[1]刘永刚,张学勇.醒脑静联合盐酸纳洛酮治疗脑出血后昏迷患者的疗效分析[J].医学信息,2019,32(06):157-158.[doi:10.3969/j.issn.1006-1959.2019.06.050]
　LIU Yong-gang,ZHANG Xue-yong.Therapeutic Effect of Xingnaojing Combined with Naloxone Hydrochloride on Patients with Coma after Cerebral Hemorrhage[J].Journal of Medical Information,2019,32(06):157-158.[doi:10.3969/j.issn.1006-1959.2019.06.050]
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醒脑静联合盐酸纳洛酮治疗脑出血后昏迷患者的疗效分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年06期
页码:
157-158
栏目:
药物与临床
出版日期:
2019-03-15

文章信息/Info

Title:
Therapeutic Effect of Xingnaojing Combined with Naloxone Hydrochloride on Patients with Coma after Cerebral Hemorrhage
文章编号:
1006-1959（2019）06-0157-03
作者:
刘永刚1; 张学勇2
（1.佳木斯大学附属第一医院神内三科，黑龙江 佳木斯 154000；2.解放军联勤保障部队第963医院内一科，黑龙江 佳木斯 154000）
Author(s):
LIU Yong-gang1; ZHANG Xue-yong2
(1.Department of Neurology,Subject three,the First Affiliated Hospital of Jiamusi University,Jiamusi 154000,Heilongjiang,China;2.Department of Internal Medicine,Subject One,the 963th Hospital of the Joint Service of the People's Liberation Army,Jiamusi 15
关键词:
醒脑静; 盐酸纳洛酮; 脑出血后昏迷
Keywords:
Xingnaojing; Naloxone hydrochloride; Coma after cerebral hemorrhage
分类号:
R743.34
DOI:
10.3969/j.issn.1006-1959.2019.06.050
文献标志码:
A
摘要:
目的 分析醒脑静联合盐酸纳洛酮治疗脑出血后昏迷患者治疗效果。方法 选取我院2015年1月~2017年10月中收治脑出血后昏迷患者68例作为研究对象，随机分为参照组和联合组，每组34例。参照组在常规治疗上加盐酸纳洛酮，联合组在参照组的基础上加用醒脑静配合治疗，将两组GCS分值与脑血肿量变化及NIHSS评分情况进行比较。结果 治疗后联合组的GCS分值（14.24±2.05）分与脑血肿量（17.41±2.44）ml明显优于参照组的（9.87±1.62）分和（25.50±2.42）ml，差异有统计学意义（P＜0.05）；联合组在出院后3个月的NIHSS评分情况（10.01±1.95）分优于参照组（12.50±2.31）分，差异有统计学意义（P＜0.05）。结论 采用醒脑静联合盐酸纳洛酮治疗脑出血后昏迷患者可显著改善脑出血患者的意识障碍,促进神经功能恢复,减轻脑部水肿情况,改善患者临床疗效。
Abstract:
Objective To analyze the therapeutic effect of Xingnaojing combined with naloxone hydrochloride in the treatment of coma patients with cerebral hemorrhage. Methods A total of 68 patients with coma after cerebral hemorrhage were enrolled in our hospital from January 2015 to October 2017. They were randomly divided into reference group and combined group, with 34 cases in each group. In the reference group, naloxone hydrochloride was added to the conventional treatment, and the combined group was treated with Xingnaojing on the basis of the reference group. The GCS scores of the two groups were compared with the changes of cerebral hematoma volume and NIHSS score. Results After treatment, the GCS score (14.24±2.05) and cerebral hematoma volume (17.41±2.44) ml were significantly better than the reference group (9.87±1.62) and (25.50±2.42) ml,the difference was statistically significant (P<0.05); The NIHSS score (10.01±1.95) in the combined group was better than the reference group (12.50±2.31) at 3 months after discharge,the difference was statistically significant (P<0.05). Conclusion The treatment of coma after cerebral hemorrhage with Xingnaojing combined with naloxone hydrochloride can significantly improve the disturbance of consciousness in patients with cerebral hemorrhage, promote the recovery of nerve function, reduce the edema of the brain and improve the clinical efficacy of patients.

参考文献/References:

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更新日期/Last Update: 2019-03-15