[1]李淑娟,王爱芹,杨学军,等.异常子宫出血患者子宫内膜病理类型与 临床特征的关系[J].医学信息,2019,32(14):104-106.[doi:10.3969/j.issn.1006-1959.2019.14.032]
 LI Shu-juan,WANG Ai-qin,YANG Xue-jun,et al.Relationship between Pathologic Type of Endometrium and Its Clinical Features in Patients with Abnormal Uterus Bleeding[J].Journal of Medical Information,2019,32(14):104-106.[doi:10.3969/j.issn.1006-1959.2019.14.032]
点击复制

异常子宫出血患者子宫内膜病理类型与 临床特征的关系()
分享到:

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年14期
页码:
104-106
栏目:
临床研究
出版日期:
2019-07-15

文章信息/Info

Title:
Relationship between Pathologic Type of Endometrium and Its Clinical Features in Patients with Abnormal Uterus Bleeding
文章编号:
1006-1959(2019)14-0104-03
作者:
李淑娟王爱芹杨学军常子强
北京市顺义区医院妇科,北京 101300
Author(s):
LI Shu-juanWANG Ai-qinYANG Xue-junCHANG Zi-qiang
Department of Gynecology,Shunyi District Hospital,Beijing 101300,China
关键词:
异常子宫出血子宫内膜病理肥胖代谢综合征
Keywords:
Key words:Abnormal uterus bleedingEndometrial pathologyObesityMetabolic syndrome
分类号:
R711
DOI:
10.3969/j.issn.1006-1959.2019.14.032
文献标志码:
A
摘要:
目的 探讨异常子宫出血患者子宫内膜病理类型与患者年龄、肥胖、高血压、血糖异常及高脂血症的关系。方法 收集2018年1月1日~12月31日在我院因异常子宫出血进行宫腔镜手术和诊刮的符合条件的277例患者的临床资料,包括子宫内膜病理结果、年龄、身高、体质量、血糖、血脂、血压等,计算异常子宫出血患者中子宫内膜病理类型的构成比,分析不同病理结果与患者年龄、肥胖、血压、血糖及血脂的关系。结果 ①子宫内膜病理类型包括正常子宫内膜、子宫内膜息肉、子宫内膜增生不伴非典型性、子宫内膜增生伴非典型性及子宫内膜癌的构成比分别为23.10%、25.27%、42.24%、6.49%和2.88%;②子宫内膜癌患者平均年龄(54.87±3.35)岁,大于正常子宫内膜患者的平均年龄(36.29±3.27)岁,统计学意义显著(P<0.01);③子宫内膜增生伴非典型性患者及子宫内膜癌患者肥胖的高血压、血糖异常及高血脂发生情况与正常子宫内膜患者比较,差异有统计学意义(P<0.05)。结论 异常子宫出血患者近一半人群存在子宫内膜增生,个别患者甚至出现癌变,与肥胖、高血压、高血脂及血糖异常有一定联系,提示子宫内膜病变可能与代谢性疾病相关。建议患者尽早改变生活方式,合理饮食及运动以改善机体的代谢,则有可能在很大程度上预防子宫内膜癌的发生。
Abstract:
Abstract:Objective To investigate the relationship between endometrial pathological types of patients with abnormal uterus bleeding and age, obesity, hypertension, abnormal blood glucose and hyperlipidemia. Methods The clinical data of 277 patients who underwent hysteroscopic surgery and diagnosis of uterus bleeding due to abnormal uterus bleeding from January 1 to December 31, 2018, including endometrial pathological results, age, height, body mass, blood glucose, blood lipids, blood pressure, etc., to calculate the composition ratio of endometrial pathological types in patients with abnormal uterus bleeding, and to analyze the relationship between different pathological results and factors such as age, obesity, blood pressure, blood sugar and blood lipids. Results ○1Endometrial pathological types including normal endometrium, endometrial polyps, endometrial hyperplasia without atypical, endometrial hyperplasia with atypical and endometrial cancer, the composition ratio was respectively 23.10%, 25.27 %, 42.24%, 6.49%, and 2.88%; ○2Me age of endometrial cancer patients (54.87±3.35) years old, greater than the average age of normal endometrial patients (36.29±3.27) years, with stically significant (P<0.01); ○3Eometrial hyperplasia with atypical patients, endometrial cancer patients with obesity, hypertension, abnormal blood glucose and high blood lipids compared with normal endometrial patients, the difference was statistically significant (P<0.05).Conclusion Endometrial hyperplasia exists in nearly half of patients with abnormal uterus bleeding. Individual patients may even develop cancer, which is associated with obesity, hypertension, hyperlipidemia and abnormal blood glucose, suggesting that endometrial lesions may be associated with metabolic diseases. It is recommended that patients change their lifestyle as early as possible, and proper diet and exercise to improve the body's metabolism may prevent endometrial cancer to a large extent.

参考文献/References:

[1]中华医学会妇产科分会妇科内分泌学组.异常子宫出血诊断与治疗指南[J].中华妇产科杂志,2014,49(11):801-806. [2]Kurman RJ,Ellenson LH,Ronnett BM.Blaustein′s pathology of the female genital tract[M].New York:Springer,2011:514. [3]中华医学会内分泌学分会肥胖学组.中国成人肥胖症防治专家共识[J].中华内分泌代谢杂志,2011,27(9):711-717. [4]中国成人血脂异常防治指南制订联合委员会.中国成人血脂异常防治指南[J].中华心血管病杂志,2007,35(5):390-419. [5]中华医学会糖尿病学分会.中国2型糖尿病防治指南(2013年版)[J].中华内分泌代谢杂志,2014,30(10):893-942. [6]张宇,成娟,叶青剑,等.异常子宫出血的子宫内膜病理特点及与肥胖的关系[J].中山大学学报(医学科学版),2019,40(2):316-320. [7]Goivanninil L,Tirabassig G,Muscogiurig G,et al.Impact of adult growth hormone deficiency on meta bolic profile and cardiovascular risk[J].Endocr J,2015,62(12):1037-1048. [8]Wise MR,Gill P,Lensen S,et al.Body mass index trumps age in decisionfor endometrial biopsy:cohort study of symptomatic premenopausal women[J].Am J Obstet Gynecol,2016,215(5):591-598. [9]Sanderson PA,Critchley HO,Williams AR,et al.Newconcepts for an old problem:the diagnosis of endometrial hyperplasia[J].Hum Reprod Update,2017,23(2):232-254. [10]Committee on Gynecologic Practice,Society of Gynecologic Oncology.The American College of Obstetricians and Gynecologists Committee opinion no.631.Endometrial intraepithelial neoplasia[J].Obstet Gynecol,2015,125(5):1272-1278. [11]Lai Y,Sun C.Association of abnormal glucose metabolism and insulin resistance in patients with atypical and typical endometrial cancer[J].Oncol Lett,2018,15(2):2173-2178. [12]Keimoglu OS,Pekin A,Yilmaz SA,et al.Effect of the percentage of body fat on surgical,clinical and pathological outcomes in women with endometrial cancer[J].J Obstet Gynaecol Res,2015,41(3):449-455.

相似文献/References:

[1]汤小燕.亮丙瑞林联合曼月乐环对异常子宫出血患者出血量及性激素水平的影响[J].医学信息,2023,36(19):152.[doi:10.3969/j.issn.1006-1959.2023.19.034]
 TANG Xiao-yan.Effect of Leuprorelin Combined with Mirena on Amount of Bleeding and Sex Hormone Levels in Patients with Abnormal Uterine Bleeding[J].Journal of Medical Information,2023,36(14):152.[doi:10.3969/j.issn.1006-1959.2023.19.034]
[2]邵景萍.曼月乐与地屈孕酮治疗围绝经期异常子宫出血的疗效及对性激素水平的影响[J].医学信息,2022,35(07):165.[doi:10.3969/j.issn.1006-1959.2022.07.043]
 SHAO Jing-ping.Efficacy of Mirena and Dydrogesterone in the Treatment of Perimenopausal Abnormal Uterine Bleeding and its Effect on Sex Hormone Levels[J].Journal of Medical Information,2022,35(14):165.[doi:10.3969/j.issn.1006-1959.2022.07.043]
[3]李建一.奥美拉唑与兰索拉唑治疗成人活动期胃溃疡的临床疗效及对溃疡愈合的影响[J].医学信息,2022,35(08):156.[doi:10.3969/j.issn.1006-1959.2022.08.040]
 LI Jian-yi.Clinical Efficacy of Omeprazole and Lansoprazole in the Treatment of Active Gastric Ulcer in Adults and its Effect on Ulcer Healing[J].Journal of Medical Information,2022,35(14):156.[doi:10.3969/j.issn.1006-1959.2022.08.040]

更新日期/Last Update: 2019-07-15