[1]周 林.瑞芬太尼联合丙泊酚在无痛胃肠镜麻醉中的应用效果[J].医学信息,2022,35(20):133-135.[doi:10.3969/j.issn.1006-1959.2022.20.036]
　ZHOU Lin.Application Effect of Remifentanil Combined with Propofol in Painless Gastroenteroscopy Anesthesia[J].Journal of Medical Information,2022,35(20):133-135.[doi:10.3969/j.issn.1006-1959.2022.20.036]
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瑞芬太尼联合丙泊酚在无痛胃肠镜麻醉中的应用效果()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年20期
页码:
133-135
栏目:
药物与临床
出版日期:
2022-10-15

文章信息/Info

Title:
Application Effect of Remifentanil Combined with Propofol in Painless Gastroenteroscopy Anesthesia
文章编号:
1006-1959（2022）20-0133-03
作者:
周 林
（永修县人民医院麻醉科，江西 永修 330304）
Author(s):
ZHOU Lin
(Department of Anesthesiology,Yongxiu County People’s Hospital,Yongxiu 330304,Jiangxi,China)
关键词:
盐酸瑞芬太尼; 丙泊酚; 无痛胃肠镜; 麻醉效果
Keywords:
Remifentanil hydrochloride; Propofol; Painless gastrointestinal endoscopy; Anesthetic effect
分类号:
R614
DOI:
10.3969/j.issn.1006-1959.2022.20.036
文献标志码:
A
摘要:
目的 研究瑞芬太尼联合丙泊酚在无痛胃肠镜麻醉中的应用效果。方法 选取2020年3月-2021年3月在我院进行无痛胃肠镜检查的86例患者为研究对象，采用随机数字表法分为对照组和观察组，各43例。对照组单纯采用丙泊酚麻醉，观察组在对照组基础上联合盐酸瑞芬太尼麻醉；比较两组不同时间段平均动脉压（MAP）、心率（HR）、血氧饱和度（SpO2）、麻醉诱导时间、苏醒时间、丙泊酚用量、Ramsay镇静评分、疼痛评分及不良反应发生情况。结果 检查开始1 min、检查后3 min，两组MAP、HR均低于吸氧前，观察组高于对照组（P＜0.05）；两组SpO2在检查开始1 min、检查后3 min与吸氧前比较，差异无统计学意义（P＞0.05）；观察组麻醉诱导时间、苏醒时间、丙泊酚用量均小于对照组（P＜0.05）；观察组Ramsay镇静、疼痛评分均小于对照组（P＜0.05）；观察组不良反应发生率为6.98%，小于对照组的16.28%（P＜0.05）。结论 瑞芬太尼联合丙泊酚在无痛胃肠镜检查中具有良好的麻醉效果，可减小对心率、动脉压等的影响，缩短苏醒、麻醉诱导时间，减少丙泊酚用量，降低镇静评分及不良反应，具有理想的应用有效性和安全性。
Abstract:
Objective To study the application effect of remifentanil combined with propofol in painless gastrointestinal endoscopy anesthesia.Methods A total of 86 patients who underwent painless gastrointestinal endoscopy in our hospital from March 2020 to March 2021 were selected as the research objects. They were divided into control group and observation group by random number table method, with 43 cases in each group. The control group was only anesthetized with propofol, and the observation group was combined with remifentanil hydrochloride anesthesia on the basis of the control group. The mean arterial pressure (MAP), heart rate (HR), blood oxygen saturation (SpO2), anesthesia induction time, recovery time, propofol dosage, Ramsay sedation score, pain score and adverse reactions were compared between the two groups.Results At 1 min after examination and 3 min after examination, MAP and HR in the two groups were lower than those before oxygen inhalation, and those in the observation group were higher than the control group (P<0.05). There was no significant difference in SpO2 between the two groups at 1 min after examination, 3 min after examination and before oxygen inhalation (P>0.05). The anesthesia induction time, recovery time and propofol dosage in the observation group were less than those in the control group (P<0.05). The Ramsay sedation and pain scores in the observation group were lower than those in the control group (P<0.05). The incidence of adverse reactions in the observation group was 6.98%, which was lower than 16.28% in the control group (P<0.05).Conclusion Remifentanil combined with propofol has a good anesthetic effect in painless gastrointestinal endoscopy, which can reduce the influence on heart rate and arterial pressure, shorten the time of awakening and anesthesia induction, reduce the dosage of propofol, reduce the sedation score and adverse reactions, and has ideal application effectiveness and safety.

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更新日期/Last Update: 1900-01-01