[1]陆 皓,陈海琳,鲍计章,等.免疫抑制性细胞在免疫性血小板减少症中的作用[J].医学信息,2021,34(13):23-27,32.[doi:10.3969/j.issn.1006-1959.2021.13.007]
 LU Hao,CHEN Hai-lin,BAO Ji-zhang,et al.The Role of Immunosuppressive Cells in Immune Thrombocytopenia[J].Medical Information,2021,34(13):23-27,32.[doi:10.3969/j.issn.1006-1959.2021.13.007]
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免疫抑制性细胞在免疫性血小板减少症中的作用()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年13期
页码:
23-27,32
栏目:
综述
出版日期:
2021-07-01

文章信息/Info

Title:
The Role of Immunosuppressive Cells in Immune Thrombocytopenia
文章编号:
1006-1959(2021)13-0023-06
作者:
陆 皓陈海琳鲍计章
(上海中医药大学附属岳阳中西医结合医院血液科,上海 200437)
Author(s):
LU HaoCHEN Hai-linBAO Ji-zhanget al.
(Department of Hematology,Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine,Shanghai 200437,China)
关键词:
免疫性血小板减少症免疫抑制性细胞淋巴细胞循环血小板
Keywords:
Immune thrombocytopeniaImmunosuppressive cellsLymphocytesCirculating platelets
分类号:
R558+.2
DOI:
10.3969/j.issn.1006-1959.2021.13.007
文献标志码:
A
摘要:
免疫性血小板减少症(ITP)是一种自身免疫性疾病,其特征是循环血小板数量显著减少及常伴有出血。虽然ITP的发病机制尚未完全阐明,但目前普遍认为 T、B淋巴细胞功能紊乱参与了ITP的发病机制。ITP临床表现复杂,治疗过程存在异质性,其原因在于病理机制的复杂性。因此,更好地了解ITP的不同发病机制对于探索更有效的治疗是必要的。最近,越来越多的研究揭示免疫抑制性细胞对ITP的发病机制存在重要影响。为此,本文主要综述不同免疫抑制细胞在ITP中的作用,以期为临床探索该病的治疗方法提供帮助。
Abstract:
Immune thrombocytopenia (ITP) is an autoimmune disease characterized by a significant reduction in the number of circulating platelets and often accompanied by bleeding.Although the pathogenesis of ITP has not been fully elucidated, it is generally believed that the dysfunction of T and B lymphocytes is involved in the pathogenesis of ITP.The clinical manifestations of ITP are complex and the treatment process is heterogeneous. The reason lies in the complexity of the pathological mechanism.Therefore, a better understanding of the different pathogenesis of ITP is necessary to explore more effective treatments.Recently, more and more studies have revealed that immunosuppressive cells have an important influence on the pathogenesis of ITP.To this end, this article mainly reviews the role of different immunosuppressive cells in ITP, in order to provide help for clinical exploration of the treatment of the disease.

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更新日期/Last Update: 1900-01-01