[1]李晓丽,董 益,王 莹.对比敏感度作为原发性闭角型青光眼术后随访评估指标的初步研究[J].医学信息,2023,36(12):129-132.[doi:10.3969/j.issn.1006-1959.2023.12.025]
　LI Xiao-li,DONG Yi,WANG Ying.A Preliminary Study of Contrast Sensitivity as a Postoperative Follow-up Evaluation Index for Primary Angle-closure Glaucoma[J].Journal of Medical Information,2023,36(12):129-132.[doi:10.3969/j.issn.1006-1959.2023.12.025]
点击复制

对比敏感度作为原发性闭角型青光眼术后随访评估指标的初步研究()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年12期
页码:
129-132
栏目:
论著
出版日期:
2023-06-15

文章信息/Info

Title:
A Preliminary Study of Contrast Sensitivity as a Postoperative Follow-up Evaluation Index for Primary Angle-closure Glaucoma
文章编号:
1006-1959（2023）12-0129-04
作者:
李晓丽; 董 益; 王 莹
（天津市眼科医院/天津市眼科学与视觉科学重点实验室/天津市眼科研究所/天津医科大学眼科临床学院，天津 300020）
Author(s):
LI Xiao-li; DONG Yi; WANG Ying
(Tianjin Eye Hospital/Tianjin Key Laboratory of Ophthalmology and Visual Science/Tianjin Institute of Ophthalmology/Clinical School of Ophthalmology,Tianjin Medical University,Tianjin 300020,China)
关键词:
青光眼; 对比敏感度; 空间频率; LogMAR视力; 视野; 视力
Keywords:
Glaucoma; Contrast sensitivity; Spatial frequency; LogMAR vision; View; Vision
分类号:
R775.2
DOI:
10.3969/j.issn.1006-1959.2023.12.025
文献标志码:
A
摘要:
目的 对比三种评价原发性闭角型青光眼术后视功能变化情况的检测方法，探索应用对比敏感度作为原发性闭角型青光眼术后随访评估指标的可行性。方法 选取2020年10月-2021年10月在天津市眼科医院行手术治疗的66例（132只眼）作为青光眼组，青光眼组细分为两亚组：双眼中的一眼接受小梁切除术（66只眼）者设为TB组；另一眼接受激光虹膜周切术（66只眼）者设为LPI组。选取健康对照33例（66只眼）设为对照组。所有受试者均测量视力、视野和对比敏感度。结果 三组视力、视野以及空间频率（3 cpd、6 cpd、12 cpd、18 cpd）对比敏感度比较，差异有统计学意义（P＜0.05）；TB组、LPI组、对照组的视力、视野、空间频率（3 cpd、6 cpd、12 cpd、18 cpd）对比敏感度分别比较，差异有统计学意义（P＜0.05）；LPI组和对照组视野、空间频率（12 cpd、18 cpd）对比敏感度比较，差异有统计学意义（P＜0.05）；而视力以及空间频率（3 cpd、6 cpd）对比敏感度比较，差异无统计学意义（P＞0.05）；青光眼组4个空间频率下对比敏感度和视野的相关性（r=0.524、0.662、0.566、0.483，P＜0.05）均高于视力和视野之间的相关性（r=-0.337，P＜0.05），其中在3个空间频率（3 cpd、6 cpd、12 cpd）下差异有统计学意义（P＜0.05）。结论 对比敏感度检查可以作为原发性闭角型青光眼术后随访的病情评估指标。
Abstract:
Objective To compare three methods for evaluating the changes of visual function after primary angle-closure glaucoma surgery, and to explore the feasibility of using contrast sensitivity as a follow-up evaluation index for primary angle-closure glaucoma.Methods A total of 66 patients (132 eyes) who underwent surgical treatment in Tianjin Eye Hospital from October 2020 to October 2021 were selected as the glaucoma group. The glaucoma group was subdivided into two subgroups: 66 eyes underwent trabeculectomy in one of the two eyes were set as TB group; the other eye receiving laser peripheral iridectomy (66 eyes) was set as the LPI group. Thirty-three healthy controls (66 eyes) were selected as the control group. Visual acuity, visual field and contrast sensitivity were measured in all subjects.Results There were significant differences in visual acuity, visual field and spatial frequency (3 cpd, 6 cpd, 12 cpd, 18 cpd) contrast sensitivity among the three groups (P<0.05). There were significant differences in visual acuity, visual field and spatial frequency (3 cpd, 6 cpd, 12 cpd, 18 cpd) contrast sensitivity among TB group, LPI group and control group (P<0.05). There were significant differences in visual field and spatial frequency (12 cpd, 18 cpd) contrast sensitivity between LPI group and control group (P<0.05), but there was no significant difference in visual acuity and spatial frequency (3 cpd, 6 cpd) contrast sensitivity (P>0.05). The correlation between contrast sensitivity and visual field at four spatial frequencies (r=0.524, 0.662, 0.566, 0.483, P<0.05) was higher than that between visual acuity and visual field (r=-0.337, P<0.05) in the glaucoma group, and the difference was statistically significant at three spatial frequencies (3 cpd, 6 cpd, 12 cpd) (P<0.05).Conclusion Contrast sensitivity examination can be used as an evaluation index for postoperative follow-up of primary angle-closure glaucoma.

参考文献/References:

[1]Sun X,Dai Y,Chen Y,et al.Primary angle closure glaucoma: What we know and what we don’t know[J].Prog Retin Eye Res,2017,57:26-45.[2]Kang JM,Tanna AP.Glaucoma[J].Med Clin North Am,2021,105(3):493-510.[3]Amanullah S,Okudolo J,Rahmatnejad K,et al.The relationship between contrast sensitivity and retinal nerve fiber layer thickness in patients with glaucoma[J].Graefes Arch Clin Exp Ophthalmol,2017,255(12):2415-2422.[4]Fatehi N,Nowroozizadeh S,Henry S,et al.Association of Structural and Functional Measures With Contrast Sensitivity in Glaucoma[J].Am J Ophthalmol,2017,178:129-139.[5]Hirji SH,Hood DC,Liebmann JM,et al.Association of Patterns of Glaucomatous Macular Damage With Contrast Sensitivity and Facial Recognition in Patients With Glaucoma[J].JAMA Ophthalmol,2021,139(1):27-32.[6]董益.青光眼视功能评估和重建的相关研究[D].天津:天津医科大学,2015.[7]Schuster AK,Erb C,Hoffmann EM,et al.The Diagnosis and Treatment of Glaucoma[J].Dtsch Arztebl Int,2020,117(13):225-234.[8]Rao A,Pal A,Mohapatra S.Spaeth/Richman Contrast Sensitivity in Staging Glaucoma[J].Transl Vis Sci Technol,2020,9(13):39.[9]Stein JD,Khawaja AP,Weizer JS,et al.Glaucoma in Adults-Screening, Diagnosis, and Management: A Review[J].JAMA,2021,325(2):164-174.[10]Njeru SM,Osman M,Brown AM.The Effect of Test Distance on Visual Contrast Sensitivity Measured Using the Pelli-Robson Chart[J].Transl Vis Sci Technol,2021,10(2):32.[11]Rijal S,Cheng H,Marsack JD.Comparing the CamBlobs2 contrast sensitivity test to the near Pelli-Robson contrast sensitivity test in normally-sighted young adults[J].Ophthalmic Physiol Opt,2021,41(5):1125-1133.[12]Thakur S,Ichhpujani P,Kumar S,et al.Assessment of contrast sensitivity by Spaeth Richman Contrast Sensitivity Test and Pelli Robson Chart Test in patients with varying severity of glaucoma[J].Eye (Lond),2018,32(8):1392-1400.[13]延新年,范强,蒲晓莉.区域折射多焦点人工晶状体植入术后对比敏感度的比较研究[J].局解手术学杂志,2018,27(10):753-756.[14]Bham HA,Dewsbery SD,Denniss J.Unaltered Perception of Suprathreshold Contrast in Early Glaucoma Despite Sensitivity Loss[J].Invest Ophthalmol Vis Sci,2020,61(8):23.[15]Kuerten D,Fuest M,Walter P,et al.Association of ocular blood flow and contrast sensitivity in normal tension glaucoma[J].Graefes Arch Clin Exp Ophthalmol,2021,259(8):2251-2257.[16]周小强. 基于B/S的空间对比敏感度测量研究[D].合肥:安徽医科大学,2016.[17]Jammal AA,Ferreira BG,Zangalli CS,et al.Evaluation of contrast sensitivity in patients with advanced glaucoma: comparison of two tests[J].Br J Ophthalmol,2020,104(10):1418-1422.[18]Xu P,Lesmes LA,Yu D,et al.Mapping the Contrast Sensitivity of the Visual Field With Bayesian Adaptive qVFM[J].Front Neurosci,2020,14:665.[19]Ramezani K,Marín-Franch I,Hu R,et al.Prediction Accuracy of the Dynamic Structure-Function Model for Glaucoma Progression Using Contrast Sensitivity Perimetry and Confocal Scanning Laser Ophthalmoscopy[J].J Glaucoma,2018,27(9):785-793.[20]Choi AYJ,Nivison-Smith L,Phu J,et al.Contrast sensitivity isocontours of the central visual field[J].Sci Rep,2019,9(1):11603.

相似文献/References:

[1]吕沅彬,李静敏.青光眼激光治疗现状研究[J].医学信息,2018,31(07):34.[doi:10.3969/j.issn.1006-1959.2018.07.013]
　LV Yuan-bin,LI Jing-min.Study on Current Situation of Laser Therapy for Glaucoma[J].Journal of Medical Information,2018,31(12):34.[doi:10.3969/j.issn.1006-1959.2018.07.013]
[2]陈 行,汤永强.缓释制剂在眼科疾病治疗中的应用研究[J].医学信息,2021,34(02):65.[doi:10.3969/j.issn.1006-1959.2021.02.018]
　CHEN Hang,TANG Yong-qiang.Study on the Application of Sustained-release Preparations in the Treatment of Ophthalmic Diseases[J].Journal of Medical Information,2021,34(12):65.[doi:10.3969/j.issn.1006-1959.2021.02.018]
[3]李丹丹,刘 伟,张万红,等.局部降眼压药物对青光眼患者后视盘及其周围血流密度变化的影响[J].医学信息,2021,34(04):126.[doi:10.3969/j.issn.1006-1959.2021.04.033]
　LI Dan-dan,LIU Wei,ZHANG Wan-hong,et al.Effects of Local Intraocular Pressure-lowering Drugs on the Changes of Posterior Optic Disc and Surrounding Blood Flow Density in Patients with Glaucoma[J].Journal of Medical Information,2021,34(12):126.[doi:10.3969/j.issn.1006-1959.2021.04.033]
[4]陈思源,刘姗姗,范晓军,等.原发性青光眼患者虹膜变化的研究[J].医学信息,2021,34(08):53.[doi:10.3969/j.issn.1006-1959.2021.08.014]
　CHEN Si-yuan,LIU Shan-shan,FAN Xiao-jun,et al.Study on Changes of Iris in Patients with Primary Glaucoma[J].Journal of Medical Information,2021,34(12):53.[doi:10.3969/j.issn.1006-1959.2021.08.014]
[5]郑嫣妮,冯 骅.三联手术治疗真性小眼球继发青光眼的疗效评价[J].医学信息,2021,34(24):83.[doi:10.3969/j.issn.1006-1959.2021.24.018]
　ZHENG Yan-ni,FENG Hua.Efficacy Evaluation of Triple Surgery in the Treatment of True Small Eyeball Secondary Glaucoma[J].Journal of Medical Information,2021,34(12):83.[doi:10.3969/j.issn.1006-1959.2021.24.018]

更新日期/Last Update: 1900-01-01