[1]李毓龙,刘 琴,黄倩倩.免疫球蛋白检测在乙型肝炎患者的应用价值[J].医学信息,2020,33(13):173-174.[doi:10.3969/j.issn.1006-1959.2020.13.055]
　LI Yu-long,LIU Qin,HUANG Qian-qian.Application Value of Immunoglobulin Detection in Patients with Hepatitis B[J].Medical Information,2020,33(13):173-174.[doi:10.3969/j.issn.1006-1959.2020.13.055]
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免疫球蛋白检测在乙型肝炎患者的应用价值()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年13期
页码:
173-174
栏目:
诊疗技术
出版日期:
2020-07-01

文章信息/Info

Title:
Application Value of Immunoglobulin Detection in Patients with Hepatitis B
文章编号:
1006-1959（2020）13-0173-02
作者:
李毓龙; 刘 琴; 黄倩倩
（简阳市人民医院检验科，四川 简阳 641400）
Author(s):
LI Yu-long; LIU Qin; HUANG Qian-qian
(Department of Laboratory,Jianyang People’s Hospital,Jianyang 641400,Sichuan,China)
关键词:
免疫球蛋白检验; 乙型肝炎; 应用价值
Keywords:
Immunoglobulin test; Hepatitis B; Application value
分类号:
R446
DOI:
10.3969/j.issn.1006-1959.2020.13.055
文献标志码:
A
摘要:
目的 探究免疫球蛋白检验在乙型肝炎患者中的应用价值。方法 选取2018年9月~2019年8月我院收治的120例乙型肝炎患者，依据疾病类型将患者分为急性乙肝组、慢性乙肝组、慢性重型乙肝组及肝硬化组，每组30例；另选取同期在我院进行体检的60例健康者作为对照组，比较各组免疫球蛋白[免疫球蛋白G（IgG）、免疫球蛋白A（IgA）、免疫球蛋白M（IgM）、免疫球蛋白E（IgE）]检测结果。结果 急性乙肝组、慢性乙肝组、慢性重型乙肝组及肝硬化组血清IgA、IgG、IgM、IgE均高于对照组，差异有统计学意义（P＜0.05）；其中慢性重型乙型组各项免疫球蛋白指标水平最高，其次是肝硬化组、慢性乙肝组、急性乙肝组。结论 免疫球蛋白的水平随着病情的加重逐渐升高，以慢性重型乙肝患者最为突出，其可作为乙型肝炎患者肝功能检测的评判指标，对患者疾病的诊断、分型及预后具有非常重要的意义。
Abstract:
Objective To Explore the application value of immunoglobulin test in patients with hepatitis B.Methods 120 patients with hepatitis B admitted to our hospital from September 2018 to August 2019 were selected, and the patients were divided into acute hepatitis B group, chronic hepatitis B group, chronic severe hepatitis B group and cirrhosis group according to the type of disease, 30 cases in each group; In addition, 60 healthy people who were examined in our hospital during the same period were selected as the control group, and the results of immunoglobulin[immunoglobulin G (IgG), immunoglobulin A (IgA), immunoglobulin M (IgM), immunoglobulin E (IgE)] were compared between the groups.Results Serum IgA, IgG, IgM, IgE in acute hepatitis B group, chronic hepatitis B group, chronic severe hepatitis B group and cirrhosis group were higher than the control group, the difference was statistically significant (P<0.05); The level of globulin index was the highest, followed by cirrhosis group, chronic hepatitis B group, and acute hepatitis B group.Conclusion The level of immunoglobulin gradually increases with the aggravation of the disease, and it is most prominent in patients with chronic severe hepatitis B. It can be used as a judging indicator for liver function detection in patients with hepatitis B, and is very important for the diagnosis, classification and prognosis of patients’ diseases.

参考文献/References:

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更新日期/Last Update: 1900-01-01