[1]邵俊丽.静息心率与脑卒中关系的研究[J].医学信息,2018,31(16):16-20.[doi:10.3969/j.issn.1006-1959.2018.16.006]
 SHAO Jun-li.Research on Relationship between Resting Heart Rate and Stroke[J].Journal of Medical Information,2018,31(16):16-20.[doi:10.3969/j.issn.1006-1959.2018.16.006]
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静息心率与脑卒中关系的研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
31卷
期数:
2018年16期
页码:
16-20
栏目:
综述
出版日期:
2018-08-15

文章信息/Info

Title:
Research on Relationship between Resting Heart Rate and Stroke
文章编号:
1006-1959(2018)16-0016-05
作者:
邵俊丽
江苏无锡长江康复医院医疗康复科,江苏 无锡 214002
Author(s):
SHAO Jun-li
Department of Medical Rehabilitation,Changjiang Rehabilitation Hospital,Wuxi 214002,Jiangsu,China
关键词:
静息心率脑卒中β受体阻滞剂
Keywords:
Key words:Resting heart rateStrokeβ receptor blockers
分类号:
R743.3
DOI:
10.3969/j.issn.1006-1959.2018.16.006
文献标志码:
A
摘要:
静息心率与脑卒中相关危险因素,包括高血压、脂代谢异常、糖尿病、颈动脉粥样硬化性疾病等各方面均密切相关。机制在于交感神经过度激活,改变血压的昼夜节律、血流剪切力升高长期作用、颈动脉内-中膜的增厚相关、血管的内皮功能受损、各种炎症标志物、血管内斑块的形成等。治疗上,各大指南共识在原发疾病的基础上均确定了目标心率。β受体阻滞剂在降压治疗的同时可减慢心率,但要注意应个体化处理。静息心率是高血压患者预后的独立预测因子,降低静息心率可减少脑卒中的发生率及远期预后。
Abstract:
Abstract:Resting heart rate is closely related to stroke-related risk factors,including hypertension,dyslipidemia,diabetes,carotid atherosclerosis and so on.The mechanism lies in over-activation of the sympathetic nerve,changing the circadian rhythm of blood pressure,long-term effect of elevated blood flow shear stress,thickening of the carotid intima-media,impaired vascular endothelial function,various inflammatory markers,formation of intravascular plaques and so on.In terms of treatment,it is agreed that the target heart rate is determined on the basis of primary diseases.β receptor blockers can slow down heart rate while lowering blood pressure, but individual treatment should be paid attention to.Resting heart rate is an independent predictor of prognosis in patients with hypertension.Decreasing resting heart rate can reduce the incidence of stroke and long-term prognosis.

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更新日期/Last Update: 2018-08-15