j.issn.1006-1959.2022.24.027
文献标志码:
A
摘要:
目的 评价慢性肾功能不全患者应用金水宝联合尿毒清治疗后蛋白质代谢、电解质指标的改善情况。方法 选取2017年10月-2021年10月在我院治疗的80例慢性肾功能不全患者，依据随机数字表法分为对照组、联合用药组，每组40例。对照组给予尿毒清口服治疗，联合用药组在对照组基础上给予金水宝片口服治疗，比较两组血清Ca2+、P3-、K+电解质指标、24 h尿蛋白、肾功能指标（肌酐清除率、血尿素氮、血清肌酐及尿酸）及临床疗效。结果 联合用药组血Ca2+高于对照组，血P3-、K+低于对照组（P＜0.05）；联合用药组24 h尿蛋白、尿酸、血尿素氮、血清肌酐低于对照组，肌酐清除率高于对照组（P＜0.05）；联合用药组总有效率高于对照组（P＜0.05）。结论 金水宝联合尿毒清可以改善慢性肾功能不全患者蛋白质代谢、电解质、肾功能指标，提高临床疗效，值得应用。
Abstract:
Objective To evaluate the improvement of protein metabolism and electrolyte indexes in patients with chronic renal insufficiency after treatment with Jinshuibao combined with Niaoduqing.Methods Eighty patients with chronic renal insufficiency treated in our hospital from October 2017 to October 2021 were selected and divided into control group and combination group according to random number table method, with 40 cases in each group. The control group was treated with Niaoduqing orally, and the combination group was treated with Jinshuibao tablets orally on the basis of the control group. The serum Ca2+, P3-, K+ electrolyte indexes, 24 h urine protein, renal function indexes (creatinine clearance rate, blood urea nitrogen, serum creatinine and uric acid) and clinical efficacy were compared between the two groups.Results The blood Ca2+ in the combination group was higher than that in the control group, and the blood P3- and K+ were lower than those in the control group (P<0.05). The 24 h urine protein, uric acid, blood urea nitrogen and serum creatinine in the combination group were lower than those in the control group, and the creatinine clearance rate was higher than that in the control group (P<0.05). The total effective rate of the combination group was higher than that of the control group (P<0.05).Conclusion Jinshuibao combined with Niaoduqing can improve protein metabolism, electrolyte and renal function indexes in patients with chronic renal insufficiency, improve clinical efficacy, and is worthy of application.

参考文献/References:

[1]徐殊,陶登顺,赵科研,等.不同程度慢性肾功能不全对冠心病患者非体外循环冠状动脉旁路移植术后早期疗效的影响对比[J].广西医学,2021,43(1):7-10.[2]陈国飞,王韧舟,刘小玲,等.固肾汤联合常规治疗对慢性肾功能不全患者的临床疗效[J].中成药,2021,43(3):830-832.[3]张雪冰,康省,荀靖琼.非透析男性慢性肾功能不全患者血清胰岛素样生长因子1、内皮素1与骨代谢指标的相关性研究[J].国际检验医学杂志,2021,42(9):1033-1036.[4]Charles C,Ferris AH.Chronic Kidney Disease[J].Prim Care,2020,47(4):585-595.[5]陈鸿钰,黎芳名,曾丽梅.血液灌流联合血液透析与血液透析滤过治疗老年慢性肾功能不全的疗效分析[J].临床肾脏病杂志,2021,21(7):529-534.[6]Ruiz-Ortega M,Rayego-Mateos S,Lamas S,et al.Targeting the progression of chronic kidney disease[J].Nat Rev Nephrol,2020,16(5):269-288.[7]崔青丽.慢性肾功能不全Ⅳ期患者腹膜透析后发生肾性贫血的影响因素[J].河南医学研究,2021,30(14):2616-2618.[8]Wang YN,Ma SX,Chen YY,et al.Chronic kidney disease: Biomarker diagnosis to therapeutic targets[J].Clin Chim Acta,2019,499:54-63.[9]刘帮燕,赵丽霞,郑曙光,等.超声多参数评分诊断慢性肾病[J].中国医学影像技术,2021,37(2):273-277.[10]Walther CP,Nambi V,Hanania NA,et al.Diagnosis and Management of Pulmonary Hypertension in Patients With CKD[J].Am J Kidney Dis,2020,75(6):935-945.[11]王海军,郭艳,司全金,等.慢性肾功能不全对中老年非瓣膜性房颤患者全因死亡、心脑血管疾病死亡及血栓终点事件的影响[J].中国应用生理学杂志,2018,34(3):209-215.[12]Anderson CAM,Nguyen HA.Nutrition education in the care of patients with chronic kidney disease and end-stage renal disease[J].Semin Dial,2018,31(2):115-121.[13]黄敏,王楠,成水芹,等.碳酸镧联合碳酸钙片对慢性肾功能不全高磷血症患者钙磷代谢的影响[J].海军医学杂志,2021,42(2):180-183.[14]李静.不同时机血液灌流联合血液透析治疗慢性肾功能不全的效果比较[J].河南医学研究,2021,30(14):2589-2591.[15]熊建,张博禹,韩权,等.合并慢性肾功能不全骨质疏松性骨折患者的围术期治疗[J].解放军医学杂志,2019,44(2):137-141.[16]Tangren J,Nadel M,Hladunewich MA.Pregnancy and End-Stage Renal Disease[J].Blood Purif,2018,45(1-3):194-200.[17]李娟,蒙向欣,赵威,等.五仁润肠加味汤治疗痛风性肾脏病变伴慢性肾功能不全[J].世界中医药,2020,15(8):1167-1170.[18]Vilay AM.Antibiotic Dosing in Chronic Kidney Disease and End-Stage Renal Disease: A Focus on Contemporary Challenges[J].Adv Chronic Kidney Dis,2019,26(1):61-71.[19]程红卫,成晓萍.阎晓萍从脾论治糖尿病肾病经验总结[J].陕西中医,2019,40(6):790-792.[20]祝亮,鲁庆红,王志芳,等.尿毒清颗粒对早中期慢性肾衰竭微炎症状态的作用[J].中华中医药学刊,2018,36(6):1474-1477.[21]葛红娣.尿毒清颗粒联合左卡尼汀对维持性血液透析患者营养不良、微炎症状态及生活质量的影响[J].河北医药,2021,43(9):1396-1398.

相似文献/References:

[1]韦能宝,薛志刚,毕金文.尿源性脓毒血症诊治分析[J].医学信息,2018,31(24):170.[doi:10.3969/j.issn.1006-1959.2018.24.052]
　WEI Neng-bao,XUE Zhi-gang,BI Jin-wen.Diagnosis and Treatment of Urinary Sepsis[J].Journal of Medical Information,2018,31(24):170.[doi:10.3969/j.issn.1006-1959.2018.24.052]
[2]张 明,李 超,谷海飞.不同晶体液对胃肠道手术婴儿电解质、血糖的影响[J].医学信息,2019,32(01):69.[doi:10.3969/j.issn.1006-1959.2019.01.023]
　ZHANG Ming,LI Chao,GU Hai-fei.Effects of Different Crystalloids on Electrolytes and Blood Glucose in Infants Undergoing Gastrointestinal Surgery[J].Journal of Medical Information,2019,32(24):69.[doi:10.3969/j.issn.1006-1959.2019.01.023]
[3]薄 慧.儿童矮小症血液电解质及微量元素与体格发育[J].医学信息,2019,32(23):55.[doi:10.3969/j.issn.1006-1959.2019.23.015]
　BO Hui.Blood Electrolytes,Trace Elements and Physical Development in Children with Short Stature[J].Journal of Medical Information,2019,32(24):55.[doi:10.3969/j.issn.1006-1959.2019.23.015]
[4]叶廷巧,赵 亮,庾 辉,等.托伐普坦治疗心力衰竭合并肾功能不全的研究[J].医学信息,2020,33(15):69.[doi:10.3969/j.issn.1006-1959.2020.15.022]
　YE Ting-qiao,ZHAO Liang,YU Hui,et al.Tolvaptan in the Treatment of Heart Failure with Renal Insufficiency[J].Journal of Medical Information,2020,33(24):69.[doi:10.3969/j.issn.1006-1959.2020.15.022]
[5]毛 锋.标本溶血对生化检验中电解质、心肌酶、肝功能、血脂水平的影响[J].医学信息,2020,33(19):173.[doi:10.3969/j.issn.1006-1959.2020.19.056]
　MAO Feng.The Effect of Specimen Hemolysis on Electrolytes,Myocardial Enzymes, Liver Functionand Blood Lipid Levels in Biochemical Tests[J].Journal of Medical Information,2020,33(24):173.[doi:10.3969/j.issn.1006-1959.2020.19.056]
[6]曾环峰,孙 杰.慢性阻塞性肺疾病合并肾功能不全的关系研究[J].医学信息,2022,35(13):46.[doi:10.3969/j.issn.1006-1959.2022.13.009]
　ZENG Huan-feng,SUN Jie.Study on the Relationship Between Chronic Obstructive Pulmonary Disease and Renal Insufficiency[J].Journal of Medical Information,2022,35(24):46.[doi:10.3969/j.issn.1006-1959.2022.13.009]

更新日期/Last Update: 1900-01-01