[1]刘佳生.后腹腔镜根治术对肾癌患者ACTH、Cor水平的影响[J].医学信息,2020,33(10):124-125.[doi:10.3969/j.issn.1006-1959.2020.10.035]
　LIU Jia-sheng.The Effect of Retroperitoneal Laparoscopic Radical Operation on ACTH and Cor[J].Medical Information,2020,33(10):124-125.[doi:10.3969/j.issn.1006-1959.2020.10.035]
点击复制

后腹腔镜根治术对肾癌患者ACTH、Cor水平的影响()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年10期
页码:
124-125
栏目:
临床研究
出版日期:
2020-05-15

文章信息/Info

Title:
The Effect of Retroperitoneal Laparoscopic Radical Operation on ACTH and Cor
文章编号:
1006-1959（2020）10-0124-02
作者:
刘佳生
（佳木斯市中心医院泌尿外科，黑龙江 佳木斯 154002）
Author(s):
LIU Jia-sheng
(Urology Department,Jiamusi Central Hospital,Jiamusi 154002,Heilongjiang,China)
关键词:
肾癌; 后腹腔镜根治术; 促肾上腺皮质激素; 皮质醇
Keywords:
Renal cancer; Posterior laparoscopic radical resection; Adrenocorticotropic hormone; Cortisol
分类号:
R737.11
DOI:
10.3969/j.issn.1006-1959.2020.10.035
文献标志码:
A
摘要:
目的 探讨后腹腔镜根治术对肾癌患者促肾上腺皮质激素（ACTH）、皮质醇（Cor）水平的影响。方法 回顾性分析2018年4月~2019年5月我院收治的84例肾癌患者临床资料，依据手术方式分为对照组与观察组，每组42例。对照组行开放性肾癌根治术，观察组行后腹腔镜根治术，比较两组围术期指标（术中出血量、手术时间、首次下床活动时间及住院时间）、ACTH及Cor水平。结果 观察组术中出血量、手术时间、首次下床活动时间及住院时间均短于对照组，差异有统计学意义（P＜0.05）；两组治疗5 d后ACTH与Cor水平均较术前升高，但观察组较对照组低[（55.47±10.03）g/ml vs （91.52±10.46）g/ml]、[（163.24±34.51）ng/ml vs （236.13±37.48）ng/ml]，差异有统计学意义（P＜0.05）。结论 肾癌患者行后腹腔镜根治术治疗可减少术中出血量，缩短手术用时、首次下床活动时间及住院时间，降低ACTH、Cor水平。
Abstract:
Objective To investigate the effect of retroperitoneal laparoscopic radical surgery on the levels of (ACTH) and Cortisol (Cor) in patients with renal cell carcinoma.Methods The clinical data of 84 kidney cancer patients admitted to our hospital from April 2018 to May 2019 were retrospectively analyzed, according to the operation method, it was divided into a control group and an observation group, with 21 patients in each. The control group underwent open radical nephrectomy, and the observation group underwent retroperitoneal laparoscopic radical resection. The perioperative indicators (intraoperative blood loss, operation time, first time out of bed and hospital stay), ACTH and Cor levels were compared between the two groups.Results The intraoperative blood loss, operation time, first time out of bed and hospitalization time of the observation group were shorter than that of the control group, the difference was statistically significant (P<0.05);After 5 d of treatment, the levels of ACTH and Cor in the two groups were higher than before surgery, but the observation group was lower than the control group [(55.47±10.03) g/ml vs (91.52±10.46) g/ml], [(163.24±34.51) ng/ml vs (236.13±37.48) ng/ml], the difference was statistically significant (P<0.05).Conclusion Laparoscopic radical surgery for patients with renal cell carcinoma can reduce intraoperative bleeding, shorten the operation time, the first time out of bed and the total hospital stay, and reduce ACTH and Cor levels.

参考文献/References:

[1]谢圣陶,陈广瑜,魏乔红,等.后腹腔镜根治性肾切除术与开放手术治疗T2期肾癌的临床疗效和安全性比较[J].国际泌尿系统杂志,2018,38(6):926-928.[2]黄秀川,潘连洪,余传杰.微创手术对局限性原发性肾癌患者免疫与神经内分泌功能的影响[J].检验医学与临床,2016,13(10):1370-1372.[3]葛学凯,周文生.后腹腔镜与开放肾癌根治术治疗局限性肾癌的临床疗效比较[J].中华全科医学,2016,14(10):1651-1653.[4]高旭,刘安.后腹腔镜根治性肾切除术治疗局限性肾癌的疗效研究[J].实用癌症杂志,2017,32(2):339-341.[5]王晓晶,何威,何竑超,等.促肾上腺皮质激素非依赖性肾上腺大结节增生的治疗效果分析[J].中华泌尿外科杂志,2017,38(4):252-255.[6]武燕龙,包国昌,高志明.后腹腔镜肾癌根治术对肾癌患者应激指标、肿瘤标志物及肾功能的影响[J].海南医学院学报,2019,25(7):502-505.

相似文献/References:

[1]熊波波,张劲松,王海峰,等.miRNAs与泌尿系肿瘤关系的研究进展[J].医学信息,2019,32(05):35.[doi:10.3969/j.issn.1006-1959.2019.04.013]
　XIONG Bo-bo,ZHANG Jin-song,WANG Hai-feng,et al.Research Progress on the Relationship between miRNAs and Urinary Tumors[J].Medical Information,2019,32(10):35.[doi:10.3969/j.issn.1006-1959.2019.04.013]
[2]刘佳生.腹腔镜下保留肾单位手术对肾癌患者sCD44v6、sICAM-1、β-EP水平的影响[J].医学信息,2020,33(14):117.[doi:10.3969/j.issn.1006-1959.2020.14.035]
　LIU Jia-sheng.Effect of Laparoscopic Nephron-sparing Operation on the Levels of sCD44v6,sICAM-1 and β-EP in Patients with Renal Cell Carcinoma[J].Medical Information,2020,33(10):117.[doi:10.3969/j.issn.1006-1959.2020.14.035]
[3]刘紫薇,刘市委,雷 磊,等.基于Web of Science关于肾癌预后研究的文献计量分析[J].医学信息,2022,35(15):14.[doi:10.3969/j.issn.1006-1959.2022.15.003]
　LIU Zi-wei,LIU Shi-wei,LEI Lei,et al.Bibliometric Analysis of Renal Cell Carcinoma Prognosis Based on Web of Science[J].Medical Information,2022,35(10):14.[doi:10.3969/j.issn.1006-1959.2022.15.003]

更新日期/Last Update: 2020-05-15