[1]塔吉努尔·居来提,木亚斯尔·艾比布拉.儿童下呼吸道流感病毒感染危重症的临床特征分析[J].医学信息,2023,36(05):127-130.[doi:10.3969/j.issn.1006-1959.2023.05.024]
　Tajinuer·Julaiti,Muyasier·Aibibula.Analysis of Clinical Characteristics of Children with Severe Lower Respiratory Tract Influenza Virus Infection[J].Journal of Medical Information,2023,36(05):127-130.[doi:10.3969/j.issn.1006-1959.2023.05.024]
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儿童下呼吸道流感病毒感染危重症的临床特征分析()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年05期
页码:
127-130
栏目:
论著
出版日期:
2023-03-01

文章信息/Info

Title:
Analysis of Clinical Characteristics of Children with Severe Lower Respiratory Tract Influenza Virus Infection
文章编号:
1006-1959（2023）05-0127-04
作者:
塔吉努尔·居来提; 木亚斯尔·艾比布拉
（喀什地区第一人民医院儿童重症监护室，新疆 喀什 844000）
Author(s):
Tajinuer·Julaiti; Muyasier·Aibibula
(Department Of Pediatric Intensive Care Unit,the First People’s Hospital of Kashi Prefecture,Kashi 844000,Xinjiang,China)
关键词:
儿童; 下呼吸道感染; 流感病毒
Keywords:
Children; Lower respiratory tract infection; Influenza virus
分类号:
R725
DOI:
10.3969/j.issn.1006-1959.2023.05.024
文献标志码:
A
摘要:
目的 分析儿童下呼吸道流感病毒感染危重症的临床特征。方法 回顾分析2021年1月-2022年12月在我院诊治的84例下呼吸道流感病毒感染儿童临床资料，依据病情分为危重症患儿（31例）和普通患儿（53例），比较危重症患儿和普通患儿临床资料（年龄、性别、临床症状、实验室指标、发病季节、并发症、合并病原菌），总结危重症儿童下呼吸道流感病毒感染的临床特点，并采用多因素 Logistic 回归分析儿童下呼吸道流感病毒感染出现危重症的危险因素。结果 危重症患儿年龄、性别与普通患儿比较，差异有统计学意义（P＜0.05）；危重症患儿肺部湿罗音、咳嗽、气促发生率高于普通患儿（P＜0.05）；危重症C反应蛋白、中性粒细胞水平高于普通患儿，淋巴细胞计数、降钙素原低于普通患儿（P＜0.05）；危重症患儿冬季、秋季发生率高于普通患儿，夏季发生率低于普通患儿（P＜0.05）；危重症患儿合并肺炎、呼吸衰竭、肾功能不全比例高于普通患儿（P＜0.05）；危重症患儿痰液培养肺炎链球菌为主，肺炎克雷伯氏菌、EB病毒占比高于普通患儿（P＜0.05）；多因素非条件 Logistic 回归分析显示，＜5岁、男性、冬季、肺部湿罗音、中性粒细胞升高、合并肺炎、感染肺炎链球菌和EB病毒为儿童下呼吸道流感病毒感染出现危重症的危险因素。结论 临床下呼吸道流感病毒感染儿童中，危重症患儿多为5岁以下，且高发于冬季。同时临床对于普通患儿肺部出现湿罗音、中性粒细胞升高、合并肺炎，且感染肺炎链球菌和EB病毒时，应警惕危重症的发生，临床早期应及时给予抗病毒治疗，并密切观察合并症，以改善患儿预后。
Abstract:
Objective To analyze the clinical characteristics of critically ill children with lower respiratory tract influenza virus infection.Methods The clinical data of 84 children with lower respiratory tract influenza virus infection diagnosed and treated in our hospital from January 2021 to December 2022 were retrospectively analyzed. According to the condition, they were divided into critical children (31 cases) and ordinary children (53 cases). The clinical data (age, gender, clinical symptoms, laboratory indicators, season of onset, complications, combined pathogens) of critical children and ordinary children were compared, and the clinical characteristics of lower respiratory tract influenza virus infection in critical children were summarized. Multivariate Logistic regression analysis was used to analyze the risk factors of critical illness in children with lower respiratory tract influenza virus infection.Results There were significant differences in age and gender between critical children and ordinary children (P<0.05). The incidence of pulmonary moist rales, cough and shortness of breath in critical children was higher than that in ordinary children (P<0.05). The levels of C-reactive protein and neutrophils in critical children were higher than those in ordinary children, and the lymphocyte count and procalcitonin were lower than those in ordinary children (P<0.05). The incidence of critical children in winter and autumn was higher than that of ordinary children, and the incidence in summer was lower than that of ordinary children (P<0.05). The proportion of pneumonia, respiratory failure and renal insufficiency in critical children was higher than that in ordinary children (P<0.05). The sputum culture of critical children was mainly Streptococcus pneumoniae, and the proportion of Klebsiella pneumoniae and EB virus was higher than that of ordinary children(P<0.05).Conclusion Among children with clinical lower respiratory tract influenza virus infection, critical children are mostly under 5 years old, and the incidence is high in winter. At the same time, when the lungs of ordinary children have moist rales, elevated neutrophils, pneumonia, and infection with Streptococcus pneumoniae and EB virus, we should be alert to the occurrence of critical illness. Early clinical antiviral treatment should be given in time, and complications should be closely observed to improve the prognosis of children.

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更新日期/Last Update: 1900-01-01