[1]游庆港,苏比努尔·依力哈尔,古丽妮尕尔·艾合买提,等.Zwolle风险评分联合BNP对急性ST段抬高型心肌梗死行PCI术后院内主要不良心血管事件的预测价值[J].医学信息,2023,36(08):108-111.[doi:10.3969/j.issn.1006-1959.2023.08.022]
　YOU Qing-gang,Subinur·Elhar,Gvlnigar·Ahmat,et al.The Predictive Value of Zwolle Risk Score Combined with BNP for In-hospital Major Adverse Cardiovascular Events After PCI in Patients with Acute ST-segment Elevation Myocardial Infarction[J].Journal of Medical Information,2023,36(08):108-111.[doi:10.3969/j.issn.1006-1959.2023.08.022]
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Zwolle风险评分联合BNP对急性ST段抬高型心肌梗死行PCI术后院内主要不良心血管事件的预测价值()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年08期
页码:
108-111
栏目:
论著
出版日期:
2023-04-15

文章信息/Info

Title:
The Predictive Value of Zwolle Risk Score Combined with BNP for In-hospital Major Adverse Cardiovascular Events After PCI in Patients with Acute ST-segment Elevation Myocardial Infarction
文章编号:
1006-1959（2023）08-0108-04
作者:
游庆港; 苏比努尔·依力哈尔; 古丽妮尕尔·艾合买提; 等
（新疆医科大学第二附属医院心血管内科，新疆 乌鲁木齐 830000）
Author(s):
YOU Qing-gang; Subinur·Elhar; Gvlnigar·Ahmat; et al.
(Department of Cardiovascular Medicine,the Second Affiliated Hospital of Xinjiang Medical University,Urumqi 830000,Xinjiang,China)
关键词:
主要不良心血管事件; 急性ST段抬高型心肌梗死; 脑利钠肽; Zwolle风险评分
Keywords:
Major adverse cardiovascular events; Acute ST segment elevation myocardial infarction; Brain natriuretic peptide; Zwolle risk score
分类号:
R542.2+2
DOI:
10.3969/j.issn.1006-1959.2023.08.022
文献标志码:
A
摘要:
目的 探讨Zwolle风险评分（ZRS）联合脑利钠肽（BNP）预测对急性ST段抬高型心肌梗死（STEMI）患者行急诊经皮冠状动脉介入治疗（PCI）术后院内发生主要不良心血管事件（MACE）的预测价值。方法 选取2021年1月-2022年7月于新疆医科大学第二附属医院行急诊PCI的STEMI患者136例为研究对象，根据患者是否发生院内MACE分为非MACE组与MACE组，比较两组临床资料，并运用二分类Logistic回归分析STEMI患者行PCI术后MACE的独立危险因素，同时通过ROC曲线分析ZRS联合BNP、ZRS、BNP对STEMI患者PCI术后MACE的预测价值。结果 136例行急诊PCI的STEMI患者中有21例发生MACE，发生率为15.44%。两组年龄、ZRS评分、收缩压、舒张压、WBC、BNP比较，差异有统计学意义（P＜0.05）；而两组心率、高血压、性别、TG、TC、HDL-C、LDL-C比较，差异无统计学意义（P＞0.05）；ROC曲线分析显示，ZRS、BNP联合预测STEMI患者MACE发生风险的AUC高于ZRS和BNP，其敏感度为81.00%，特异度为92.20%；多因素二分类Logistic回归分析显示，WBC、ZRS+BNP为STEMI患者行PCI术后MACE的独立危险因素。结论 与单一的BNP、ZRS相比，ZRS+BNP在一定程度上更适合预测STEMI患者行PCI术后MACE。
Abstract:
Objective To investigate the predictive value of Zwolle risk score (ZRS) combined with brain natriuretic peptide (BNP) for major adverse cardiovascular events (MACE) in patients with acute ST-segment elevation myocardial infarction (STEMI) after emergency percutaneous coronary intervention (PCI).Methods A total of 136 STEMI patients who underwent emergency PCI in the Second Affiliated Hospital of Xinjiang Medical University from January 2021 to July 2022 were selected as the research objects. According to whether the patients had in-hospital MACE, they were divided into non-MACE group and MACE group. The clinical data of the two groups were compared, and the independent risk factors of MACE after PCI in STEMI patients were analyzed by binary Logistic regression. At the same time, the predictive value of ZRS combined with BNP, ZRS and BNP for MACE after PCI in STEMI patients was analyzed by ROC curve.Results MACE occurred in 21 of 136 STEMI patients undergoing emergency PCI, with an incidence of 15.44%. There were significant differences in age, ZRS score, systolic blood pressure, diastolic blood pressure, WBC and BNP between the two groups (P<0.05), while there was no significant difference in heart rate, hypertension, gender, TG, TC, HDL-C and LDL-C between the two groups (P>0.05). ROC curve analysis showed that the AUC of ZRS combined with BNP in predicting the risk of MACE in STEMI patients was higher than that of ZRS and BNP, with a sensitivity of 81.00% and a specificity of 92.20%. Multivariate binary logistic regression analysis showed that WBC and ZRS + BNP were independent risk factors for MACE after PCI in STEMI patients.Conclusion Compared with single BNP and ZRS, ZRS + BNP is more suitable to predict MACE after PCI in STEMI patients to some extent.

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更新日期/Last Update: 1900-01-01