[1]陈玉峰,汪 虹,林晓莹,等.烧伤后糖代谢与免疫反应的关系[J].医学信息,2020,33(10):45-47.[doi:10.3969/j.issn.1006-1959.2020.10.013]
 CHEN Yu-feng,WANG Hong,LIN Xiao-ying,et al.Relationship Between Glucose Metabolism and Immune Response After Burn[J].Medical Information,2020,33(10):45-47.[doi:10.3969/j.issn.1006-1959.2020.10.013]
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烧伤后糖代谢与免疫反应的关系()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年10期
页码:
45-47
栏目:
综述
出版日期:
2020-05-15

文章信息/Info

Title:
Relationship Between Glucose Metabolism and Immune Response After Burn
文章编号:
1006-1959(2020)10-0045-03
作者:
陈玉峰汪 虹林晓莹
(昆明医科大学第二附属医院烧伤外科,云南 昆明 650101)
Author(s):
CHEN Yu-fengWANG HongLIN Xiao-yinget al
(Department of Burns,the Second Affiliated Hospital of Kunming Medical University,Kunming650101,Yunnan,China)
关键词:
烧伤糖代谢免疫调节性T细胞辅助性T细胞17
Keywords:
BurnsGlucose metabolismImmunityRegulatory T cellsHelper T cells 17
分类号:
R644
DOI:
10.3969/j.issn.1006-1959.2020.10.013
文献标志码:
A
摘要:
严重烧伤引起的糖代谢、炎症反应及免疫调节的失衡尤为显著,近年研究证实它们相互影响,发病机制存在明显的关联性。烧伤后应激性高血糖会影响免疫细胞及其细胞因子相关的炎症及免疫反应,而炎症介质可引起不同程度的胰岛素抵抗,炎症因子的释放增多可干扰胰岛素介导的葡萄糖摄取和利用从而导致血糖升高。本文就烧伤后糖代谢、免疫细胞(调节性T细胞及辅助性T细胞17)水平和功能、炎症反应的变化以及它们的相互作用关系展开综述。
Abstract:
The imbalance of sugar metabolism, inflammation and immune regulation caused by severe burns is particularly significant. In recent years, studies have confirmed that they affect each other, and there is a clear correlation between pathogenesis. Stress hyperglycemia after burns will affect the immune cells and their cytokines-related inflammation and immune response, and inflammatory mediators can cause varying degrees of insulin resistance, increased release of inflammatory factors can interfere with insulin-mediated glucose uptake and utilization resulting in Increased blood sugar. This article reviews the changes in glucose metabolism, immune cells(regulatory T cells and helper T cells 17)levels and functions, inflammation, and their interactions after burns.

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更新日期/Last Update: 2020-05-15