[1]李乐平,程华凤,张文芳.早期神经康复治疗对脑梗死急性期患者脑功能重塑及血清炎症因子水平的影响[J].医学信息,2025,38(18):78-82.[doi:10.3969/j.issn.1006-1959.2025.18.017]
　LI Leping,CHENG Huafeng,ZHANG Wenfang.Effect of Early Neurorehabilitation on Brain Function Remodeling and Serum Inflammatory Factorsin Patients with Acute Cerebral Infarction[J].Journal of Medical Information,2025,38(18):78-82.[doi:10.3969/j.issn.1006-1959.2025.18.017]
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早期神经康复治疗对脑梗死急性期患者脑功能重塑及血清炎症因子水平的影响()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
38卷
期数:
2025年18期
页码:
78-82
栏目:
论著
出版日期:
2025-09-15

文章信息/Info

Title:
Effect of Early Neurorehabilitation on Brain Function Remodeling and Serum Inflammatory Factorsin Patients with Acute Cerebral Infarction
文章编号:
1006-1959（2025）18-0078-05
作者:
李乐平1; 程华凤2; 张文芳3
1.上饶东信第五医院康复疼痛科，江西 上饶 334000；2.上饶市中心医院神经内科，江西 上饶 334000；3.上饶东信康复医院康复科，江西 上饶 334000
Author(s):
LI Leping1;  CHENG Huafeng2;  ZHANG Wenfang3
1.Department of Rehabilitation and Pain, Shangrao Dongxin Fifth Hospital, Shangrao 334000, Jiangxi, China;2.Department of Neurology, Shangrao Central Hospital, Shangrao 334000, Jiangxi, China;3.Department of Rehabilitation, Shangrao Dongxin Rehabilitation Hospital, Shangrao 334000, Jiangxi, China
关键词:
早期神经康复治疗; 脑梗死; 急性期; 脑功能重塑; 血清炎性因子
Keywords:
Early neurological rehabilitation;  Cerebral infarction;  Acute phase;  Brain function remodeling;  Serum inflammatory factors
分类号:
R493
DOI:
10.3969/j.issn.1006-1959.2025.18.017
文献标志码:
A
摘要:
目的 观察早期神经康复治疗对脑梗死急性期患者脑功能重塑及血清炎症因子水平的影响。方法 选取2021年1月-2024年1月上饶东信第五医院收治的60例脑梗死急性期患者作为研究对象，按照随机数字表法将其分为对照组和研究组，各30例。对照组采取常规药物进行治疗，研究组实施早期神经康复治疗。比较两组临床疗效、脑功能重塑能力（神经功能、认知功能、运动功能、日常生活活动能力）、生活质量（社会功能、情绪功能、躯体功能、总体健康）、血清炎症因子[超敏C-反应蛋白（hs-CRP）、白细胞介素-8（IL-8）、一氧化氮（NO）]。结果 研究组治疗总有效率（96.67%）高于对照组（73.33%）（P＜0.05）。两组治疗后NIHSS评分低于治疗前，MMSE、Fugl-Meyer、ADL评分高于治疗前，且研究组治疗后以上评分均优于对照组（P＜0.05）；两组治疗后生活质量各维度评分均高于治疗前，且研究组治疗后以上评分高于对照组（P＜0.05）；两组治疗后hs-CRP、IL-8、NO水平均低于治疗前，且研究组治疗后以上血清炎症因子水平均低于对照组（P＜0.05）。结论 早期神经康复治疗脑梗死急性期患者的效果确切，能够提高患者脑功能重塑能力及生活质量，减轻炎症反应，值得临床应用。
Abstract:
Objective To observe the effect of early neurorehabilitation on brain function remodeling and serum inflammatory factors in patients with acute cerebral infarction. Methods A total of 60 patients with acute cerebral infarction admitted to Shangrao Dongxin Fifth Hospital from January 2021 to January 2024 were selected as the research objects. According to the random number table method, they were divided into control group and study group, 30 patients per group. The control group was treated with conventional drugs, and the study group was treated with early neurological rehabilitation. The clinical efficacy, brain function remodeling ability (neurological function, cognitive function, motor function, activities of daily living), quality of life (social function, emotional function, physical function, overall health), serum inflammatory factors [high-sensitivity C-reactive protein (hs-CRP), interleukin-8 (IL-8), nitric oxide (NO)] were compared between the two groups. Results The study group (96.67%) had higher the total effective rate of treatment than that in the control group (73.33%) (P<0.05). After treatment, the NIHSS score of the two groups was lower than that before treatment, and the MMSE, Fugl-Meyer and ADL scores were higher than those before treatment, and the above scores of the study group were better than those of the control group (P<0.05). After treatment, the scores of each dimension of quality of life in the two groups were higher than those before treatment, and the above scores in the study group were higher than those in the control group (P<0.05). After treatment, the levels of hs-CRP, IL-8 and NO in the two groups were lower than those before treatment, and the levels of serum inflammatory factors in the study group were lower than those in the control group (P<0.05). Conclusion Early neurological rehabilitation is effective in the treatment of patients with acute cerebral infarction, which can improve the brain function remodeling ability and quality of life, and reduce the inflammatory response. It is worthy of clinical application.

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更新日期/Last Update: 1900-01-01