[1]万玉峰.保乳术联合前哨淋巴结活检治疗早期三阴性乳腺癌的临床疗效[J].医学信息,2023,36(07):135-138.[doi:10.3969/j.issn.1006-1959.2023.07.026]
　WAN Yu-feng.Clinical Efficacy of Breast Conserving Surgery Combined with Sentinel Lymph Node Biopsy in the Treatment of Early Triple Negative Breast Cancer[J].Journal of Medical Information,2023,36(07):135-138.[doi:10.3969/j.issn.1006-1959.2023.07.026]
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保乳术联合前哨淋巴结活检治疗早期三阴性乳腺癌的临床疗效()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年07期
页码:
135-138
栏目:
论著
出版日期:
2023-04-01

文章信息/Info

Title:
Clinical Efficacy of Breast Conserving Surgery Combined with Sentinel Lymph Node Biopsy in the Treatment of Early Triple Negative Breast Cancer
文章编号:
1006-1959（2023）07-0135-04
作者:
万玉峰
（佳木斯市中心医院普外一科，黑龙江 佳木斯 154003）
Author(s):
WAN Yu-feng
(The First Department of General Surgery,Jiamusi Central Hospital,Jiamusi 154003,Heilongjiang,China)
关键词:
保乳术; 前哨淋巴结活检; 早期三阴性乳腺癌; 改良根治术
Keywords:
Breast conserving surgery; Sentinel lymph node biopsy; Early triple negative breast cancer; Modified radical mastectomy
分类号:
R736.3
DOI:
10.3969/j.issn.1006-1959.2023.07.026
文献标志码:
A
摘要:
目的 研究保乳术联合前哨淋巴结活检治疗早期三阴性乳腺癌的临床疗效。方法 选取2020年6月-2021年6月在我院诊治的54例早期三阴性乳腺癌患者为研究对象，采用随机数字表法分为对照组和观察组，各组27例。对照组采用改良根治术治疗，观察组采用保乳术联合前哨淋巴结活检治疗，比较两组临床疗效、手术指标、并发症发生率、生存质量、乳房美观满意度、复发率及生存率。结果 观察组治疗总有效率为92.59%，与对照组的96.30%比较，差异无统计学意义（P＞0.05）；观察组手术时间、术中出血量、住院时间均短于对照组（P＜0.05）；观察组并发症发生率低于对照组（P＜0.05）；观察组生存质量评分高于对照组（P＜0.05）；观察组乳房美观满意度为96.30%，高于对照组的77.78%（P＜0.05）；随访1年，观察组复发率（11.11%）、生存率（88.89%）与对照组（7.41%、92.59%）比较，差异无统计学意义（P＞0.05）。结论 保乳术联合前哨淋巴结活检治疗早期三阴性乳腺癌可实现与改良根治术相似的临床疗效，且可减少术中出血量、缩短手术和住院时间，降低并发症发生率，提高乳房美观满意度。同时对患者的局部复发和生存率无影响，具有良好的安全性，值得临床应用。
Abstract:
Objective To study the clinical efficacy of breast conserving surgery combined with sentinel lymph node biopsy in the treatment of early triple negative breast cancer.Methods A total of 54 patients with early triple negative breast cancer diagnosed and treated in our hospital from June 2020 to June 2021 were selected as the research objects. They were divided into control group and observation group by random number table method, with 27 cases in each group. The control group was treated with modified radical mastectomy, and the observation group was treated with breast conserving surgery combined with sentinel lymph node biopsy. The clinical efficacy, surgical indicators, complication rate, quality of life, breast aesthetic satisfaction, recurrence rate and survival rate were compared between the two groups.Results The total effective rate of treatment in the observation group was 92.59%, which was compared with 96.30% in the control group, the difference was not statistically significant (P>0.05). The operation time, intraoperative blood loss and hospitalization time of the observation group were shorter than those of the control group (P<0.05). The incidence of complications in the observation group was lower than that in the control group (P<0.05). The quality of life score of the observation group was higher than that of the control group (P<0.05). The breast aesthetic satisfaction of the observation group was 96.30%, which was higher than 77.78% of the control group (P<0.05). After 1 year of follow-up, there was no significant difference in recurrence rate and survival rate between the observation group (11.11%, 88.89%)and the control group (7.41%, 92.59%) (P>0.05).Conclusion Breast conserving surgery combined with sentinel lymph node biopsy in the treatment of early triple negative breast cancer can achieve similar clinical efficacy as modified radical mastectomy, and can reduce intraoperative blood loss, shorten operation and hospitalization time, reduce the incidence of complications, and improve breast aesthetic satisfaction. At the same time, it has no effect on the local recurrence and survival rate of patients. It has good safety and is worthy of clinical application.

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更新日期/Last Update: 1900-01-01