[1]黄 敏.内镜下黏膜切除术在胃肠道息肉患者中的有效性及安全性分析[J].医学信息,2024,37(17):105-108.[doi:10.3969/j.issn.1006-1959.2024.17.021]
　HUANG Min.Analysis of the Efficacy and Safety of Endoscopic Mucosal Resection in Patientswith Gastrointestinal Polyps[J].Journal of Medical Information,2024,37(17):105-108.[doi:10.3969/j.issn.1006-1959.2024.17.021]
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内镜下黏膜切除术在胃肠道息肉患者中的有效性及安全性分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
37卷
期数:
2024年17期
页码:
105-108
栏目:
论著
出版日期:
2024-09-01

文章信息/Info

Title:
Analysis of the Efficacy and Safety of Endoscopic Mucosal Resection in Patientswith Gastrointestinal Polyps
文章编号:
1006-1959（2024）17-0105-04
作者:
黄 敏
南城县人民医院消化内科，江西 南城 344799
Author(s):
HUANG Min
Department of Gastroenterology,Nancheng County People’s Hospital,Nancheng 344799,Jiangxi,China
关键词:
内镜下黏膜切除术; 胃肠道息肉; 胃肠道激素; 炎症因子
Keywords:
Endoscopic mucosal resection; Gastrointestinal polyps; Gastrointestinal hormones; Inflammatory factors
分类号:
R656.6
DOI:
10.3969/j.issn.1006-1959.2024.17.021
文献标志码:
A
摘要:
目的 研究内镜下黏膜切除术（EMR）对胃肠道息肉患者的治疗效果及安全性。方法 选取2023年1月-10月我院诊治的60例胃肠息肉患者为研究对象，采用随机数字表法分为对照组（n=30）和研究组（n=30）。对照组给予普通内镜电凝切除术，研究组给予EMR治疗，比较两组息肉切除情况、临床手术指标（息肉切除时间、手术时间、出血量、术后开始进流食时间、住院时间）、炎症因子水平[降钙素原（PCT）、白细胞介素-6（IL-6）、C反应蛋白（CRP）、白细胞介素-17（IL-17）]、胃肠道激素水平（胃动素、胃泌素）以及并发症发生率。结果 研究组息肉完整切除率为96.67%，高于对照组的80.00%（P＜0.05）；研究组息肉切除时间、手术时间、术后开始进流食时间均短于对照组，出血量少于对照组（P＜0.05），而两组住院时间比较，差异无统计学意义（P＞0.05）；两组术后PCT、IL-6、CRP、IL-17水平均高于术前，但研究组低于对照组（P＜0.05）；两组术后胃动素、胃泌素均低于术前，但研究组高于对照组（P＜0.05）；研究组并发症发生率为6.67%，低于对照组的16.67%（P＜0.05）。结论 EMR可提高胃肠道息肉患者息肉完整切除率，减小机体炎症应激、胃肠应激反应，缩短手术和息肉切除时间，减少术中出血量，降低并发症发生率，值得临床加以应用。
Abstract:
Objective To study the therapeutic effect and safety of endoscopic mucosal resection (EMR) in patients with gastrointestinal polyps.Methods A total of 60 patients with gastrointestinal polyps diagnosed and treated in our hospital from January to October 2023 were selected as the research objects. They were divided into control group(n=30) and study group (n=30) by random number table method. The control group was treated with ordinary endoscopic electrocoagulation, and the study group was treated with EMR. The polyp resection, clinical operation indexes (polyp resection time, operation time, bleeding volume, postoperative feeding time, hospitalization time), inflammatory factors levels[procalcitonin (PCT), interleukin-6 (IL-6), C-reactive protein (CRP), interleukin-17 (IL-17)] , gastrointestinal hormones levels (motilin, gastrin) and complication rate were compared between the two groups.Results The complete resection rate of polyps in the study group was 96.67%, which was higher than 80.00% in the control group (P<0.05). The polyp resection time, operation time and postoperative feeding time in the study group were shorter than those in the control group, and the amount of bleeding was less than that in the control group (P<0.05). There was no significant difference in hospitalization time between the two groups (P>0.05). The levels of PCT, IL-6, CRP and IL-17 in the two groups after operation were higher than those before operation, and those in the study group were lower than the control group (P<0.05). The levels of motilin and gastrin in the two groups were lower than those before operation, but those in the study group were higher than those in the control group (P<0.05). The incidence of complications in the study group was 6.67%, which was lower than 16.67% in the control group (P<0.05).Conclusion EMR can improve the complete resection rate of polyps in patients with gastrointestinal polyps, reduce the body’s inflammatory stress and gastrointestinal stress response, shorten the operation and polyp resection time, reduce intraoperative blood loss, and reduce the incidence of complications. It is worthy of clinical application.

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更新日期/Last Update: 1900-01-01