[1]疏 腾,胡胜红,叶 慧,等.静脉输注右美托咪定对甲状腺切除手术患者术后恢复质量的影响[J].医学信息,2022,35(09):161-164.[doi:10.3969/j.issn.1006-1959.2022.09.041]
　SHU Teng,HU Sheng-hong,YE Hui,et al.Effect of Intravenous Infusion of Dexmedetomidine on Postoperative Recovery Quality in Patients Undergoing Thyroid Surgery[J].Medical Information,2022,35(09):161-164.[doi:10.3969/j.issn.1006-1959.2022.09.041]
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静脉输注右美托咪定对甲状腺切除手术患者术后恢复质量的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年09期
页码:
161-164
栏目:
药物与临床
出版日期:
2022-05-01

文章信息/Info

Title:
Effect of Intravenous Infusion of Dexmedetomidine on Postoperative Recovery Quality in Patients Undergoing Thyroid Surgery
文章编号:
1006-1959（2022）09-0161-04
作者:
疏 腾; 胡胜红; 叶 慧; 等
（安徽医科大学附属安庆医院麻醉科，安徽 安庆 246003）
Author(s):
SHU Teng; HU Sheng-hong; YE Hui; et al.
(Department of Anesthesia,Anqing Hospital Affiliated with Anhui Medical University,Anqing 246003,Anhui,China)
关键词:
右美托咪定; QoR-15量表; 术后恢复质量; 甲状腺手术
Keywords:
Dexmedetomidine; QoR-15 Scale; Quality of postoperative recovery; Thyroid surgery
分类号:
R581
DOI:
10.3969/j.issn.1006-1959.2022.09.041
文献标志码:
A
摘要:
目的 评价静脉输注右美托咪定对甲状腺手术患者术后恢复质量的影响。方法 选取2020年8月-2021年4月我院择期行甲状腺手术患者80例，按照随机数字表法分为右美托咪定组（D组）和对照组（C组），每组40例。D组于麻醉诱导前静脉输注右美托咪定负荷量1 μg/kg，时间为10 min，继以0.4 μg/（kg·h）的速度持续输注至手术结束前30 min；C组则输注等容量生理盐水。比较两组手术时间、麻醉时间、瑞芬太尼用量、QoR-15评分、VAS评分、术后镇痛补救和恶心呕吐发生情况。结果 两组手术时间和麻醉时间比较，差异无统计学意义（P＞0.05）；D组瑞芬太尼用量少于C组，差异有统计学意义（P＜0.05）；D组术后第1天身体舒适度、情绪状态、疼痛和QoR-15总评分均高于C组，差异有统计学意义（P＜0.05），两组心理支持和身体独立性评分比较，差异无统计学意义（P＞0.05）；D组术后2、4、8、12 h VAS评分低于C组，差异有统计学意义（P＜0.05）；两组术后24 h VAS评分比较，差异无统计学意义（P＞0.05）；D组术后第1次需要镇痛补救的时间长于C组，需要镇痛补救的人数、术后曲马多总用量以及恶心呕吐发生率低于C组，差异有统计学意义（P＜0.05）。结论 静脉输注右美托咪定可以改善甲状腺手术患者的术后恢复质量，提供良好的术后镇痛，降低术后恶心呕吐发生率。
Abstract:
Objective To evaluate the effect of intravenous dexmedetomidine on postoperative recovery quality in patients undergoing thyroid surgery.Methods Eighty patients undergoing thyroid surgery in our hospital from August 2020 to April 2021 were randomly divided into dexmedetomidine group (group D) and control group (group C), with 40 cases in each group. Group D received intravenous infusion of dexmedetomidine load of 1 μg/kg before anesthesia induction for 10 min, followed by continuous infusion at the rate of 0.4 μg/(kg·h) until 30 min before operation. Group C was infused with saline. The operation time, anesthesia time, remifentanil dosage, QoR-15 score, VAS score, postoperative analgesia and nausea and vomiting were compared between the two groups.Results There was no significant difference in operation time and anesthesia time between the two groups (P>0.05); the dosage of remifentanil in group D was less than that in group C, and the difference was statistically significant (P<0.05). The total scores of physical comfort, emotional state, pain and QoR-15 in group D on the first day after operation were higher than those in group C, and the difference was statistically significant (P<0.05); there was no significant difference in psychological support and physical independence scores between the two groups (P>0.05). The VAS score of group D was lower than that of group C at 2, 4, 8, 12 h after operation, and the difference was statistically significant (P<0.05); there was no significant difference in VAS score at 24 h after operation between the two groups (P>0.05). The first time after operation in group D was longer than that in group C, the number of patients requiring analgesia, the total amount of tramadol after operation and the incidence of nausea and vomiting were lower than those in group C, the difference was statistically significant (P<0.05).Conclusion Intravenous infusion of dexmedetomidine can improve the postoperative recovery quality of patients undergoing thyroid surgery, provide good postoperative analgesia, and reduce the incidence of postoperative nausea and vomiting.

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更新日期/Last Update: 1900-01-01