参考文献/References:
[1]Barnett R.Osteoarthritis[J].Lancet,2018,391(10134):1985.[2]Sacitharan PK.Ageing and Osteoarthritis[J].Subcell Biochem,2019,91:123-159.[3]Abramoff B,Caldera FE.Osteoarthritis: Pathology, Diagnosis, and Treatment Options[J].Med Clin North Am,2020,104(2):293-311.[4]Sharma L.Osteoarthritis of the Knee[J].N Engl J Med,2021,384(1):51-59.[5]Fang T,Zhou X,Jin M,et al.Molecular mechanisms of mechanical load-induced osteoarthritis[J].Int Orthop,2021,45(5):1125-1136.[6]Nakamura A,Rampersaud YR,Nakamura S,et al.microRNA-181a-5p antisense oligonucleotides attenuate osteoarthritis in facet and knee joints[J].Ann Rheum Dis,2019,78(1):111-121.[7]Xie R,Yao H,Mao AS,et al.Biomimetic cartilage-lubricating polymers regenerate cartilage in rats with early osteoarthritis[J].Nat Biomed Eng,2021,5(10):1189-1201.[8]Feucht MJ,Izadpanah K,Vogt S,et al.Stellenwert der chirurgischen Knorpeltherapie bei Früharthrose [Cartilage repair procedures for early osteoarthritis][J].Orthopade,2021,50(5):356-365.[9]Masood N,Dubey V,Luqman S.Activation of Caspase-3 by Terpenoids and Flavonoids in Different Types of Cancer Cells[J].Curr Top Med Chem,2020,20(21):1876-1887.[10]Wang X,Pan J,Liu D,et al.Nicorandil alleviates apoptosis in diabetic cardiomyopathy through PI3K/Akt pathway[J].J Cell Mol Med,2019,23(8):5349-5359.[11]Teng Y,Fan Y,Ma J,et al.The PI3K/Akt Pathway: Emerging Roles in Skin Homeostasis and a Group of Non-Malignant Skin Disorders[J].Cells,2021,10(5):1219.[12]Vanhaesebroeck B,Perry MWD,Brown JR,et al.PI3K inhibitors are finally coming of age[J].Nat Rev Drug Discov,2021,20(10):741-769.[13]Spender LC,Inman GJ.Developments in Burkitt’s lymphoma: novel cooperations in oncogenic MYC signaling[J].Cancer Manag Res,2014,6:27-38.[14]Yeon JT,Kim KJ,Son YJ,et al.Idelalisib inhibits osteoclast differentiation and pre-osteoclast migration by blocking the PI3Kδ-Akt-c-Fos/NFATc1 signaling cascade[J].Arch Pharm Res,2019,42(8):712-721.[15]Li H,Marshall AJ.Phosphatidylinositol (3,4) bisphosphate-specific phosphatases and effector proteins: A distinct branch of PI3K signaling[J].Cell Signal,2015,27(9):1789-1798.[16]Mishra R,Patel H,Alanazi S,et al.PI3K Inhibitors in Cancer: Clinical Implications and Adverse Effects[J].Int J Mol Sci,2021,22(7):3464.[17]Hughes A,Oxford AE,Tawara K,et al.Endoplasmic Reticulum Stress and Unfolded Protein Response in Cartilage Pathophysiology; Contributing Factors to Apoptosis and Osteoarthritis[J].Int J Mol Sci,2017,18(3):665.[18]Shen J,Xu S,Zhou H,et al.IL-1β induces apoptosis and autophagy via mitochondria pathway in human degenerative nucleus pulposus cells[J].Sci Rep,2017,7:41067.[19]Depuydt B,van Loo G,Vandenabeele P,et al.Induction of apoptosis by TNF receptor 2 in a T-cell hybridoma is FADD dependent and blocked by caspase-8 inhibitors[J].J Cell Sci,2005,118(Pt 3):497-504.[20]Shi J,Zhang C,Yi Z,et al.Explore the variation of MMP3, JNK, p38 MAPKs, and autophagy at the early stage of osteoarthritis[J].IUBMB Life,2016,68(4):293-302.[21]Xu K,He Y,Moqbel SAA,et al.SIRT3 ameliorates osteoarthritis via regulating chondrocyte autophagy and apoptosis through the PI3K/Akt/mTOR pathway[J].Int J Biol Macromol,2021,175:351-360.[22]Ma CH,Wu CH,Jou IM,et al.PKR Promotes Oxidative Stress and Apoptosis of Human Articular Chondrocytes by Causing Mitochondrial Dysfunction through p38 MAPK Activation-PKR Activation Causes Apoptosis in Human Chondrocytes[J].Antioxidants (Basel),2019,8(9):370.[23]Lee W,Nims RJ,Savadipour A,et al.Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis[J].Proc Natl Acad Sci U S A,2021,118(13):e2001611118.[24]李家驰,张德茂,谢静,等.成骨细胞-软骨细胞共培养通过MAPK信号上调软骨细胞HIF-1通路的研究[J].四川大学学报(医学版),2022,53(1):92-97.[25]Song CX,Liu SY,Zhu WT,et al.Excessive mechanical stretch mediated osteoblasts promote the catabolism and apoptosis of chondrocytes via the Wnt/β-catenin signaling pathway[J].Mol Med Rep,2021,24(2):593.[26]Chen T,Zhou R,Chen Y,et al.Curcumin ameliorates IL-1β-induced apoptosis by activating autophagy and inhibiting the NF-κB signaling pathway in rat primary articular chondrocytes[J].Cell Biol Int,2021,45(5):976-988.[27]王春玲,张瑜,文晓东,等.八月札乙醇提取物通过PI3K/Akt通路抑制H22细胞增殖并诱导其凋亡[J].中华中医药学刊,2022,40(9):73-77,267-268.[28]Noorolyai S,Shajari N,Baghbani E,et al.The relation between PI3K/AKT signalling pathway and cancer[J].Gene,2019,698:120-128.[29]高玲,赵建军,胡亚男,等.基于PI3K/Akt/Bad信号通路探讨益髓解毒方对血管性痴呆大鼠海马神经元凋亡的影响[J].中国实验方剂学杂志,2020,26(18):58-63.[30]Caramés B,Olmer M,Kiosses WB,et al.The relationship of autophagy defects to cartilage damage during joint aging in a mouse model[J].Arthritis Rheumatol,2015,67(6):1568-1576.[31]Sini P,James D,Chresta C,et al.Simultaneous inhibition of mTORC1 and mTORC2 by mTOR kinase inhibitor AZD8055 induces autophagy and cell death in cancer cells[J].Autophagy,2010,6(4):553-554.[32]Cayo A,Segovia R,Venturini W,et al.mTOR Activity and Autophagy in Senescent Cells, a Complex Partnership[J].Int J Mol Sci,2021,22(15):8149.[33]Usman RM,Razzaq F,Akbar A,et al.Role and mechanism of autophagy-regulating factors in tumorigenesis and drug resistance[J].Asia Pac J Clin Oncol,2021,17(3):193-208.[34]Valenti MT,Dalle Carbonare L,Zipeto D,et al.Control of the Autophagy Pathway in Osteoarthritis: Key Regulators, Therapeutic Targets and Therapeutic Strategies[J].Int J Mol Sci,2021,22(5):2700.[35]Tian Z,Zhang X,Sun M.Phytochemicals Mediate Autophagy Against Osteoarthritis by Maintaining Cartilage Homeostasis[J].Front Pharmacol,2021,12:795058.[36]Zhang Y,Vasheghani F,Li YH,et al.Cartilage-specific deletion of mTOR upregulates autophagy and protects mice from osteoarthritis[J].Ann Rheum Dis,2015,74(7):1432-1440.[37]Shi X,Han L,Sun T,et al.Silencing UHRF1 enhances cell autophagy to prevent articular chondrocytes from apoptosis in osteoarthritis through PI3K/AKT/mTOR signaling pathway[J].Biochem Biophys Res Commun,2020,529(4):1018-1024.[38]Yu M,Qi B,Xiaoxiang W,et al.Baicalein increases cisplatin sensitivity of A549 lung adenocarcinoma cells via PI3K/Akt/NF-κB pathway[J].Biomed Pharmacother,2017,90:677-685.[39]杨鑫,李源力,蒋萍,等.杨梅素通过PI3K/AKT/NF-κB信号通路对骨性关节炎发展的影响[J].暨南大学学报（自然科学与医学版）,2020,41(1):48-57.[40]Lu H,Zhang LH,Yang L,et al.The PI3K/Akt/FOXO3a pathway regulates regeneration following spinal cord injury in adult rats through TNF-α and p27kip1 expression[J].Int J Mol Med,2018,41(5):2832-2838.[41]Lin C,Shao Y,Zeng C,et al.Blocking PI3K/AKT signaling inhibits bone sclerosis in subchondral bone and attenuates post-traumatic osteoarthritis[J].J Cell Physiol,2018,233(8):6135-6147.[42]Erira A,Velandia F,Penagos J,et al.Differential Regulation of the EGFR/PI3K/AKT/PTEN Pathway between Low- and High-Grade Gliomas[J].Brain Sci,2021,11(12):1655.[43]朱思行,严世芸,徐燕,等.基于PI3K/Akt/Caspase-9信号通路研究严氏强心饮对心力衰竭大鼠心肌细胞凋亡的影响[J].康复学报,2022,32(2):131-139.[44]Huang R,Hui Z,Wei S,et al.IRE1 signaling regulates chondrocyte apoptosis and death fate in the osteoarthritis[J].J Cell Physiol,2022,237(1):118-127.[45]Hajka D,Budziak B,Pietras ?覵,et al.GSK3 as a Regulator of Cytoskeleton Architecture: Consequences for Health and Disease[J].Cells,2021,10(8):2092.[46]Huang PY,Wu JG,Gu J,et al.Bioinformatics analysis of miRNA and mRNA expression profiles to reveal the key miRNAs and genes in osteoarthritis[J].J Orthop Surg Res,2021,16(1):63.[47]An X,Wang T,Zhang W,et al.Chondroprotective Effects of Combination Therapy of Acupotomy and Human Adipose Mesenchymal Stem Cells in Knee Osteoarthritis Rabbits via the GSK3β-Cyclin D1-CDK4/CDK6 Signaling Pathway[J].Aging Dis,2020,11(5):1116-1132.
相似文献/References:
[1]韩少锋.独活寄生汤配合玻璃酸钠对膝骨关节炎患者生活质量的影响[J].医学信息,2018,31(14):159.[doi:10.3969/j.issn.1006-1959.2018.14.049]
HAN Shao-feng.Effect of Duhuo Jisheng Decoction Combined with Sodium Hyaluronate on Quality of Life in Patients with Knee Osteoarthritis[J].Journal of Medical Information,2018,31(20):159.[doi:10.3969/j.issn.1006-1959.2018.14.049]
[2]赵懋宇.玻璃酸钠治疗膝关节骨性关节炎的疗效观察[J].医学信息,2019,32(01):112.[doi:10.3969/j.issn.1006-1959.2019.01.034]
ZHAO Mao-yu.Therapeutic Effect of Sodium Hyaluronate on Knee Osteoarthritis[J].Journal of Medical Information,2019,32(20):112.[doi:10.3969/j.issn.1006-1959.2019.01.034]
[3]吴 刚,陈腊梅.附桂骨痛片联合艾瑞昔布片及氟比洛芬巴布膏
治疗膝骨关节炎的临床研究[J].医学信息,2019,32(14):158.[doi:10.3969/j.issn.1006-1959.2019.14.053]
WU Gang,CHEN La-mei.Clinical Study on Treatment of Knee Osteoarthritis with Fuguigutong Tablets Combined with
Ericoxib Tablets and Flurbiprofen Bab Cream[J].Journal of Medical Information,2019,32(20):158.[doi:10.3969/j.issn.1006-1959.2019.14.053]
[4]梁子聪,王 恒,胡先运,等.鹿角壮骨胶囊对膝骨关节炎兔血清及软骨IL-6、MMP-3的影响[J].医学信息,2020,33(01):61.[doi:10.3969/j.issn.1006-1959.2020.01.020]
LIANG Zi-cong,WANG Heng,HU Xian-yun,et al.Effects of Lujiao Zhuanggu Capsule on Serum and Cartilage IL-6 and MMP-3 in Rabbits with Knee Osteoarthritis[J].Journal of Medical Information,2020,33(20):61.[doi:10.3969/j.issn.1006-1959.2020.01.020]
[5]蒋 磊,苏 程,葛 军,等.膝骨关节炎危险因素研究[J].医学信息,2020,33(15):30.[doi:10.3969/j.issn.1006-1959.2020.15.011]
JIANG Lei,SU Cheng,GE Jun,et al.Study on Risk Factors of Knee Osteoarthritis[J].Journal of Medical Information,2020,33(20):30.[doi:10.3969/j.issn.1006-1959.2020.15.011]
[6]陈飞跃,黄肖华,邹明辉.膝骨关节炎的中医药综合疗法研究概况[J].医学信息,2020,33(19):41.[doi:10.3969/j.issn.1006-1959.2020.19.013]
CHEN Fei-yue,HUANG Xiao-hua,ZOU Ming-hui.General Situation of Comprehensive Therapy of Traditional Chinese Medicine for Knee Osteoarthritis[J].Journal of Medical Information,2020,33(20):41.[doi:10.3969/j.issn.1006-1959.2020.19.013]
[7]张博闻,赵其纯.开放式胫骨高位截骨术治疗膝骨关节炎合并膝内翻的效果[J].医学信息,2021,34(01):129.[doi:10.3969/j.issn.1006-1959.2021.01.034]
ZHANG Bo-wen,ZHAO Qi-chun.The Effect of Open High Tibial Osteotomy on Knee Osteoarthritis Complicated with Knee Varus[J].Journal of Medical Information,2021,34(20):129.[doi:10.3969/j.issn.1006-1959.2021.01.034]
[8]王立刚.单髁置换术治疗老年膝骨关节炎患者的效果及对膝关节功能的影响[J].医学信息,2021,34(11):124.[doi:10.3969/j.issn.1006-1959.2021.11.034]
WANG Li-gang.The Effect of Unicondylar Replacement in the Treatment of Elderly Patients with Knee Osteoarthritis and Its Influence on Knee Joint Function[J].Journal of Medical Information,2021,34(20):124.[doi:10.3969/j.issn.1006-1959.2021.11.034]