[1]何高琴,游茂林.2010~2018年重庆市梁平区手足口病流行病学及病原学特征分析[J].医学信息,2020,33(09):131-133.[doi:10.3969/j.issn.1006-1959.2020.09.041]
　HE Gao-qin,YOU Mao-lin.Epidemiology and Pathogenic Characteristics of Hand-foot-mouth Disease in Liangping District,Chongqing,2010~2018[J].Medical Information,2020,33(09):131-133.[doi:10.3969/j.issn.1006-1959.2020.09.041]
点击复制

2010~2018年重庆市梁平区手足口病流行病学及病原学特征分析()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年09期
页码:
131-133
栏目:
调查分析
出版日期:
2020-05-01

文章信息/Info

Title:
Epidemiology and Pathogenic Characteristics of Hand-foot-mouth Disease in Liangping District,Chongqing,2010~2018
文章编号:
1006-1959（2020）09-0131-03
作者:
何高琴; 游茂林
（重庆市梁平区疾病预防控制中心，重庆 400155）
Author(s):
HE Gao-qin; YOU Mao-lin
(Chongqing Liangping District Center for Disease Control and Prevention,Chongqing 400155,China)
关键词:
手足口病; 流行特征; 防控策略
Keywords:
Hand-foot-mouth disease; Epidemic characteristics; Prevention and control strategies
分类号:
R725.1
DOI:
10.3969/j.issn.1006-1959.2020.09.041
文献标志码:
A
摘要:
目的 了解重庆梁平区2010~2018年手足口病流行规律，制定科学的防控策略。方法 对2010~2018年重庆市梁平区法定传染病疫情报告系统报告梁平区手足口病10255例进行整理、分析。结果 2010~2018年梁平区累计报告手足口病10255例，年均发病率161.32/10万；总体呈隔年高发和波动上升的趋势；具有明显的季节性，3~5月份和10~12月份为发病高峰；各乡镇报告发病率存在明显差异，其中城区及城郊发病率较高，山区发病率较低；男童发病率高于女童（P＜0.05）；病例以5岁以下婴幼儿为主，人群分布集中在散居儿童，共6722例，占病例总数的65.55%，其次为幼托儿童，发病3319例，占病例总数的32.36%；手足口病病例发病3 d内就诊构成总体上逐年增多，就诊及时性逐年提高；手足口病病毒优势毒株不断变化，EV71是重症及死亡病例的危险病原型，同时5~7月份和11月份是手足口病重症和死亡病例的高风险时期。结论 手足口病的防制应坚持预防为主，采取宣传教育、防治结合、群防群控的综合防控策略。做好疫情监测和风险评估工作，开展不同人群不同地区针对性的宣传教育，联合教育部门做好托幼机构、学校等重点场所手足口病日常防护的指导，以及聚集性/暴发疫情发现、应对和处置准备,积极推进EV-A71疫苗接种等各项综合防控工作，有效降低手足口病的发病率及病死率。
Abstract:
Objective To understand the prevalence of hand-foot-mouth disease in Liangping District of Chongqing from 2010 to 2018, and to formulate scientific prevention and control strategies.Methods From 2010 to 2018, 10255 cases of hand-foot-mouth disease in Liangping District were reported and analyzed in the report system of legal infectious diseases in Liangping District, Chongqing.Results From 2010 to 2018, a total of 10,255 cases of hand-foot-mouth disease were reported in Liangping District, with an average annual incidence of 161.32 per 100,000; the overall trend is high and fluctuating every other year; it has obvious seasonality, from March to May and October to December Peak incidence; There are significant differences in reported incidence among towns and villages, among which urban and suburban areas have higher incidences and mountainous areas have lower incidences; boys have higher incidences than girls (P<0.05); cases are mainly infants and children under 5 years of age. The population distribution was concentrated in scattered children, a total of 6,722 cases, accounting for 65.55% of the total number of cases, followed by child care children, with 3,319 cases, accounting for 32.36% of the total number of cases;Hand-foot-mouth disease cases within 3 d of onset of visits generally increased year by year, and the timeliness of visits increased year by year; the dominant strains of hand-foot-mouth disease virus kept changing. EV71 is a dangerous disease prototype of severe and dead cases, and from May to July and November is a high-risk period for severe hand-foot-mouth disease and deaths.Conclusion The prevention and control of hand-foot-mouth disease should insist on prevention, and adopt a comprehensive prevention and control strategy of publicity and education, combination of prevention and control, and group prevention and control.Do a good job in epidemic monitoring and risk assessment, carry out targeted publicity and education for different groups of people in different areas, and joint education departments should provide guidance on day-to-day prevention of hand-foot-mouth disease in key places such as child care institutions and schools, as well as cluste /outbreak outbreak detection and response and preparation for treatment, and actively promote the EV-A71 vaccination and other comprehensive prevention and control work, effectively reduce the incidence of hand-foot-mouth disease and mortality.

参考文献/References:

[1]李兰娟,任红.传染病学[M].北京:人民卫生出版社,2013:125.[2]刘宏灵,刘莹莹,于秋丽,等.2011-2014年河北省手足口病流行特征及病原特征分析[J].现代预防医学,2016,43(13):2315-2319.[3]中华人民共和国国家卫生和计划生育委员会.手足口病预防控制指南(2009年版)[J].全科医学临床与教育,2012,19(19):125-127.[4]张珺茹,蔡源益,王爱,等.2014年至2016年全国手足口病发病季节高峰的圆形分布分析[J].中国医科大学学报,2017,46(6):524-526,531. [5]邹晓妮,张小庄,王波,等.广州市5757例手足口病肠道病毒与气候因素的相关性[J].中国热带医学,2012,12(7):815-817,820.[6]陈少伟,孙忠.天津市西青区2011-2015年手足口病流行病学特征及病原监测分析[J].中国卫生统计,2018,2(35):119-121.[7]彭瑞吟,甘露,彭清琴,等.2010-2014年深圳市宝安区手足口病流行特征研究[J].现代预防医学,2016,43(8):1377-1380.[8]林虹,马江涛,陈慧,等.宁夏回族自治区2013-2014年手足口病病原学分析[J].中国公共卫生,2015,31(11):1489-1492.[9]但蓓蓓.新生儿手足口病一例[J].临床误诊误治,2016,29(6):23.[10]陈熙,李勤.重庆市 2010-2012年手足口病病原流行特征分析[J]．中国热带医学,2015,10(15):1418-1422.

相似文献/References:

[1]覃 艺,邓燕艺,赖昌生,等.手足口病患儿体内免疫球蛋白、补体、C反应蛋白及刺激分析CD80、CD86水平的临床意义及其与丙种球蛋白治疗疗效的关系[J].医学信息,2018,31(02):63.[doi:10.3969/j.issn.1006-1959.2018.02.022]
　Qin Yi,DENG Yan-yi,LAI Chang-sheng,et al.Clinical Significance of Immunoglobulin,Complement,C-reactive Protein and CD80,CD86 in Children with Hand-foot-mouth Disease and their Relationship with Therapeutic Effect of Gamma Globulin[J].Medical Information,2018,31(09):63.[doi:10.3969/j.issn.1006-1959.2018.02.022]
[2]李 淼,孙浩淼,纵书芳,等.徐州地区2015~2016年手足口病流行病学特征分析[J].医学信息,2018,31(02):77.[doi:10.3969/j.issn.1006-1959.2018.02.026]
　LI Miao,SUN Hao-miao,ZONG Shu-fang,et al.Epidemiological Characteristics of Hand-foot-mouth Disease in Xuzhou Area in 2015 to 2016[J].Medical Information,2018,31(09):77.[doi:10.3969/j.issn.1006-1959.2018.02.026]
[3]任燕.手足口病患儿血清淋巴细胞免疫分型的水平变化及临床意义[J].医学信息,2018,31(01):82.[doi:10.3969/j.issn.1006-1959.2018.01.029]
　REN Yan.Serum Level of Lymphocyte Immunophenotype in Children with Hand-foot-mouth Disease and its Clinical Significance[J].Medical Information,2018,31(09):82.[doi:10.3969/j.issn.1006-1959.2018.01.029]
[4]吴华.人感染H7N9禽流感病毒的流行特征分析[J].医学信息,2018,31(01):125.[doi:10.3969/j.issn.1006-1959.2018.01.048]
　WU Hua.Analysis of the Epidemic Characteristics of Human Infected H7N9 Avian Influenza Virus[J].Medical Information,2018,31(09):125.[doi:10.3969/j.issn.1006-1959.2018.01.048]
[5]覃 艺,邓燕艺,赖昌生,等.554例儿童重症手足口病的临床特征分析[J].医学信息,2018,31(11):115.[doi:10.3969/j.issn.1006-1959.2018.11.036]
　QIN Yi,DENG Yan-yi,LAI Chang-sheng,et al.Analysis of Clinical Features of Severe Hand Foot and Mouth Disease in 554 Children[J].Medical Information,2018,31(09):115.[doi:10.3969/j.issn.1006-1959.2018.11.036]
[6]兰文林,白宝鑫,石武祥.手足口病研究进展及防治措施[J].医学信息,2018,31(15):29.[doi:10.3969/j.issn.1006-1959.2018.15.011]
　LAN Wen-lin,BAO Bao-xin,SHI Wu-xiang.Research Progress and Control Measures of Hand-Foot-Mouth Disease[J].Medical Information,2018,31(09):29.[doi:10.3969/j.issn.1006-1959.2018.15.011]
[7]刘 娜,闫卫利.2016年我院儿童病院肠道病毒71型感染情况调查[J].医学信息,2018,31(15):115.[doi:10.3969/j.issn.1006-1959.2018.15.036]
　LIU Na,YAN Wei-li.Investigation of Human Enterovirus 71 Infection in our Children's Hospital in 2016[J].Medical Information,2018,31(09):115.[doi:10.3969/j.issn.1006-1959.2018.15.036]
[8]管 建,姜娟娟.血清IL-6、IL-10、CRP和PCT水平检测对手足口病早期 合并细菌感染患儿的临床诊断价值[J].医学信息,2018,31(15):146.[doi:10.3969/j.issn.1006-1959.2018.15.047]
　GUAN Jian,JIANG Juan-juan.Clinical Diagnostic Value of Serum Levels of IL-6,IL-10,CRP and PCT in Children with Hand-Foot-and-Mouth Disease Combined with Early Bacterial Infection[J].Medical Information,2018,31(09):146.[doi:10.3969/j.issn.1006-1959.2018.15.047]
[9]金常俭.2015~2017年辽阳市文圣区法定传染病流行特征分析[J].医学信息,2019,32(05):130.[doi:10.3969/j.issn.1006-1959.2019.05.041]
　JIN Chang-jian.Epidemiological Characteristics of Legal Infectious Diseases in Wensheng District of Liaoyang City from 2015 to 2017[J].Medical Information,2019,32(09):130.[doi:10.3969/j.issn.1006-1959.2019.05.041]
[10]李正兰.重组人干扰素α1b治疗小儿手足口病的临床疗效观察[J].医学信息,2019,32(05):156.[doi:10.3969/j.issn.1006-1959.2019.05.050]
　LI Zheng-lan.Clinical Observation of Recombinant Human Interferon α1b in the Treatment of Hand-Foot-Mouth Disease in Children[J].Medical Information,2019,32(09):156.[doi:10.3969/j.issn.1006-1959.2019.05.050]
[11]陆志刚,梁 洁,钟 敏.新疆第八师石河子市2015~2018年手足口病原学特征及病流行病学分析[J].医学信息,2019,32(06):82.[doi:10.3969/j.issn.1006-1959.2019.06.026]
　LU Zhi-gang,LIANG Jie,ZHONG Min.Epidemiological Characteristics and Epidemiological Analysis of Hand,Foot and Mouth in Shihezi City,the Eighth Division of Xinjiang from 2015 to 2018[J].Medical Information,2019,32(09):82.[doi:10.3969/j.issn.1006-1959.2019.06.026]

更新日期/Last Update: 2020-05-01