[1]肖辛怡,严玉宁,魏文石.轻度行为损害的研究[J].医学信息,2019,32(13):49-51.[doi:10.3969/j.issn.1006-1959.2019.13.015]
　XIAO Xin-yi,YAN Yu-ning,WEI Wen-shi.The Research of Mild Behavioral Damage[J].Journal of Medical Information,2019,32(13):49-51.[doi:10.3969/j.issn.1006-1959.2019.13.015]
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轻度行为损害的研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年13期
页码:
49-51
栏目:
综述
出版日期:
2019-07-01

文章信息/Info

Title:
The Research of Mild Behavioral Damage
文章编号:
1006-1959（2019）13-0049-03
作者:
肖辛怡1; 严玉宁2; 魏文石2
1.苏州大学附属第一医院神经内科，江苏 苏州 215000； 2.复旦大学附属华东医院神经内科，上海 200040
Author(s):
XIAO Xin-yi1; YAN Yu-ning2; WEI Wen-shi2
1.Department of Neurology,the First Affiliated Hospital of Suzhou University,Suzhou 215000,Jiangsu,China; 2.Department of Neurology,Huadong Hospital,Fudan University,Shanghai 200040,China
关键词:
轻度行为损害; 痴呆; 轻度认知障碍; 精神行为症状
Keywords:
Key words：Mild behavioral impairment; Dementia; Mild cognitive impairment; Mental behavioral symptoms
分类号:
R749.1
DOI:
10.3969/j.issn.1006-1959.2019.13.015
文献标志码:
A
摘要:
精神症状对认知下降的出现及进展具有警示作用，近年来对轻度行为损害（MBI）状态愈加重视，为已有精神行为症状，而尚无明显认知损害这一特殊阶段提供了落脚点，其预测进展为痴呆的效能甚至高于海马萎缩等生物标志物。本文简述了MBI概念的产生，阐释了定义及诊断标准，总结回顾截至目前的相关研究，旨在明确其有效性及便捷性，同时介绍了其配套的评估量表。应用MBI这一诊断，可以在神经退行性疾病前驱期、亚临床期对精神症状进行评定，再者可以形成一个广泛认可的概念性术语，给疾病分类学、流行病学、神经生物学研究和痴呆的治疗、预防提供了很大的便捷。
Abstract:
Abstract：Psychiatric symptoms have a warning effect on the emergence and progression of cognitive decline. In recent years, more attention has been paid to the state of mild behavioral impairment (MBI), which provides a special stage of mental behavioral symptoms without significant cognitive impairment. At the footing, its predictive progress to dementia is even higher than biomarkers such as hippocampal atrophy. This article briefly describes the emergence of the MBI concept, explains the definitions and diagnostic criteria, summarizes the relevant research to date, aims to clarify its effectiveness and convenience, and introduces its supporting assessment scale. With the diagnosis of MBI, mental symptoms can be assessed in the prodromal and subclinical stages of neurodegenerative diseases, and a widely accepted conceptual term can be formed for disease taxonomy, epidemiology, neurobiology research, the treatment and prevention of dementia, all of them has provides great convenience.

参考文献/References:

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更新日期/Last Update: 2019-07-01