[1]王春远,刘成桂.成都市健康体检儿童25羟基维生素D水平分析[J].医学信息,2020,33(15):133-135.[doi:10.3969/j.issn.1006-1959.2020.15.041]
 WANG Chun-yuan,LIU Cheng-gui.Analysis on the Level of 25-hydroxy Vitamin D in Children UndergoingPhysical Examination in Chengdu[J].Medical Information,2020,33(15):133-135.[doi:10.3969/j.issn.1006-1959.2020.15.041]
点击复制

成都市健康体检儿童25羟基维生素D水平分析()
分享到:

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年15期
页码:
133-135
栏目:
调查分析
出版日期:
2020-08-01

文章信息/Info

Title:
Analysis on the Level of 25-hydroxy Vitamin D in Children UndergoingPhysical Examination in Chengdu
文章编号:
1006-1959(2020)15-0133-03
作者:
王春远刘成桂
电子科技大学医学院附属妇女儿童医院/成都市妇女儿童中心医院检验科,四川 成都 610091
Author(s):
WANG Chun-yuanLIU Cheng-gui
Women and Children’s Hospital Affiliated to School of Medicine,University of Electronic Science and Technology of China/Department of Laboratory Medicine,Chengdu Women and Children’s Central Hospital,Chengdu 610091,Sichuan,China
关键词:
25羟基维生素D化学发光法维生素缺乏维生素不足
Keywords:
25-hydroxy vitamin DChemiluminescence methodVitamin deficiencyVitamin deficiency
分类号:
R153.2
DOI:
10.3969/j.issn.1006-1959.2020.15.041
文献标志码:
A
摘要:
目的 了解成都市某三甲医院健康体检儿童维生素D状况,为临床合理补充维生素D提供理论依据。方法 回顾性分析2016年12月1日~2019年2月29日在成都市妇女儿童中心医院体检并进行常规血清25羟基维生素D检测的儿童,采用ADVIA centaur XP 全自动化学发光免疫分析仪以化学发光方法分析不同年龄、性别及季节健康体检儿童的血清25羟基维生素D水平。结果 ①儿童血清25羟基维生素D水平为(60.83±24.30)nmol/L,女性儿童25羟基维生素D水平为(59.35±23.24)nmol/L,男性儿童25羟基维生素D水平为(61.70±24.87)nmol/L,其中18.44%的儿童存在25羟基维生素D缺乏,16.91%的儿童存在25羟基维生素D不足,64.66%的儿童25羟基维生素D处于正常水平。②不同年龄儿童的25羟基维生素D缺乏率随着年龄的增加而增加,<1岁龄儿童25羟基维生素D缺乏率最低,>6岁儿童25羟基维生素D缺乏率最高,差异有统计学意义(P<0.05)。③不同季节儿童25羟基维生素D缺乏率不同,其中冬季最高,其次为春季和秋季,夏季最低,差异有统计学意义(P<0.05)。结论 成都市儿童25羟基维生素D存在不同程度的缺乏,且存在年龄季节和性别差异。建议相关部门定期监测儿童25羟基维生素D水平,合理补充维生素D,促进儿童健康发育。
Abstract:
Objective To understand the vitamin D status of children in a health checkup in a tertiary hospital in Chengdu, and provide a theoretical basis for clinically reasonable vitamin D supplementation.Methods A retrospective analysis of children who had a physical examination and routine serum 25-hydroxy vitamin D test at Chengdu Women’s and Children’s Central Hospital from December 1, 2016 to February 29, 2019 was performed using the ADVIA centaur XP automatic chemiluminescence immunoassay analyzer for chemical analysis. Luminescence method was used to analyze the serum 25-hydroxy vitamin D levels of children of different ages, genders and seasons during physical examination.Results ①The level of 25-hydroxy vitamin D in children’s serum is (60.83±24.30) nmol/L, the level of 25-hydroxyvitamin D in female children is (59.35±23.24) nmol/L, and the level of 25-hydroxy vitamin D in male children is (61.70±24.87) nmol/L among them, 18.44% of children had 25-hydroxy vitamin D deficiency, 16.91% of children had 25-hydroxy vitamin D deficiency, and 64.66% of children had 25-hydroxy vitamin D at a normal level.②The 25-hydroxy vitamin D deficiency rate of children of different ages increases with age. The 25-hydroxy vitamin D deficiency rate of children <1 year old was the lowest, and the 25-hydroxy vitamin D deficiency rate of children> 6 years old is the highest, the difference was statistically significant (P<0.05).③The 25-hydroxy vitamin D deficiency rates of children in different seasons were different, with the highest in winter, followed by spring and autumn, and the lowest in summer, the difference was statistically significant (P<0.05).Conclusion There are varying degrees of deficiency of 25-hydroxy vitamin D in children in Chengdu, and there are differences in age, season and gender. It is recommended that relevant departments regularly monitor children’s 25-hydroxy vitamin D levels, and reasonably supplement vitamin D to promote healthy development of children.

参考文献/References:

[1]McCollum EV,Simmonds N,Becker JE,et al.An experimental demonstration of the existence of a vitamin which promotes calcium deposition[J].J Biol Chen,1922,53(1):293-298.[2]Goltz Man D.Function of vitamin D in bone[J].Histochem Cell Biol,2018,149(4):305-312. [3]Haimi M,Kremer R.Vitamin D deficiency/insufficiency from childhood to adulthood: insights from a sunny country[J].World J Clin Pediatr,2017,6(1):1-9.[4]Wang L,Wang H,Wen H,et al.Relationship between HOMAIR and serum vitamin D in Chinese children and adolescents[J].J Pediatr Endocrinol Metab,2016,29(7):777-781.[5]Ekbom K,Marcus C.Vitamin D deficiency is associated with prediabetes in obese Swedish children [J].Acta Paediatr,2016,105(10):1192-1197.[6]李秋实,仰曙芬.维生素D缺乏与儿童代谢综合症的研究进展[J].中国儿童保健杂志,2016,24(4):381-383.[7]乔阳,王颖,白增华,等.血清25-羟维生素D水平对儿童免疫功能的影响[J].中国优生与遗传杂志,2014,22(9):165-166.[8]仰曙芬,吴光驰.维生素D缺乏及维生素D缺乏性佝偻病防治建议解读[J].中国儿童保健杂志,2015,23(7):680-683.[9]章建伟,王卓英.0-9岁儿童维生素D水平的调查[J].浙江预防医学,2015,27(3):229-231. [10]吴光驰.维生素D缺乏离我们有多远[J].中国妇幼卫生杂志,2014,5(3):72-75.[11]朱庆龄,陈俊伟,林卫华,等.泉州地区0~12岁儿童25羟维生素D水平分析[J].中华实用儿科临床杂志,2018,33(11):842-845.[12]邵小飞,郑娟,刘杰.1309例 0-7岁儿童25-羟基维生素D水平分析[J].中国妇幼卫生杂志,2015,6(3):26-29.[13]夏黎,崔县伟,王玉,等.南京地区0-5岁儿童25-羟基维生素D水平及其与季节的关系[J].中华实用儿科临床杂志,2015,30(19):1470-1472.[14]邓红岩,蔡婧晔,侯江婷,等.张家港市2942例婴幼儿25-羟基维生素D水平现状分析[J].现代预防医学,2018,45(16):2954-2957.[15]孔锐,宋媛,叶侃,等.苏州市0-6岁儿童骨密度调查及其与25羟基维生素D关系研究[J].中国骨质疏松杂志,2018,24(9):1219-1224.

相似文献/References:

[1]唐细田,肖 琳,徐彤慧.化学发光法和酶联免疫法在乙型肝炎病毒血清学检验中的效果比较[J].医学信息,2019,32(22):164.[doi:10.3969/j.issn.1006-1959.2019.22.057]
 TANG Xi-tian,XIAO Lin,XU Tong-hui.Comparison of the Effects of Chemiluminescence and Enzyme-linked Immunosorbent Assay on Serological Test of Hepatitis B Virus[J].Medical Information,2019,32(15):164.[doi:10.3969/j.issn.1006-1959.2019.22.057]
[2]杨培培,李 秀.血清25(OH)D水平对慢性阻塞性肺疾病急性加重的诊断价值[J].医学信息,2021,34(03):63.[doi:10.3969/j.issn.1006-1959.2021.03.019]
 YANG Pei-pei,LI Xiu.The Diagnostic Value of Serum 25(OH)D Level in Acute Exacerbation of Chronic Obstructive Pulmonary Disease[J].Medical Information,2021,34(15):63.[doi:10.3969/j.issn.1006-1959.2021.03.019]
[3]姜红峰,彭绍蓉,郭张强,等.低25(OH)D与老年2型糖尿病患者靶器官损害的关系[J].医学信息,2021,34(09):84.[doi:10.3969/j.issn.1006-1959.2021.09.022]
 JIANG Hong-feng,PENG Shao-rong,GUO Zhang-qiang,et al.The Relationship Between Low 25(OH)D and Target Organ Damage in Elderly Patients with Type 2 Diabetes[J].Medical Information,2021,34(15):84.[doi:10.3969/j.issn.1006-1959.2021.09.022]

更新日期/Last Update: 1900-01-01